Case Report

Cavenous Involvement in a Paint with Multiple Myeloma

Volume: 71 Number: 3 December 31, 2018
Buket Tuğan Yıldız *, Deniz Tuncel , Nursel Yurttutan , Şerife Çöklü Çöklü
EN TR

Cavenous Involvement in a Paint with Multiple Myeloma

Abstract

Multipl myeloma is a systemic disease with neoplastic proliferation of plasma cells. Cavernous sinus involvement is rare in multipl myeloma. The role of imaging with MRI to exclusion of involvement is great because the cavernous sinus can be evaluated very well by magnetic resonance imaging (MRI). Our case, a seventy seven-year-old female patient, applied to our policlinic with visual disturbance in the left eye. In the neurological examination of the patient; left eye was inside in the primer position, bilateral external view limitation was present marked in the left eye and downward view limitation was present in the left eye. Patient’s brain MRI showed patchy and nodal signals in the frontoparietal lob borderzone area may be compatible with infarct and causing asymmetric enhancement of the left cavernous sinus and expanding soft tissue lesion was detected. The patient was evaluated as multiple myeloma-associated left cavernous sinus involvement and the patient was directed to oncologic treatment center to re-evaluate her oncologic therapy. Since cavernous sinus involvement is rare in multiple myeloma, we found this patient worthy to present.

Keywords

Multipl Myeloma, Cavernous Sinus Involvement, Ophthalmoplegia

References

  1. 1. Chen K-Y, Hsu S, Chen M-T, et al. Multipl myeloma with cavernous sinus involvement. Kaohsiung J Med Sci. 2013;29:517-518.
  2. 2. Nieuwenhuizen L, Biesma DH. Central nervous system myelomatosis: review of the literature. Eur J Haematol. 2007;80:1-9.
  3. 3. Hata N.Y, Katai N, Oshitari T. Ophthalmic manifestations of hematopoietic malignancies. Case Reports in Ophthalmological medicine 2016.
  4. 4. Na J.H, Park S. H, Shin S.Y. Multipl myeloma manifesting as a fluctuating sixth nerve palsy. Kaohsiung J Med Sci. 2009;23:232-233.
  5. 5. Vande B.I, Stadrik T, Meurs A, et al. Extramedullary plasmacytoma of the cavernous sinus. Leuk Lymhoma. 2002;43:1691-1693.
  6. 6. Morkalban C, Martin- Aresti J, Patier JL, et al. Unusual cases in multipl myeloma and a dramatic response in metastatic lung cancer: case 3. intracranial plasmacytoma with cranial nerve neuropathy in multipl myeloma. J Clin Oncol. 2005;23:233-234.
  7. 7. Gozzetti A, Cerase A, Tarantino A, et al. Multipl myeloma involving the cavernous sinus: a report of 3 cases and response to bortezomib 2007;5:376-378.
  8. 8. Peker S, Abacioglu U, Bayrakli F, et al. Gama knife radiosurgery for cavernous sinus plasmacytoma in patient with breast cancer history. Surg Neurol. 2005;63:174-176.
  9. 9. Shpilberg KA, Esses SJ, Fowkes ME, et al. Imaging of extraosseous intracranial and intraspinal multiple myeloma, including central nervous system involvement. Clin Imaging. 2015;39:213-219.
  10. 10. Okamoto Y, Minami M, Tohno E, et al. Multifocal peripheral nerve involvement associated with multipl myeloma. Skeletal Radiol. 2007;36:1191-1193.
APA
Tuğan Yıldız, B., Tuncel, D., Yurttutan, N., & Çöklü, Ş. Ç. (2018). Cavenous Involvement in a Paint with Multiple Myeloma. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 71(3), 268-270. https://doi.org/10.4274/atfm.22932
AMA
1.Tuğan Yıldız B, Tuncel D, Yurttutan N, Çöklü ŞÇ. Cavenous Involvement in a Paint with Multiple Myeloma. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2018;71(3):268-270. doi:10.4274/atfm.22932
Chicago
Tuğan Yıldız, Buket, Deniz Tuncel, Nursel Yurttutan, and Şerife Çöklü Çöklü. 2018. “Cavenous Involvement in a Paint With Multiple Myeloma”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 71 (3): 268-70. https://doi.org/10.4274/atfm.22932.
EndNote
Tuğan Yıldız B, Tuncel D, Yurttutan N, Çöklü ŞÇ (December 1, 2018) Cavenous Involvement in a Paint with Multiple Myeloma. Ankara Üniversitesi Tıp Fakültesi Mecmuası 71 3 268–270.
IEEE
[1]B. Tuğan Yıldız, D. Tuncel, N. Yurttutan, and Ş. Ç. Çöklü, “Cavenous Involvement in a Paint with Multiple Myeloma”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 71, no. 3, pp. 268–270, Dec. 2018, doi: 10.4274/atfm.22932.
ISNAD
Tuğan Yıldız, Buket - Tuncel, Deniz - Yurttutan, Nursel - Çöklü, Şerife Çöklü. “Cavenous Involvement in a Paint With Multiple Myeloma”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 71/3 (December 1, 2018): 268-270. https://doi.org/10.4274/atfm.22932.
JAMA
1.Tuğan Yıldız B, Tuncel D, Yurttutan N, Çöklü ŞÇ. Cavenous Involvement in a Paint with Multiple Myeloma. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2018;71:268–270.
MLA
Tuğan Yıldız, Buket, et al. “Cavenous Involvement in a Paint With Multiple Myeloma”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 71, no. 3, Dec. 2018, pp. 268-70, doi:10.4274/atfm.22932.
Vancouver
1.Buket Tuğan Yıldız, Deniz Tuncel, Nursel Yurttutan, Şerife Çöklü Çöklü. Cavenous Involvement in a Paint with Multiple Myeloma. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2018 Dec. 1;71(3):268-70. doi:10.4274/atfm.22932