Long Axis to Short Axis Ratio of Breast Masses Pre-Diagnosed as Fibroadenomas on Ultrasonography. Can it Be a Useful Tool in Predicting Malignancy?

Ahmet Sürek; Mustafa Gökhan Ünsal; Ahmet Cem Dural; Muhammet Ferhat Çelik; Halil Fırat Baytekin; Enis Öztürk; Selin Kapan; Halil Alış

doi:10.4274/atfm.galenos.2019.47966

Long Axis to Short Axis Ratio of Breast Masses Pre-Diagnosed as Fibroadenomas on Ultrasonography. Can it Be a Useful Tool in Predicting Malignancy?

Abstract

Objectives: The purpose of this study was to calculate the long-axis-to-short axis ratio of breast masses pre-diagnosed as fibroadenoma (FA) on ultrasonography and determine its role in predicting malignancy. Materials and Methods: Between January 2011 and March 2014, 1,154 patients who underwent tru-cut biopsy for the evaluation of solid breast masses encountered on imaging were evaluated. Of these, patients with breast masses that were diagnosed as FA based on ultrasonographic findings were included (n=707) into the study. The long axis ratio of lesions with only 1-2 lobulations or had well circumscribed borders, homogenous echogenicity was measured parallel to the skin. The patient’s clinical characteristics and demographic data, imaging and pathology findings were reviewed. Results: Pathology findings revealed malignancy in 13 (1.8%) patients. Two of these were <40 years and 11 of them were >40 years (p=0.003). The long axis-short axis ratio was 1.8 for the benign cases and 1.4 for the malignant cases. The cut off value of the two ratios was calculated to be 1.4 (p=0.001). Most of the lesions were on right side and upper outer quadrant (n=394, 55.7% and n=389, 55% respectively). The rate of malignancy was similar according to location. Conclusion: Breast masses diagnosed as FA based on imaging with a long axis to short axis ratio less than 1.4 may be at an increased risk for malignancy despite the presence of benign sonographic features. In patients older than 40 with notable risk factors, a detailed review of pathological findings is strongly encouraged.

Keywords

Ethical Statement

Ethics Committee Approval: Bakırkoy Dr. Sadi Konuk Training and Research Hospital Ethical Committee for Clinical Research (Nr: 2014/09/26). Informed Consent: A written consent was obtained from all patients. Peer-review: Externally peer-reviewed. Authorship Contributions Surgical and Medical Practices: A.S., M.G.Ü., E.Ö., H.F.B., Concept: A.S., M.F.Ç., A.C.D., H.A., Design: M.G.Ü., A.S., M.F.Ç.,S.K., Data Collection or Processing: A.S., H.F.B., E.Ö., Analysis or Interpretation: S.K., H.A., A.C.D., Literature Search: A.C.D., H.F.B., Writing: A.S., M.G.Ü. Conflict of Interest: No conflict of interest was declared by the authors. Financial Disclosure: The authors declared that this study received no financial support.

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Details

Primary Language

English

Subjects

General Surgery

Journal Section

Research Article

Authors

Ahmet Sürek
0000-0002-5192-2481
Türkiye

Mustafa Gökhan Ünsal
0000-0002-6691-7511
Türkiye

Ahmet Cem Dural ^*
0000-0003-3479-725X
Türkiye

Muhammet Ferhat Çelik This is me
0000-0002-3697-0418
Türkiye

Halil Fırat Baytekin This is me
0000-0002-7086-4758
Türkiye

Enis Öztürk
0000-0002-8478-4652
Türkiye

Selin Kapan
0000-0001-9339-4894
Türkiye

Halil Alış
0000-0002-8008-2776
Türkiye

Publication Date

June 13, 2019

Submission Date

October 8, 2018

Acceptance Date

January 22, 2019

Published in Issue

Year 2019 Volume: 72 Number: 1

DOI

https://doi.org/10.4274/atfm.galenos.2019.47966

IZ

https://izlik.org/JA24XK54TM

Cite

RIS / Bibtex

APA

Sürek, A., Ünsal, M. G., Dural, A. C., Çelik, M. F., Baytekin, H. F., Öztürk, E., Kapan, S., & Alış, H. (2019). Long Axis to Short Axis Ratio of Breast Masses Pre-Diagnosed as Fibroadenomas on Ultrasonography. Can it Be a Useful Tool in Predicting Malignancy? Ankara Üniversitesi Tıp Fakültesi Mecmuası, 72(1), 106-110. https://doi.org/10.4274/atfm.galenos.2019.47966

