Ovülasyon İndüksiyonunda Ek Ajanlar
Abstract
Despite all advancement in ovarian stimulation programmes and laboratory techniques, the success of assisted reproductive techniques remains limited. Today, theprimary stimulating agents adopted as standard are clomiphene citrate and gonadotrophins. In some patients treated with stimulation protocols using those two
agents, adequate follicular development cannot be maintained or adequate amount and/or quality of oocytes cannot be achieved. Hence, development of somealternative treatment strategies in assisted reproductive technologies has been needed. Nowadays, those treatment methods are used in anovulatory infertilepatients and poor responders. Some additional agents are used in those patients in order to increase the amount and quality of achieved oocytes while decreasing treatment costs. In this sense, the best known additional agents are metformin, aromatase inhibitors, dehydrepiandrosterone, androgens, growth hormone, corticosteroids, and antioxidants.
Keywords
Aromatase inhibitors, Metformin, Ovulation Induction, Assisted Reproductive Technologies
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