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Unilateral Vokal Kord Paralizisi: Etiyolojik Faktörlerin Demografik Verilerle Karşılaştırılması

Year 2016, Volume: 69 Issue: 1, 61 - 64, 03.06.2016

Abstract

Objective: Unilateral vocal cord paralysis (UVCP) is characterized with fixation of vocal cords at different
positions depending on the level where the nerves is affected. Along the long course of recurrent laryngeal
and vagal nerve any lesion may lead to vocal cord paralysis. The aim of this study is to analyse causes of
UVCP and demographic findings of the patents.

Methods: We reviewed 47 patients with UVCP who applied to our clinic between 2013-2015 etiologically
and analysed them according to age, gender and side of the lesion. We compare patients in two groups,
under 40 years old (15 patients) and over 40 years old (32 patients) according to their ethiology.

Results: There was no statistically significant difference between the numbers of male and female patients
(p=0,307). There was no statistically significant difference between right and left sided lesions (p=0,884).
Thyroidectomy was the most frequent cause of UVCP (55,3%). While thyroidectomy was the most common
cause over the age of 40 (68,7% p=0,017), this was followed by malignancies. We found nonsurgical causes
as the most common cause under the age of 40 (66,7% p=0,028). Among them idiopathic UVCP was at the
top of the nonsurgical causes. Thyroidectomy was the second common cause under the age of 40. There
was no difference between two genders according to etiology. Side dominance was observed only at patients
with idiopathic UVCP and it was to the left side at this group.

Conclusion: UVCP is one of the most common cause of glottic gap and identifying the etiology is crucial to
determine the prognosis and additional diseases. Especially, malignancy is one of the most common cause
of UVCP over the age of 40, and detailed physical examination and imaging techniques should be performed.

