Assessment of Effectiveness and Safety of Upper Gastrointestinal System Endoscopy in Geriatric Patients
Year 2018,
Volume: 71 Issue: 3, 228 - 233, 31.12.2018
Evrim Kahramanoğlu Aksoy
,
Muhammet Yener Akpınar
,
Ferdane Pirinççi Sapmaz
Zeynep Göktaş
,
Metin Uzman
,
Yaşar Nazlıgül
Abstract
Objectives: Upper gastrointestinal system (GIS) endoscopy is an important diagnostic and therapeutic tool in geriatric patients, similarly to other
age groups. Here we aimed to present the indications, endoscopic and pathologic findings and also endoscopy related complications of upper
endoscopic procedures in our geriatric population.
Materials and Methods: This study was designed as a retrospective study. Patients over 65 years old who had either diagnostic and/or therapeutic
upper gastrointestinal system endoscopy between 1 January 2017-1 January 2018 in Keçiören Training and Research Hospital were enrolled into the
study. Based on their age, patients were divided into two subgroups: group 1: patients aged between 65-80 years old and group 2: patients aged
over 80 years old.
Results: Overall 1154 patients (median age 74.2±6.38, male/female: 44.7/55.3) were enrolled into the study. Tissue biopsy was performed in 1018
patients. The most frequent upper GIS endoscopy indication was dyspepsia (86.3%). Gastritis (81.5%) and lower esophageal sphincter (LES) relaxation
(34%) were the most frequent endoscopic findings. Nevertheless the frequency of gastric cancer and peptic ulcer were 1.4% and 1.1%, respectively.
The frequency of H. pylori in our patients was 41.7%. Between two groups, endoscopy indications, endoscopic findings and frequency of H. pylori
were not significantly different. We did not observe any complication and upper GIS endoscopy associated mortality in our patientsConclusion: Upper GIS endoscopy can be perform in terms of diagnostic or therapeutic with safely in geriatric patients even if patient is extremely
elder. Age, alone must not a router to decide upper GIS endoscopy in geriatric patient.
References
-
1. Franceschi M, Di Mario F, Leandro G, et al. Acid-related disorders in the elderly. Best Pract Res Clin Gastroenterol. 2009;23:839-848.
-
2. Jim MA, Pinheiro PS, Carreira H, et al. Stomach cancer survival in the United States by race and stage (2001-2009): Findings from the CONCORD-2 study.
Cancer. 2017;24:4994-5013.
-
3. Wongrakpanich S, Wongrakpanich A, Melhado K, et al. A Comprehensive Review of Non-Steroidal Anti-Inflammatory Drug Use in The Elderly. Aging Dis. 2018;9:143-150.
-
4. Kandemir A, Arabul M, Çelik M, ve ark. Yaşlı Hastalarda Gastrointestinal Endoskopik İncelemerin Değerlendirilmesi. Turkish Journal of Geriatrics 2013;16:43-47.
-
5. Durazzo M, Campion D, Fagoonee S, Pellicano R. Gastrointestinal tract disorders in the elderly. Minerva Med. 2017;108:575-591.
-
6. Clarke GA, Jacobson BC, Hammett RJ, et al. The indications, utilization and safety of gastrointestinal endoscopy in an extremely elderly patients cohort. Endoscopy. 2001;33:580-584
-
7. Seinelä L, Ahvenainen J, Rönneikkö J, et al. Reasons for and outcome of upper gastrointestinal endoscopy in patients aged 85 years or more: retrospective study. BMJ. 1998;317:575-580.
-
8. Lee TC, Huang SP, Yang JY, et al. Age is not a discriminating factor for outcomes of therapeutic upper gastrointestinal endoscopy. Hepatogastroenterology. 2007;54:1319-1322.
-
9. Kawaguchi K, Kurumi H, Takeda Y, et al. Management for non-variceal bleeding in elderly patients: the gastrointestinal bleeding in elderly patients: the experience of a tertiary university hospital. Ann Transl Med. 2017;5:181.
-
10. Van Kouwen MC, Drenth JP, Verhoeven HM, et al. Upper gastrointestinal endoscopy in patients aged 85 years or more. Results of a feasibility study in a district general hospitalArch Gerontol Geriatr. 2003;37:45-50.
