The Association Between Different Revascularization Methods and Left Ventricular Functions and Serum sST2 Levels in Patients with Acute Myocardial Infarction

Year 2020, Volume: 73 Issue: 2, 118 - 123, 31.08.2020

Özge Çakmak Karaaslan , Serkan Ünlü , Murat Oguz Özilhan , Salih Topal , Serkan Bulguroğlu , Atiye Çengel

Abstract

Objectives: We investigated the effects of different revascularization methods on soluble ST2 (sST2) levels and echocardiographic parameters of left
ventricular systole and diastolic in patients admitted with acute myocardial infarction (AMI).
Materials and Methods: A total of 30 patients were included in the study. The study population was divided into two groups. Patients who underwent
primary percutaneous intervention (PCI) or fibrinolytic therapy admitted with AMI were formed the study groups. sST2 and echocardiography
parameters were compared during 3-month follow-up of patients.
Results: There was no difference between sST2 levels in both groups. Left ventricular ejection fraction (LVEF) was higher in the PCI group.
Conclusion: Consequently, the sST2 level did not change in AMI patients regardless of the revascularization method. LVEF was significantly higher
in the PCI group compared to the fibrinolytic group.

Keywords

Acute Myocardial Infarction , Soluble ST2 , Revascularization

Project Number

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Functions and Serum sST2 Levels in Patients with Acute Myocardial Infarction

Abstract

Amaç: Akut miyokart enfarktüsü (AME) ile başvuran hastalarda, farklı revaskülarizasyon yöntemlerinin çözülebilir ST2 (sST2) düzeyleri ve sol
ventrikül sistol ile diyastol ekokardiyografik parametreleri üzerine olan etkilerini araştırdık.
Gereç ve Yöntem: Çalışmaya toplam 30 hasta dahil edildi. Çalışma popülasyonu iki gruba ayrıldı. AME ile başvuran primer perkütan girişim (PKG)
uygulanan veya fibrinolitik uygulanan hastalar çalışma gruplarını oluşturdu. sST2 ve ekokardiyografi parametreler hastaların 3 aylık izlemi boyunca
karşılaştırıldı.
Bulgular: Her iki grupta sST2 düzeyi arasında fark izlenmedi. Sol ventrikül ejeksiyon fraksiyonu (SVEF) PKG yapılan grupta daha yüksek saptandı.
Sonuç: sST2 düzeyi AME hastalarında revaskülarizasyon yönteminden bağımsız olarak değişiklik göstermedi. PKG grubunda fibrinolitik grubuna
kıyasla SVEF anlamlı olarak daha yüksek bulundu

Keywords

Akut Miyokart Enfarktüsü , Çözülebilir ST2 , Revaskülarizasyon

Ethical Statement

Etik Kurul Onayı: Gazi Üniversitesi Tıp Fakültesi Klinik Araştırmalar Etik Kurulu’ndan alındı (karar no: 529). Hasta Onayı: Bilgilendirilmiş gönüllü onam formu alınmıştır. Hakem Değerlendirmesi: Editörler kurulunun dışından olan kişiler tarafından değerlendirilmiştir.

Supporting Institution

-

Project Number

-

Thanks

-

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