Ethical Statement

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Supporting Institution

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Project Number

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Thanks

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References

  • 1.Dankbaar JW, Pameijer FA. Vocal cord paralysis: anatomy, imaging and pathology. Insights Imaging. 2014; 5: 743-751.
  • 2. Spataro EA, Grindler DJ, Paniello RC. Etiology and time presentation of unilateral vocal fold paralyis. Otolaryngol Head Neck Surg. 2014; 151: 286-293.
  • 3.􀀃 Al-Khtoum N, Shwakfeh N, Al-Safadi E, et al. Acquired unilateral vocal fold paralysis: retrospective analysis of a single institutional experience. N Am J Med Sci. 2013; 5: 699-702.
  • 4.􀀃 Takano S, Nito T, Tamaruya N, Kimura M, et al. Single institutional analysis of trends over 45 years in etiology of vocal paralysis. Auris Nasus Larynx. 2012; 39: 597-600.
  • 5.􀀃 Rosenthal LH, Benninger MS, Deeb RH. Vocal fold immobility. a longitudinal analysis of etiology over 20 years. Laryngoscope. 2007; 117: 1864-1870.
  • 6.􀀃 Dupuch V, Saroul N, Aumeran C, et al. Bilateral vocal cord abductor paralysis associated with primary herpes simplex infection: a case report. Eur Ann Otorhinolaryngol Head Neck Dis. 2012; 129: 272- 274.
  • 7.􀀃 Bachor E, Bonkowsky V, Hacki T. Herpess virus type I reactivation as a cause of a unilateral temporary paralysis of the vagus nevre. Eur Arch Otorhinolaryngol. 1996; 253:297-300.
  • 8.􀀃 Johns MM, Hogikyan ND. Simultaneous vocal fold and tongue paresis secondary to Epstein-Barr virus infection. Arch Otolaryngol Head Neck Surg. 2000; 126: 1491-1494.
  • 9.􀀃 Wang CC, Lin CC, Wang CP, et al. Laryngeal tuberculosis: a review of 26 cases. Otolaryngol Head Neck Surg. 2007; 137: 582-588.
  • 10.Francis DO, Pearce EC, Ni S, et al. Epidemiology of vocal fold paralysis after total thyroidectomy for well- differentiated thyroid cancer in medicare population. Otolarngol Head Neck Surg. 2014; 150: 548-557.
  • 11.Jeannon JP, Orabi AA, Bruch GA, et al. Diagnosis of recurrent laryngeal nerve palsy after thyroidectomy: a systematic review. Int J Clin Pract. 2009; 63: 624- 629.
  • 12.Efremidou EI, Papageorgiou MS, Liratzopoulos N, et al. The efficacy and safety of total thyroidectomy in the management of benign thyroid disease: a review of 932 cases. Can J Surg. 2009; 52: 39-44.
  • 13.Barczynski M, Konturek A, Pragacz K, et al. Intraoperative nerve monitoring can reduce prevalence of recurrent laryngeal nerve injury in thyroid reoperations: results of a retrospective cohort study. World J Surg. 2014; 38: 599-606.
  • 14.Sadowski SM, Soardo P, Leuchter I, et al. Systematic use of recurrent laryngeal nerve monitoring changes the operative strategy in planned bilateral thyroidectomy. Thyroid. 2013; 23: 329-333.
  • 15.Chan WF, Lang BH, Lo CV. The role of intraoperative neuromonitoring of recurrent laryngeal nerve during thyroidectomy: a comparative study on 1000 nerves at risk. Surgery. 2006; 140: 866-872.
  • 16. Hermann M, Hellebart C, Freissmuth M. Neuromonitoring in thyroid surgery: prospective evaluation of intraoperative electropysiological responses for the prediction of recurrent laryngeal nerve injury. Ann Surg. 2004; 240: 9-17.
  • 17.Netto Ide P, Vartanian JG, Ferraz PR, et al. Vocal fold immobility after thyroidectomy with intraoperative recurrent laryngeal nerve monitoring. Sao Paulo Med J. 2007; 125: 186-190.
  • 18. Kikura M, Suzuki K, Itagaki T, et al. Age and comorbidity as risk factors for vocal cord paralysis associated with tracheal intubation. Br J Anaesth. 2007; 98: 524-530.
  • 19.􀀃 Albasri A, Sawaf Z, Hussainy AS, et al. Histopathological patterns of thyroid disease in Al-Madinah Region of Saudi Arabia. Asian Pac J Cancer Prev. 2014; 15: 5565-5570.
  • 20.􀀃 Ça􀃸layan K, Çelik A. Benign tiroid hastal 􀃸nda ameliyat yöntemleri ve komplikasyonlar nn incelenmesi: tiroidektomi ve komplikasyonlar. Ulusal Cerrahi Dergisi. 2010; 26: 141-145.
  • 21. Spiro SG, Porter JC. Lung cancer- where are we today? Current advances in staging and nonsurgical treatment. Am J Respir Crit Care Med. 2002; 166: 1166-1196.
  • 22.Catlaruzza MS, Maisonneuve P, Boyle P. Epidemiology of laryngeal cancer. Eur J Cancer B Oral Oncol. 1996; 32B: 293- 305.
  • 23. Torramade JR, Hernandez-Lizoain JL, Benito C, et al. Cancer of the esophagus (I): its epidemiological, clinical and diagnostic assessment according to histological type. Rev Esp Enferm Dig. 1992; 82: 383-387.
  • 24. Yamada M, Hirano M, Ohkubo H. Recurrent laryngeal nerve paralysis. A 10- year review of 564 patients. Auris Nasus Larynx. 1983; 10 Suppl: S1-15.
  • 25. Benninger MS, Gillen JB, Altman JS. Changing etiology of vocal fold immobility. Laryngoscope. 1998; 108: 1346-1350.
  • 26.Havas T, Lowinger D, Priestly J. Unilateral vocal fold paralysis: causes, options and outcomes. Aust N Z J Surg. 1999; 69: 509-513.
  • 27.Yumoto E, Minoda R, Hyodo M, et al. Causes of recurrent laryngeal nevre paralysis. Auris Nasus Larynx. 2002;29: 41-45.