-
11. Archimandritis A, Spiliadis C, Tzivras M, et al. Gastric epithelial polyps: a retrospective endoscopic study of 12974 symptomatic patients. Ital J Gastroenterol. 1996;28:387-390
-
12. Jalving M, Koornstra JJ, Wesseling J, et al. Increased risk of fundic gland polyps during long-term proton pump inhibitor therapy. Aliment Pharmacol Ther. Aliment Pharmacol Ther. 2006;24:1341-1348.
-
13. Pilotto A. Aging and the gastrointestinal tract. Ital J Gastroenterol Hepatol 1999;31:137-153.
-
14. Pilotto A, Franceschi M, Valerio G, et al. Helicobacter pylori infection in elderly patients with peptic ulcer. Age Ageing. 1999;28:412-414.
-
15. Nagini S. Carcinoma of the stomach: A review of epidemiology, pathogenesis, molecular genetics and chemoprevention. World J Gastrointest Oncol 2012;4:156-169.
-
16. Daniel VT, Wiseman JT, Flahive J,et al. Predictors of mortality in the elderly after open repair for perforated peptic ulcer disease J Surg Res. 2017l;215:108-113.
Geriatrik Hastalarda Üst Gastrointestinal Sistem Endoskopisinin Etkinlik ve Güvenilirliğinin Değerlendirilmesi
Year 2018,
Volume: 71 Issue: 3, 228 - 233, 31.12.2018
Evrim Kahramanoğlu Aksoy
,
Muhammet Yener Akpınar
,
Ferdane Pirinççi Sapmaz
Zeynep Göktaş
,
Metin Uzman
,
Yaşar Nazlıgül
Abstract
Amaç: Üst gastrointestinal sistem (GİS) endoskopisi diğer hastalarda olduğu gibi geriatrik hastalarda da önemli bir tanısal ve terapötik araçtır. Biz
bu çalışmada geriatrik hastalarımızda yapılan üst GİS endoskopi işlemlerinin endikasyonlarını, endoskopide tanı alan lezyonların sıklığını ve bu yaş
grubunun mide patolojilerinin değerlendirilmesini amaçladık.
Gereç ve Yöntem: Bu çalışmaya Sağlık Bilimleri Üniversitesi, Keçiören Eğitim ve Araştırma Hastanesi, Gastroenteroloj Bilim Dalı Endoskopi Ünitesi’nde
1 Ocak 2017-1 Ocak 2018 tarihleri arasında üst gastrointestinal sistem endoskopisi yapılan 65 yaş ve üzeri hastalar retrospektif olarak dahil edildi.
Çalışmaya alınan hastalar yaşlarına göre iki gruba ayrıldı: 65-80 yaş arası grup 1 ve 80 yaş üzeri grup 2.
Bulgular: Çalışmaya toplam 1154 hasta (yaş ortalaması: 74,2±6,38, erkek/kadın: 44,7/55,3) alındı. Bu hastaların 1018 tanesinden endoskopi
esnasında biyopsi ve/veya doku örneklemesi yapıldı. En sık endoskopi endikasyonu dispepsi (%86,3) idi. Gastrit (%81,5) ve alt özofagus sfinkter
(AÖS) gevşekliği (%34) en sık izlenen endoskopik bulgularken mide kanseri %1,4, peptik ülser %1,1 sıklıkta izlendi. Hastalarımızda H. pylori sıklığı
%41,7’ydi. Endoskopi endikasyonları, endoskopik bulgular ve H. pylori varlığı gruplar arasında anlamlı farklılık göstermedi. Hastalarımızın hiçbirinde
tanısal ve terapötik üst GİS endoskopisine bağlı olarak komplikasyon ve mortalite izlenmedi.
Sonuç: Geriatrik hastalarda üst GİS endoskopisi, hastalar çok ileri yaş olsalar dahi tanısal ve terapötik amaçla güvenli bir şekilde kullanılabilir. Yaş
tek başına endoskopi işlemine karar vermede yönlendirici olmamalıdır
Ethical Statement
Etik Kurul Onayı: Çalışma retrospektif olduğu için etik kurul
onayı alınmamıştır.
