The Effects of Recombinant Human Erythropoietin Therapy on Blood Pressure and Plasma Renin-Aldosteron Levels in Chronic Hemodialysis Patients
Abstract
Hypertension is one of the most commonly seen complications in chronic hemodialysis patients treated with recombinant human
erythropoietin. The pathogenesis of hypertension is unknown. Sixteen patients are included to this study. Blood pressures, hematocrit, plasma renin activity (PRA) and aldosterone levels was monitored during a 6 months period of treatment. Hematacrit levels were significantly
increased following treatment (p<0.001), but PRA and aldosterone levels remained unchanged (p>0.05).
Keywords
Hemodialysis, r-HuEPO therapy, Hypertension, Plasma renin activity, Aldosterone.
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