Unilateral Vokal Kord Paralizisi: Etiyolojik Faktörlerin Demografik Verilerle Kar􀄹la􀄹trlmas

Year 2016, Volume: 69 Issue: 1, 61 - 64, 03.06.2016

Abstract

Amaç:Unilateral vokal kord paraizileri ( UVKP) vokal kordların
sinirin etkilenme düzeyine ba􀃾l olarak farkl pozisyonlarda fikse olmasyla karakterizedir. Rekürren laringeal sinir ve vagal sinirin uzun seyri boyunca
kar􀄹la􀄹t􀃾 herhangi bir lezyon vokal kord paralizisine neden olabilir.Bu çal􀄹mann amac UVKPnin nedenlerini
ve hastalarn demografik verilerini incelemektir.

Yöntemler: 2013-2015 yllar arasnda klini􀃾imize ba􀄹vuran 47 UVKP hastasn etiyolojik açdan incelendi ve
ya􀄹, cinsiyet ve lezyonun tarafna göre de􀃾erlendirildi. 40 ya􀄹 alt (15 hasta) ve 40 ya􀄹 üstü (32 hasta) hastalar
iki grup halinde etiyolojik nedene göre kar􀄹la􀄹trld.

Bulgular: Kadn ve erkek saylar arasnda istatistiksel olarak anlaml bir fark izlenmedi (p=0,307). Sa􀃾 ve sol
tarafl lezyonlar arasnda istatistiksel olarak anlaml bir fark izlenmedi (p=0,884). Tiroidektomi en sk UVKP
nedeniydi (%55,3). 40 ya􀄹 üstünde tiroidektomi en sk nedenken (%68,7 p=0,017), bunu maligiteler takip
etmekteydi.40 ya􀄹 altnda en sk cerrahi olmayan nedenler olarak bulundu (%66,7 p=0,028). Cerrahi olmayan
nedenlerin en ba􀄹nda ise idiopatik UVKP yer almaktayd. Tiroidektomi ise 40 ya􀄹 altnda ikinci sklkta görülen
nedendi. Cinsiyetler arasnda etiyolojide bir fark izlenmedi. Sadece idiopatik UVKP hastalarnda taraf
üstünlü􀃾ü mevcuttu ve bu grupta taraf üstünlü􀃾ü sol tarafayd.

Sonuç: UVKP klinikte glottik yetmezlik yapan en sk nedenlerden biri olup etyolojinin belirlenmesi prognoz
ve ek hastalklarn tespiti açsndan oldukça önemlidir. Özellikle 40 ya􀄹 üstü vakalarda maligniteler UVKP nin
sk nedenlerinden biri oldu􀃾undan ayrntl fizik muayene ve görüntüleme yöntemleri ile inceleme yaplmal
dr.

