Vezikoüreteral Reflüde Antibiyotik Profilaksisi

Year 2015, Volume: 68 Issue: 3, 129 - 132, 31.12.2015

Onur Telli , Barış Esen Tarkan Soygür , Berk Burgu

Abstract

Vesicoureteral reflux (VUR) which is associated with bladder dysfunction and increased risk of
urinary tract infection (UTI), is a common and important urinary system abnormality seen in
children. Although VUR spontaneously resolves in most of the cases, it might lead to severe
complications including reflux nephropathy, hypertension, UTI and bladder dysfunction. The
continuous antibiotic prophylaxis (CAP) in the management of VUR is first choice of therapy.
However, controversy exists on CAP in the current studies and some questions have not been
properly answered yet. In this paper the recent trends of CAP in VUR is reviewed under current
guidelines.

Keywords

Vesicoureteral Reflux , Prophylaxis , Antibiotic

Project Number

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Vezikoüreteral Reflüde Antibiyotik Profilaksisi

Abstract

Primer vezikoüreteral reflü (VUR) mesane disfonksiyonu ve üriner sistem enfeksiyonu riskinde
artıșla yakından ilișkili olan çocukluk çağına ait sık ve önemli bir patolojidir. VUR tanısı alan
çocukların çoğunda kendiliğinden geçse de, bir kısmında reflü nefropatisi, hipertansiyon, idrar
yolu enfeksiyonu ve mesane disfonksiyonu gibi olumsuz sonuçlar doğurabilmektedir. Antibiyotik
profilaksisi VUR’lu hastalarda ilk tedavi seçeneği olarak kabul edilirken son çalıșmalara
bakıldığında kesin bir görüș birliği olmadığı izlenmektedir. Bu derlemede primer VUR’de antibiyotik
profilaksisine güncel yaklașımlar güncel kılavuzlar eșliğinde değerlendirilmiștir.

Keywords

Vezikour̈ eteral Reflu , ̈ Pprofilaksi , Antibiyotik

Ethical Statement

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Supporting Institution

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Project Number

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Thanks

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