Hasta Onayı: Çalışma retrospektif olduğu için hasta onayı
alınmamıştır.
Hakem Değerlendirmesi: Editörler kurulu tarafından
değerlendirilmiştir.
Yazarlık Katkıları
Cerrahi ve Medikal Uygulama: M.Y.A., E.K.A., F.P.S., M.U., Y.N.,
Konsept: M.Y.A., E.K.A., Dizayn: E.K.A., M.Y.A., Veri Toplama veya
İşleme: M.U., Y.N., F.P.S., Analiz veya Yorumlama: Z.G. Literatür
Arama: M.Y.A., F.P.S., Yazan: M.Y.A.,
Çıkar Çatışması: Yazarlar tarafından çıkar çatışması
bildirilmemiştir.
Finansal Destek: Yazarlar tarafından finansal destek
almadıkları bildirilmiştir.
References
-
1. Franceschi M, Di Mario F, Leandro G, et al. Acid-related disorders in the elderly. Best Pract Res Clin Gastroenterol. 2009;23:839-848.
-
2. Jim MA, Pinheiro PS, Carreira H, et al. Stomach cancer survival in the United States by race and stage (2001-2009): Findings from the CONCORD-2 study.
Cancer. 2017;24:4994-5013.
-
3. Wongrakpanich S, Wongrakpanich A, Melhado K, et al. A Comprehensive Review of Non-Steroidal Anti-Inflammatory Drug Use in The Elderly. Aging Dis. 2018;9:143-150.
-
4. Kandemir A, Arabul M, Çelik M, ve ark. Yaşlı Hastalarda Gastrointestinal Endoskopik İncelemerin Değerlendirilmesi. Turkish Journal of Geriatrics 2013;16:43-47.
-
5. Durazzo M, Campion D, Fagoonee S, Pellicano R. Gastrointestinal tract disorders in the elderly. Minerva Med. 2017;108:575-591.
-
6. Clarke GA, Jacobson BC, Hammett RJ, et al. The indications, utilization and safety of gastrointestinal endoscopy in an extremely elderly patients cohort. Endoscopy. 2001;33:580-584
-
7. Seinelä L, Ahvenainen J, Rönneikkö J, et al. Reasons for and outcome of upper gastrointestinal endoscopy in patients aged 85 years or more: retrospective study. BMJ. 1998;317:575-580.
-
8. Lee TC, Huang SP, Yang JY, et al. Age is not a discriminating factor for outcomes of therapeutic upper gastrointestinal endoscopy. Hepatogastroenterology. 2007;54:1319-1322.
-
9. Kawaguchi K, Kurumi H, Takeda Y, et al. Management for non-variceal bleeding in elderly patients: the gastrointestinal bleeding in elderly patients: the experience of a tertiary university hospital. Ann Transl Med. 2017;5:181.
-
10. Van Kouwen MC, Drenth JP, Verhoeven HM, et al. Upper gastrointestinal endoscopy in patients aged 85 years or more. Results of a feasibility study in a district general hospitalArch Gerontol Geriatr. 2003;37:45-50.
-
11. Archimandritis A, Spiliadis C, Tzivras M, et al. Gastric epithelial polyps: a retrospective endoscopic study of 12974 symptomatic patients. Ital J Gastroenterol. 1996;28:387-390
-
12. Jalving M, Koornstra JJ, Wesseling J, et al. Increased risk of fundic gland polyps during long-term proton pump inhibitor therapy. Aliment Pharmacol Ther. Aliment Pharmacol Ther. 2006;24:1341-1348.
-
13. Pilotto A. Aging and the gastrointestinal tract. Ital J Gastroenterol Hepatol 1999;31:137-153.
-
14. Pilotto A, Franceschi M, Valerio G, et al. Helicobacter pylori infection in elderly patients with peptic ulcer. Age Ageing. 1999;28:412-414.
-
15. Nagini S. Carcinoma of the stomach: A review of epidemiology, pathogenesis, molecular genetics and chemoprevention. World J Gastrointest Oncol 2012;4:156-169.
-
16. Daniel VT, Wiseman JT, Flahive J,et al. Predictors of mortality in the elderly after open repair for perforated peptic ulcer disease J Surg Res. 2017l;215:108-113.