Ethical Statement

-

Supporting Institution

-

Project Number

-

Thanks

-

References

  • 1.Dankbaar JW, Pameijer FA. Vocal cord paralysis: anatomy, imaging and pathology. Insights Imaging. 2014; 5: 743-751.
  • 2. Spataro EA, Grindler DJ, Paniello RC. Etiology and time presentation of unilateral vocal fold paralyis. Otolaryngol Head Neck Surg. 2014; 151: 286-293.
  • 3.􀀃 Al-Khtoum N, Shwakfeh N, Al-Safadi E, et al. Acquired unilateral vocal fold paralysis: retrospective analysis of a single institutional experience. N Am J Med Sci. 2013; 5: 699-702.
  • 4.􀀃 Takano S, Nito T, Tamaruya N, Kimura M, et al. Single institutional analysis of trends over 45 years in etiology of vocal paralysis. Auris Nasus Larynx. 2012; 39: 597-600.
  • 5.􀀃 Rosenthal LH, Benninger MS, Deeb RH. Vocal fold immobility. a longitudinal analysis of etiology over 20 years. Laryngoscope. 2007; 117: 1864-1870.
  • 6.􀀃 Dupuch V, Saroul N, Aumeran C, et al. Bilateral vocal cord abductor paralysis associated with primary herpes simplex infection: a case report. Eur Ann Otorhinolaryngol Head Neck Dis. 2012; 129: 272- 274.
  • 7.􀀃 Bachor E, Bonkowsky V, Hacki T. Herpess virus type I reactivation as a cause of a unilateral temporary paralysis of the vagus nevre. Eur Arch Otorhinolaryngol. 1996; 253:297-300.
  • 8.􀀃 Johns MM, Hogikyan ND. Simultaneous vocal fold and tongue paresis secondary to Epstein-Barr virus infection. Arch Otolaryngol Head Neck Surg. 2000; 126: 1491-1494.
  • 9.􀀃 Wang CC, Lin CC, Wang CP, et al. Laryngeal tuberculosis: a review of 26 cases. Otolaryngol Head Neck Surg. 2007; 137: 582-588.
  • 10.Francis DO, Pearce EC, Ni S, et al. Epidemiology of vocal fold paralysis after total thyroidectomy for well- differentiated thyroid cancer in medicare population. Otolarngol Head Neck Surg. 2014; 150: 548-557.
  • 11.Jeannon JP, Orabi AA, Bruch GA, et al. Diagnosis of recurrent laryngeal nerve palsy after thyroidectomy: a systematic review. Int J Clin Pract. 2009; 63: 624- 629.
  • 12.Efremidou EI, Papageorgiou MS, Liratzopoulos N, et al. The efficacy and safety of total thyroidectomy in the management of benign thyroid disease: a review of 932 cases. Can J Surg. 2009; 52: 39-44.
  • 13.Barczynski M, Konturek A, Pragacz K, et al. Intraoperative nerve monitoring can reduce prevalence of recurrent laryngeal nerve injury in thyroid reoperations: results of a retrospective cohort study. World J Surg. 2014; 38: 599-606.
  • 14.Sadowski SM, Soardo P, Leuchter I, et al. Systematic use of recurrent laryngeal nerve monitoring changes the operative strategy in planned bilateral thyroidectomy. Thyroid. 2013; 23: 329-333.
  • 15.Chan WF, Lang BH, Lo CV. The role of intraoperative neuromonitoring of recurrent laryngeal nerve during thyroidectomy: a comparative study on 1000 nerves at risk. Surgery. 2006; 140: 866-872.
  • 16. Hermann M, Hellebart C, Freissmuth M. Neuromonitoring in thyroid surgery: prospective evaluation of intraoperative electropysiological responses for the prediction of recurrent laryngeal nerve injury. Ann Surg. 2004; 240: 9-17.
  • 17.Netto Ide P, Vartanian JG, Ferraz PR, et al. Vocal fold immobility after thyroidectomy with intraoperative recurrent laryngeal nerve monitoring. Sao Paulo Med J. 2007; 125: 186-190.
  • 18. Kikura M, Suzuki K, Itagaki T, et al. Age and comorbidity as risk factors for vocal cord paralysis associated with tracheal intubation. Br J Anaesth. 2007; 98: 524-530.
  • 19.􀀃 Albasri A, Sawaf Z, Hussainy AS, et al. Histopathological patterns of thyroid disease in Al-Madinah Region of Saudi Arabia. Asian Pac J Cancer Prev. 2014; 15: 5565-5570.
  • 20.􀀃 Ça􀃸layan K, Çelik A. Benign tiroid hastal 􀃸nda ameliyat yöntemleri ve komplikasyonlar nn incelenmesi: tiroidektomi ve komplikasyonlar. Ulusal Cerrahi Dergisi. 2010; 26: 141-145.
  • 21. Spiro SG, Porter JC. Lung cancer- where are we today? Current advances in staging and nonsurgical treatment. Am J Respir Crit Care Med. 2002; 166: 1166-1196.
  • 22.Catlaruzza MS, Maisonneuve P, Boyle P. Epidemiology of laryngeal cancer. Eur J Cancer B Oral Oncol. 1996; 32B: 293- 305.
  • 23. Torramade JR, Hernandez-Lizoain JL, Benito C, et al. Cancer of the esophagus (I): its epidemiological, clinical and diagnostic assessment according to histological type. Rev Esp Enferm Dig. 1992; 82: 383-387.
  • 24. Yamada M, Hirano M, Ohkubo H. Recurrent laryngeal nerve paralysis. A 10- year review of 564 patients. Auris Nasus Larynx. 1983; 10 Suppl: S1-15.
  • 25. Benninger MS, Gillen JB, Altman JS. Changing etiology of vocal fold immobility. Laryngoscope. 1998; 108: 1346-1350.
  • 26.Havas T, Lowinger D, Priestly J. Unilateral vocal fold paralysis: causes, options and outcomes. Aust N Z J Surg. 1999; 69: 509-513.
  • 27.Yumoto E, Minoda R, Hyodo M, et al. Causes of recurrent laryngeal nevre paralysis. Auris Nasus Larynx. 2002;29: 41-45.
There are 27 citations in total.

