Abstract
Çalışmamızda A.Ü. İbni Sina Hastanesinde 1990 yılında çeşitli klinik materyallerden izole edilen 935 koagülaz pozitif, 582 koagülaz, negatif stafilokokun çeşitli antimikrobik ilaçlara karşı disk diffüzyon yöntemiyle duyarlılıkları araştırıldı. Çalışmada. kullanılan antibiyotikler, penisilin G, ampisilin, mezlosilin, amoksisilin --klavulanik asit, ampisilin -sulbaktam, sefalotin, sefaleksin, sefradin, sefuroksim, sefaklor, sefotaksim, sefoperazon, seftriakson, seftizoksim, seftazidim, amikasin, netilmisin, tobramisin, vankomisin, kloramfenikol, ko-trimoksazol, tetrasiklin, eritromisin, linkomisin, ofloksasin, siprofloksasindir. Vankomisin koagülaz pozitif ve negatif stafilokoklara “ 100-100 oranında, etkili bulundu. Vankomisinden sonra amoksisilin 4 kavulanik asit (94 98-97), ampisilin--sulbaktam (“2 98-94), ofloksasin (& 97-90), siprofloksasin (96 97-92), sefalotin (72 96-88), sefuroksim (96 94-84), sefotaksim (X 97-87), kloramfenikol (7 93-79), netilmisin (9 96-96), amikasin (9 94-89), en etkili antibiyotikler olarak bulundu.
Keywords
References
- 1. Archer GL : Staphylococcus eoidermidis and other coagulase negative staphylococci. Principles and Practice of Infectious Diseases, 3rd Edition (Ed : Mandell GL, Douglas RG, Bennet JE) da New York, Churchill-Livingstone, s : 1511, 1990.
- 2. Çetin ET Töreci K Badur S Erdeniz H : Muayene maddelerinden izole edilen bakterilerin bazı aminoglikozid, sefalosporin, penisilin grubu antibiyotiklere, beta-laktamaz inhibitörleri ile birlikte kullanılan penislinlere ve ofloksasine duyarlılıkları. ANKEM Dergisi 1 (4) ; 423-28, 1987.
- 3. Davies AJ : Coagulase negative staphylococcal infections. British Medical Journal Vol : 290. pp ; 1230-31, 1987,
- 4. Goldberg DM : The Cephalosporins. The Med. Clinics of North America Update on Antibiotics 1. Ed : Conover BA, W.B. Saunders Company West Washington Sguare, Philadelphia, Pennsylvania, Vol : 71, Num ; 6, 1113-1133, 1987,
- 5. Gün H Özinel MA Yenen OŞ : Klinik örneklerden izole edilen stafilokoklarda methicillin direnci. Türk Mikrobiyoloji Cem. Dergisi, 20 (3-4) : 211-215, 1990.
- 6. Hackbartı CJ and Chambers HF : Methicillin-Resistans Staphylococci : Detection Methods and Treatment of Infeciions. Antimicrobial Agents and Chemotherapi. Vol:33, No ; 7; 995-999, 1969.
- 7. Levine JF : Vancomycin. The Med. Clinics of North America Update on Antibiotics 1. Ed : Conover BA W.B. Saunders Company West Washington Sguare, Philadelphia, Pennsylvania, Vol : 71, Num : 6, 1135-45, 1987,
- 8. Moellering RC : Beta-lactamase Inhibition : Therapeutic Implications in Infecious Disease-an Överview. Reviews of Infectious Diseases vol ; 13 (suppl, 9) : s 723-6, 1991.
- 9. Moller JK : Observations on multiple drug resistance in coagulase negalive staphylococci isolated in hospitals from 1975 to 1985. J. Hosp. Infect. 11 : 26, 1988.
- 10. Noone P Sage R Guimaraes MA : The in vitro Activity ol Betalactam Antibiotics against Hospital Pathogens. Scand 1. Infect. Dis. 20 : 461, 1988,
- 11. Parry MF ; The penicillins. The Medical Clinics of North America Update on Antibiotics. 1. Ed : Conover B.A, W.B. Saunders Company West Washington Sguare, Philadelphia, Pennsylvania, Vol ; 7i, Num ; 6, 1093-1112. 1987,
- 12. Sultan N Türet S İmir T : Metisiline dirençli stafilokokların antibiotik dirençliliklerinin incelenmesi. Mikrobiyal Bult. 25 : 227-234, 1991.