AMA

1.Sürek A, Ünsal MG, Dural AC, et al. Long Axis to Short Axis Ratio of Breast Masses Pre-Diagnosed as Fibroadenomas on Ultrasonography. Can it Be a Useful Tool in Predicting Malignancy? Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2019;72(1):106-110. doi:10.4274/atfm.galenos.2019.47966

Chicago

Sürek, Ahmet, Mustafa Gökhan Ünsal, Ahmet Cem Dural, et al. 2019. “Long Axis to Short Axis Ratio of Breast Masses Pre-Diagnosed As Fibroadenomas on Ultrasonography. Can It Be a Useful Tool in Predicting Malignancy?”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 72 (1): 106-10. https://doi.org/10.4274/atfm.galenos.2019.47966.

EndNote

Sürek A, Ünsal MG, Dural AC, Çelik MF, Baytekin HF, Öztürk E, Kapan S, Alış H (June 1, 2019) Long Axis to Short Axis Ratio of Breast Masses Pre-Diagnosed as Fibroadenomas on Ultrasonography. Can it Be a Useful Tool in Predicting Malignancy? Ankara Üniversitesi Tıp Fakültesi Mecmuası 72 1 106–110.

IEEE

[1]A. Sürek et al., “Long Axis to Short Axis Ratio of Breast Masses Pre-Diagnosed as Fibroadenomas on Ultrasonography. Can it Be a Useful Tool in Predicting Malignancy?”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 72, no. 1, pp. 106–110, June 2019, doi: 10.4274/atfm.galenos.2019.47966.

ISNAD

Sürek, Ahmet - Ünsal, Mustafa Gökhan - Dural, Ahmet Cem - Çelik, Muhammet Ferhat - Baytekin, Halil Fırat - Öztürk, Enis - Kapan, Selin - Alış, Halil. “Long Axis to Short Axis Ratio of Breast Masses Pre-Diagnosed As Fibroadenomas on Ultrasonography. Can It Be a Useful Tool in Predicting Malignancy?”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 72/1 (June 1, 2019): 106-110. https://doi.org/10.4274/atfm.galenos.2019.47966.

JAMA

1.Sürek A, Ünsal MG, Dural AC, Çelik MF, Baytekin HF, Öztürk E, Kapan S, Alış H. Long Axis to Short Axis Ratio of Breast Masses Pre-Diagnosed as Fibroadenomas on Ultrasonography. Can it Be a Useful Tool in Predicting Malignancy? Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2019;72:106–110.

MLA

Sürek, Ahmet, et al. “Long Axis to Short Axis Ratio of Breast Masses Pre-Diagnosed As Fibroadenomas on Ultrasonography. Can It Be a Useful Tool in Predicting Malignancy?”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 72, no. 1, June 2019, pp. 106-10, doi:10.4274/atfm.galenos.2019.47966.

Vancouver

1.Ahmet Sürek, Mustafa Gökhan Ünsal, Ahmet Cem Dural, Muhammet Ferhat Çelik, Halil Fırat Baytekin, Enis Öztürk, Selin Kapan, Halil Alış. Long Axis to Short Axis Ratio of Breast Masses Pre-Diagnosed as Fibroadenomas on Ultrasonography. Can it Be a Useful Tool in Predicting Malignancy? Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2019 Jun. 1;72(1):106-10. doi:10.4274/atfm.galenos.2019.47966