Epileptik Sendromlarda Göz Kapama Sensitivitesi ve Prognozla İlișkisi
Abstract
Aim: Eye-closure sensitivity may be observed in some patients with epilepsy and correlated to the prognosis of the epilepsy syndromes.
Patients and methods: The cases of seven patients with epilepsy demonstrating eye-closure sensitivity were reviewed for the diagnosis of the epilepsy syndromes and for the association with prognosis.
Results: All patients with eye-closure sensitivity had idiopathic generalized epilepsy, as juvenile myoclonic epilepsy in five patients, juvenile absence epilepsy in one patient and eyelid myoclonia with absences in another one. Six patients were seizure-free with low doses of valproate, and one patient with clonazepam treatment.
Conclusion: Eye-closure sensitivity may be correlated with good prognosis in patients with idiopathic generalized epilepsy like juvenile myoclonic epilepsy, juvenile absence epilepsy and eyelid myoclonia with absences.
Keywords
Eye-closure sensitivity, juvenile myoclonic epilepsy, juvenile absence epilepsy, eyelid myoclonia with absences, prognosis
References
- 1. Duncan JS, Panayiotopoulos CP. The differentiation of ‘eye closure’ from ‘eye closed’. In: Duncan JS, Panayiotopoulos CP, editors. Eyelid Myoclonia with Absences. London: John Libbey Company;1996;77-87.
- 2. Baykan-Kurt B, Gökyiit A, Parman Y, Kinay D, Gürses C. Eye Closure Related Spike and Wave Discharges: Clinical and Syndromic Associations. Clin Electrencephalogr 1999;30:106-110.
- 3. Sevgi EB, Saygı S, Ciger A. Eye closure sensitivity and epileptic syndromes: A retrospective study of 26 adult cases. Seziure 2007;16:17-21.
- 4. Guaranha MS, Filho GM, Lin K, Guilhoto LM, Caboclo LO, Yacubian EM. Prognosis of juvenile myoclonic epilepsy is related to endophenotypes.n Seizure. 2011;20:42-48.
- 5. Tekin Güveli B, Baykan B, Dörtcan N, Bebek N, Gürses C, Gökyiit A. Eye closure sensitivity in juvenile myoclonic epilepsy and its effect on prognosis. Seizure. 2013;22:867-871.