- 13. Waldvogel FA : Staphylococcus aureus (including toxic shock syndrome). Principles and Practice of Infections Diseases, 3rd Edition (Ed : Mandell Gİ, Douglas RG, Bennet JE) da New York, Churchill-Livingstone, s : 1489, 1990,
Abstract
Mm this study, the invitro susceptibility of 935 coagulase positive and 582 coagulase negative staphylococci isolated from various clinical materials in University of Ankara, İbn-i Sina Hospital in 1990, were studied by disk diffusion method. The antibiotics used in this study are : Penicillin G, ampicillin, mezlocillin, amoxicillin-lavulanate, ampicillin-sulbactam, cephalothin, cephalexin, cephradine, cefuroxime, cefaclor, cefotaxime, cefoperazone, cefiriaxone, ceftizoxime, ceftazidime, amikacin, netilmicin, tobrambycin, vancomycin, chloramphenicol, cotrimoxazole, tetracyline, erytromycin, lincomycin, ofloxacin, and ciprofloxacin. Coagulase positive and coagulase negative staphylococci are 100 7 - 100 Ye susceptible to Vancomycin. The other antibiotics found to be effective against coagulase positive and coagulase negative staphylococci are : amoxicillin-clavulanate (98-97 ©), ampicillin-sulbactam (98-94 X), ofloxacin (97-90 ©), ciprofloxacin (97-92 ©), cephaelothin (96-38 72), cefuroxime (94-84 7), cefotaxime (97-387 “), chloramphenicol (93-79 ©), netilmicin (96-96 &) and amikacin (94-89 ©).
Keywords
References
- 1. Archer GL : Staphylococcus eoidermidis and other coagulase negative staphylococci. Principles and Practice of Infectious Diseases, 3rd Edition (Ed : Mandell GL, Douglas RG, Bennet JE) da New York, Churchill-Livingstone, s : 1511, 1990.
- 2. Çetin ET Töreci K Badur S Erdeniz H : Muayene maddelerinden izole edilen bakterilerin bazı aminoglikozid, sefalosporin, penisilin grubu antibiyotiklere, beta-laktamaz inhibitörleri ile birlikte kullanılan penislinlere ve ofloksasine duyarlılıkları. ANKEM Dergisi 1 (4) ; 423-28, 1987.
- 3. Davies AJ : Coagulase negative staphylococcal infections. British Medical Journal Vol : 290. pp ; 1230-31, 1987,
- 4. Goldberg DM : The Cephalosporins. The Med. Clinics of North America Update on Antibiotics 1. Ed : Conover BA, W.B. Saunders Company West Washington Sguare, Philadelphia, Pennsylvania, Vol : 71, Num ; 6, 1113-1133, 1987,
- 5. Gün H Özinel MA Yenen OŞ : Klinik örneklerden izole edilen stafilokoklarda methicillin direnci. Türk Mikrobiyoloji Cem. Dergisi, 20 (3-4) : 211-215, 1990.
- 6. Hackbartı CJ and Chambers HF : Methicillin-Resistans Staphylococci : Detection Methods and Treatment of Infeciions. Antimicrobial Agents and Chemotherapi. Vol:33, No ; 7; 995-999, 1969.
- 7. Levine JF : Vancomycin. The Med. Clinics of North America Update on Antibiotics 1. Ed : Conover BA W.B. Saunders Company West Washington Sguare, Philadelphia, Pennsylvania, Vol : 71, Num : 6, 1135-45, 1987,
- 8. Moellering RC : Beta-lactamase Inhibition : Therapeutic Implications in Infecious Disease-an Överview. Reviews of Infectious Diseases vol ; 13 (suppl, 9) : s 723-6, 1991.
- 9. Moller JK : Observations on multiple drug resistance in coagulase negalive staphylococci isolated in hospitals from 1975 to 1985. J. Hosp. Infect. 11 : 26, 1988.
- 10. Noone P Sage R Guimaraes MA : The in vitro Activity ol Betalactam Antibiotics against Hospital Pathogens. Scand 1. Infect. Dis. 20 : 461, 1988,
- 11. Parry MF ; The penicillins. The Medical Clinics of North America Update on Antibiotics. 1. Ed : Conover B.A, W.B. Saunders Company West Washington Sguare, Philadelphia, Pennsylvania, Vol ; 7i, Num ; 6, 1093-1112. 1987,
- 12. Sultan N Türet S İmir T : Metisiline dirençli stafilokokların antibiotik dirençliliklerinin incelenmesi. Mikrobiyal Bult. 25 : 227-234, 1991.
- 13. Waldvogel FA : Staphylococcus aureus (including toxic shock syndrome). Principles and Practice of Infections Diseases, 3rd Edition (Ed : Mandell Gİ, Douglas RG, Bennet JE) da New York, Churchill-Livingstone, s : 1489, 1990,
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Medical Bacteriology |
| Journal Section | Case Report |
| Authors | |
| Publication Date | September 30, 1992 |
| IZ | https://izlik.org/JA93ZL23BX |
| Published in Issue | Year 1992 Volume: 45 Issue: 3 |