THE ROLE OF ATYPICAL COLPOSCOPIC FINDINGS OF TRANSFORMATION ZONE IN LOCALIZING THE LESIONS

Abstract

140 cases in which the appereance of cerviz in gynecological examination is suspicious were included to this study, A simultaneous pap-smear with detailed cclposcopic examination was carried out on each case. Whenever the colposcopic anopearenco was abnormal and pap-smear was positive, a biopsy specimen was taken from the suspected area in 44 cases. Different surgical procedures were carried out to 11 of these cases. Colposcopic appearence, pap-smear, biopsy and the specimens from the surgical interventions were compared to find the correlation between the cervical epithelial pathology and atypia in colposcopic appereance. As a result, epitelial abnormality was shown mostly in the area characterized with vascular atypia among the other colposcopic examination findings (72,7 %).

Keywords

• Cx
• punch biopsy
• pap-smear colposcopy

LEZYON LOKALIZASYONLARINI BELIRBLEMEDE, _ TRANSFORMASYON ZONUNDAKI ATIPiIK KOLPOSKOPIK GORUNUMLERIN ONEMI

Abstract

Bu ¢caliyma kapsamina iinekolojik muayene ile servikste patoloji suphe edilcn 149 vaka dahil! edildi. Bu vakalara Pap-smear taramasiyla birlikte kapceml kolposkojik muayene yanildi. Mclooskopik gértinumleri stoheli ve smearleri pszitif vakalardan youlencivilmis 44 vakadan biycpsi alind:, Olsulardan toplam 11’ine cesitli cerrahi girisimleruygularnci Uolposkovik séxtintimierle, histcpetolojik conuclar: karsillastirlarck hangi atipik kolposkopik gértntiimin epitel patolojisini daha iyi yensittigéi arastirildi. Sonug¢ olarak atipik vaskularizasyonun diger kolposkonik gértintimler icerisinde epitel atipisini en fazla yansittigzi tesbit edildi (% 72.7).

Keywords

• Serviks
• punch biopsi
• pap-smear
• kolposkopi

References

1. 1.Abitol M Benjamin F Castillo N : Management of the abnormal cervical smear and carcinoma in situ of the cervix during pregnancy Am. J. Obstet Gynecol. 117, 904, 1973.
2. 2.Benedet JL Boyes DA Nichols TM Millner A : Colposcepic evaluation of pregnant patients with abnormal cervical smear Br. J. Obstet Gynecol. 84: 517, 1977.
3. 3.Benecet JL Anderson GH Boyes A: Colposcopic accuracy in the diagnosis of microinvasive and occult invasive carcinoma, cf the cervix, Obstet. Gynecol. 65, 557-1985.
4. 4.Burgherdt E: Kolposkopie Spezielle Zervix-Pathologie Lehrbuch und Atlas Burgherdt E. (ed) George Thieme Verlag Stuttgart-New York, D. 7000-Stuttgart 30 Germany, 1984.
5. 5.Burke L. Mathewes BE : Colposcopy in clinical practice Burke L. (ed). F.A. Davis Coucspany Philadelphia 1977.
6. 6.De Patriltic AD Townsend DE Morrow CP et. al. : Colpcscopic evaluation of the abnormal Papanicolaou tesi in pregnancy Am. J. Obstet Gynecol, 121, 441, 1975.
7. 7.Di Saia PJ Creasman TW : Colposcopy in Clinical Gynecologic Oncology Trumbold C led) The C.V. Mosby Company St. Louis Missouri 13-29, 1984. Giles JA Hudsoa E Crow J Williams D Walker P : Colposcopic assessment of the accurary of cervical cytclogy screening. Br. Med. J. 296, 1099, 1928, Homesley HD Jobson VW Reish RL: Use of colposcopically directed, four quandrant cervical biopsy by the colposcopy trainee, The Journal of Reproductive Medicine, 29, 311, 1984.
8. 8.Giles JA Hudsoa E Crow J Williams D Walker P : Colposcopic assessment of the accurary of cervical cytclogy screening. Br. Med. J. 296, 1099, 1928,

