Endometrial Stromal Nödül

Abstract

Endometrial stromal nodül (ESN), endometrial stromal tümörlerin benign ucunu olușturur. Tipik olarak düzgün sınırlı, kapsül bulundurmayan 0.5 ile 22 (ortalama 7) cm boyutlarında olabilen benignstromal nodüllerdir. Endometrial yerleșimde polipoid olan nodüller myometrial veya subserozal yerleșim de gösterebilir. Myometriuma invazyon olusturmaması en belirleyici mikroskopik özelliklerindendir. Oldukça nadir görülen bu antite özellikle küretaj materyallerinde düșük gradeli endometrial stromal sarkom (ESS) ile ayırıcı tanısı mümkün olmamaktadır. 64 yașında, postmenapozal kanama ve pelvik ağrı șikayetleri ile bașvuran hastanın küretaj materyalinde izlenen morfolojik bulgular nedeniyle yüksek gradeli malign tümör olarak raporlanmıș, daha sonra gönderilen histerektomi materyalinin incelenmesinde myometriuma invazyon görülmemiș ve olgu endometrial stromal nodül olarak raporlanmıștır

Keywords

• Endometrial Stromal Tümörler
• Miyometrium

Endometrial Stromal Nödül

Abstract

Endometrial stromal nodule (ESN) represents the benign end of the spectrum within the category of endometrial stromal tumors. Typically well-cicumscribed but not encapsulated tumors ranging in size from 0.5 to 22 (mean 7) cm. If centered in endometrium, they are freguently polypoid; they may be intramyometrial or subserozal. On low- power examination, these tumors are well demarcated from the adjacent myometrium. The differentiation of ESN from low-grade endometrial stromal sarcoma is not possible in a curretage specimen. 64 years old patient 's curetage material who has postmenoposal bleeding and pain semptoms was examined and diagnosed as endometrial stromal sarcoma (ESS). But at histerectomy specimen we saw any invazion of myometrium and change the diagnose as ESN.

Keywords

• Endometrial Stromal Tumors
• Myometrium
• patoloji

References

1. 1. Marisa R. Nucci, Oliva E. Gynecologic Pathology. A volume in the seriesFoundations in Diagnostic Pathology. 1st ed. China: 2009; 293-302.
2. 2. F.Z.Fdili Alaoui, H. Chaara, H. Bouguern, M. A. Melhouf, H.Fatemi, A. Belmlih, and A. Amarti. Endometrial Stromal Nodule: Report of a Case. Case Reports in Medicine. 2011 jan. Article ID 260647, doi:10.1155/2011/260647. 5 pages.
3. 3. C. Zaloudek and M.R. Hendricson. (Eds): Mesenchymal tumors of the uterus. In Blaustein’s Pathology of the Female Genital Tract. 5th ed., Springer, New York, NY, USA, 2001; 561-615.
4. 4. S.Elagöz, F. Kıvanç, H. Aker. Endometrial Stromal Tumors- a report of 5 cases. Aegean Pathology Jounal, 2005; 2: 140-145.
5. 5. K. Ryuko, K. Takahashi, K. Miyazaki, A case of endometrial stromal nodül,Shimane Journal of Medical Science, 1996; 14: 27-28.
6. 6. M.R. Hendricson, F.A. Tavassoli, R.L. Kempson, et al. Mesenchymal tumors and related lesions. In World Health Organization Classification of Tumours. Tumors of the Breast and Female Genital Organs. Fattaneh A. Tavassoli, Peter Devilee (Eds). IARC Press: Lyon 2003; 233-244
7. 7. K. R. Kim, S. Y. Jun, I. A. Park, et al. Endometrial Stromal tumor with limited infiltration and probable extrauterine metastasis: report of a case. Annals of Diagnostic Pathology, 2005; 9: 57-60.
8. 8. Lamboley JL, Crambert A, Le Moigne F, et al. A rare tumor: endometrial stromal nodule. J Radiol. 2010; 11:1161-1163.

9. 9. Baker P, Oliva E. Endometrial stromal tumours of the uterus: a practical approach using conventional morphology and ancillary techniques. J Clin Pathol 2007; 235-43.
10. 10. K. L. Chang, G.S. Crabtree, S. K. Lim- Tan, et al. Primary uterine endometrial stromal neoplasms. A clinicopathologic study of 117 cases. American Journal of Surgical Pathology, 1990; 14: 415-438.