Details

Primary Language English
Subjects Otorhinolaryngology
Journal Section Research Article
Authors

Ceren Ersöz 0000-0003-3739-2098

Arzu Tüzüner 0000-0001-9735-3504

Şule Demirci 0000-0002-6682-8500

İlker Akyildiz 0000-0002-1759-4699

Necmi Arslan 0000-0002-0355-2893

Project Number -
Publication Date June 3, 2016
Published in Issue Year 2016 Volume: 69 Issue: 1

Cite

APA Ersöz, C., Tüzüner, A., Demirci, Ş., … Akyildiz, İ. (2016). Unilateral Vokal Kord Paralizisi: Etiyolojik Faktörlerin Demografik Verilerle Karşılaştırılması. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 69(1), 61-64.
AMA Ersöz C, Tüzüner A, Demirci Ş, Akyildiz İ, Arslan N. Unilateral Vokal Kord Paralizisi: Etiyolojik Faktörlerin Demografik Verilerle Karşılaştırılması. Ankara Üniversitesi Tıp Fakültesi Mecmuası. June 2016;69(1):61-64.
Chicago Ersöz, Ceren, Arzu Tüzüner, Şule Demirci, İlker Akyildiz, and Necmi Arslan. “Unilateral Vokal Kord Paralizisi: Etiyolojik Faktörlerin Demografik Verilerle Karşılaştırılması”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 69, no. 1 (June 2016): 61-64.
EndNote Ersöz C, Tüzüner A, Demirci Ş, Akyildiz İ, Arslan N (June 1, 2016) Unilateral Vokal Kord Paralizisi: Etiyolojik Faktörlerin Demografik Verilerle Karşılaştırılması. Ankara Üniversitesi Tıp Fakültesi Mecmuası 69 1 61–64.
IEEE C. Ersöz, A. Tüzüner, Ş. Demirci, İ. Akyildiz, and N. Arslan, “Unilateral Vokal Kord Paralizisi: Etiyolojik Faktörlerin Demografik Verilerle Karşılaştırılması”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 69, no. 1, pp. 61–64, 2016.
ISNAD Ersöz, Ceren et al. “Unilateral Vokal Kord Paralizisi: Etiyolojik Faktörlerin Demografik Verilerle Karşılaştırılması”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 69/1 (June2016), 61-64.
JAMA Ersöz C, Tüzüner A, Demirci Ş, Akyildiz İ, Arslan N. Unilateral Vokal Kord Paralizisi: Etiyolojik Faktörlerin Demografik Verilerle Karşılaştırılması. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2016;69:61–64.
MLA Ersöz, Ceren et al. “Unilateral Vokal Kord Paralizisi: Etiyolojik Faktörlerin Demografik Verilerle Karşılaştırılması”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 69, no. 1, 2016, pp. 61-64.
Vancouver Ersöz C, Tüzüner A, Demirci Ş, Akyildiz İ, Arslan N. Unilateral Vokal Kord Paralizisi: Etiyolojik Faktörlerin Demografik Verilerle Karşılaştırılması. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2016;69(1):61-4.