9. 9.Homesley HD Jobson VW Reish RL: Use of colposcopically directed, four quandrant cervical biopsy by the colposcopy trainee, The Journal of Reproductive Medicine, 29, 311, 1984.
10. 10.Jordan JA : Colpcscopy, in the diagnosis of cervical cancer and precancer, Clinics in Obstetrics and Gynecology, 12, 67, 1985.
11. 11.Kelley J Whitehouse HH Dillard EA : The colposcopy clinic in a residency training program five years experience with colposcopically directed biopsies followed by conization or hysterectomy The Journal of Reproductive Medicine, 28, 127, 1983.
12. 12.Krumholz BA Knapp RC : Colpossopic selection of biopsy sites Obstet. Gynecol. 39, 22, 1972.
13. 13.Limburgy H Saar H : Comparsion between cytology and colposcopy in the diagnosis of early cervical carcinoma Am. J. Obstet Gynecol 75, 1298, 1958.
14. 14.Lurain JR, Gallup DG : Management of abnormal Papanicolaou smears in pregnancy Obstet Gynecol. 53, 484, 1979.
15. 15.Lurain JR, Gallup DG : Management of abnormal Papanicolaou smears in pregnancy Obstet Gynecol. 53, 484, 1979.
16. 16.Mostafa AS Vasques H Masri R.: Indications for and experience with colposcopy in the management of neoplasia of cervix Surg. Gynecol. and Obstet. 145, 529, 1977
17. 17.Navratil E Burghardt E Basardi F Nash W : Simultaneous colposcopy and cyto- logy used in screening for carcinoma of the cervix Am. J. Obstet Gynecol. 73. 1292, 1958.
18. 18.Ostergard DR Gondos B : Out patient therapy of preinvasive carvical neoplasia : Selection of patients with the use of colposcopy Am. J, Obstet Gynecol., 115, 783, 1973.
19. 19.Ostergard DR Nieberg RK : Evaluation of abdominal cervical cytology during pregnancy with colposcopy Am. J. Obstet Gynecol. 134 : 756, 1979.
20. 20Rochelson B Krumholz BA :; The «unsatisfactory» colposcopic examination The Journal of Repdocductive Medicine, 28, 131, 1983.
21. 21.Rome RM Ucruyo R Nelson JH ; Observation on the surface area of the abnor- mal transformation zone associated with intraepithelial and early invasive squa- mous cell lesion of the cervix Am. J. Obstet. Gynecol,, 129, 565, 1977.
22. 22.Shingleton HM Gore H Austin JM : Outpatient evaluation of patients with atypical Papanicolaou smears : Contrubution of endocervical curretage Am. J. Obstet Gynecol. 126, 122, 1976.
23. 23.Stafl A Mattingly RF : Colposcopic diagnosis of cervical neoplasia, Obstet Gynecol. 41, 168, 1973.
24. 24.Stafl A : Colposcopic; in Obstetrics and Gynecol. Danforsth DN. (ed) J.B. Lippincott Company Philadelphia 1986, p. 1957.
25. 25.Stafl A Wilbanks GD : An international terminology of colposcopy : Report of nomenclature Comittee of the international Federation of cervical pathology and colposcopy Obstet. Gynecol. 77, 313. 1991.
26. 26.Tovell HMM Banogan P Nash AD : Cytology and colposcopy in the diagnosis and management of preclinical carcinoma of the cervix uteri: A learning experience Am. J. Obstet Gynecol 124, 924, 1976.
27. 27.Urcuyo R. Rome RM Nelson JH : Some observations on the value of endocervicalcurretage performed as an integral part of colposcopic examination of patients with abnormal cervical cytology Am. J. Obstet Gynecol .128, 787, 1981.
28. 28.Wilbanks GD : Cervical Intraepithelial Neoplasia in : Sciarra Gynecology and Obstetrics Sciarra JJ. (ed) Harper Row Publishers, Philadelphia. Vol : 4 Chap : 4 1986.
29. 29.Yavuz H : Kolposkopi-Kolpomikroskopi : Kadm Genital Kanserleri 118 - 129, Yargicoglu Matbaasi, Ankara, 1978.