Mesenteric Vein Thrombosis Due to Protein S Deficiency in a Girl

Abstract

Mesenteric venous thrombosis (MVT) is a very rare condition in children, and may cause bowel infarction and gangrene. It may be caused by congenital or acquired factors, including protein S deficiency; a very rare genetic disorder. Here we report a case of MVT in a girl with protein S deficiency. The patient developed splenic necrosis and massive small bowel infarction sparing the colon. Contrast enhanced computed tomography led to prompt diagnosis of small bowel and splenic necrosis. The patient was treated successfully by resection of the necrotic bowel and anticoagulant therapy.

Keywords

• Mesenteric Venous Thrombosis
• Protein S Deficiency
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Protein S Eksikliğine Bağlı Mezenter Ven Trombozu Gelişen Kız Hasta

Abstract

Mezenterik ven trombozu (MVT) çocuklarda seyrek görülen bir durum olup barsak nekrozuna neden olabilmektedir. Mezenterik ven trombozu konjenital ve edinsel faktörlerle ilişkili olup Protein S eksikliği de bunların arasında yer alır. Burada protein S eksikliği olan bir kız çocuğunda görülen MVT olgusu sunulmaktadır. Kontrastlı bilgisayarlı tomografi incelemesi ile hastada dalak nekrozu ve geniş alanlarda kolonun korunduğu barsak nekrozu gözlenmiştir. Barsak rezeksiyonu ve antikoagulan tedavi sonrasında hasta başarıyla tedavi edilmiştir

Keywords

• Mezenter Ven Trombozu
• Protein S Eksikliği

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