KAN-BEYİN BARİYERİ PERMEABİLİTE ARTIŞI MEKANİZMALARI

Erhan Nalçacı

EN TR

KAN-BEYİN BARİYERİ PERMEABİLİTE ARTIŞI MEKANİZMALARI

Abstract

Kan beyin bariyeri (KBB)nin proteinlere karşı permeabilitesinin çok düşük olduğu bilinmektedir. Bu düşük permeabilite; beyin kapiller endotel hücreleri arasında bulunan sıkı fenestraların yokluğuna ve pinositotik aktivitenin düşüklüğüne bağlanmıştır. Ancak iskemi, soğuk yaralanması, akut hipertansiyon ve konvülsiyonlar gibi patolojik olaylar esnasında KBB'i yıkılmaktadır. KBB'de proteinlere karşı artmış permeabilitedenj pinositotik aktivite artışı sorumlu tutulmuş ve histaminden araşidonik asit metabolizması ürünlerine kadar çeşitli faktörlerin rolü incelenmiştir. Sunulan derlemede, KBB permeabilite artışına yol açan, histamin salınımı, araşidonik asit metabolizması ve oksidan stres arasındaki ilişki tartışılmıştır.

Keywords

: Kan-beyin bariyeri, Pinositotik aktivite, histamin, oksidan stres, Drostaglandinler, hipertansiyon, epileptik atak.

References

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Details

Primary Language

Turkish

Subjects

Central Nervous System

Journal Section

Review

Authors

Erhan Nalçacı ^*
Türkiye

Publication Date

September 30, 1993

Submission Date

January 11, 1993

Acceptance Date

May 28, 1993

Published in Issue

Year 1993 Volume: 46 Number: 3

IZ

https://izlik.org/JA34FC89MS

APA

Nalçacı, E. (1993). KAN-BEYİN BARİYERİ PERMEABİLİTE ARTIŞI MEKANİZMALARI. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 46(3), 493-511. https://izlik.org/JA34FC89MS

AMA

1.Nalçacı E. KAN-BEYİN BARİYERİ PERMEABİLİTE ARTIŞI MEKANİZMALARI. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1993;46(3):493-511. https://izlik.org/JA34FC89MS

Chicago

Nalçacı, Erhan. 1993. “KAN-BEYİN BARİYERİ PERMEABİLİTE ARTIŞI MEKANİZMALARI”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 46 (3): 493-511. https://izlik.org/JA34FC89MS.

EndNote

Nalçacı E (September 1, 1993) KAN-BEYİN BARİYERİ PERMEABİLİTE ARTIŞI MEKANİZMALARI. Ankara Üniversitesi Tıp Fakültesi Mecmuası 46 3 493–511.

IEEE

[1]E. Nalçacı, “KAN-BEYİN BARİYERİ PERMEABİLİTE ARTIŞI MEKANİZMALARI”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 46, no. 3, pp. 493–511, Sept. 1993, [Online]. Available: https://izlik.org/JA34FC89MS

ISNAD

Nalçacı, Erhan. “KAN-BEYİN BARİYERİ PERMEABİLİTE ARTIŞI MEKANİZMALARI”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 46/3 (September 1, 1993): 493-511. https://izlik.org/JA34FC89MS.

JAMA

1.Nalçacı E. KAN-BEYİN BARİYERİ PERMEABİLİTE ARTIŞI MEKANİZMALARI. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1993;46:493–511.

MLA

Nalçacı, Erhan. “KAN-BEYİN BARİYERİ PERMEABİLİTE ARTIŞI MEKANİZMALARI”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 46, no. 3, Sept. 1993, pp. 493-11, https://izlik.org/JA34FC89MS.

Vancouver

1.Erhan Nalçacı. KAN-BEYİN BARİYERİ PERMEABİLİTE ARTIŞI MEKANİZMALARI. Ankara Üniversitesi Tıp Fakültesi Mecmuası [Internet]. 1993 Sep. 1;46(3):493-511. Available from: https://izlik.org/JA34FC89MS

KAN-BEYİN BARİYERİ PERMEABİLİTE ARTIŞI MEKANİZMALARI

The Permeahility Increase Mechanisms of Blood-Brain Barrier

Abstract

Keywords

KAN-BEYİN BARİYERİ PERMEABİLİTE ARTIŞI MEKANİZMALARI

Abstract

Keywords

References

Details

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Subjects

Journal Section

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Publication Date

Submission Date

Acceptance Date

Published in Issue

IZ

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