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Geçici Fokal Serebran İskemi Sonrası İntra Arteriyel Mannitolum Etkisinin Araştırılması

Year 1991, Volume: 44 Issue: 3, 404 - 412, 30.09.1991

Ümit Kaya

Abstract

Geçici serebral iskemi oluşturulan tavşanlarda, iskemi sonrasında, resirkülasyonla beraber intra arteriyel olarak verilenManritol'ün iskemik bölge üzerine olan etkileri histopatolojik olarak ineçlenmiştir. Mannitol'ün iskemik perioddan sonra verilmesinin iskemiyi azaltıcı faydalı etkisi görülmüştür.

Keywords

Serebral iskemi Mannitol Resirkülasyon.

References

  • 1, Beck WD Hurt NM Hansen EK ; Effect of Intracarotit Hyperoşmolar Mannitol on Cerebral Cortical Arteries. A Morphometric Study : Stroke 18 : 1 : 134-136, 1984,
  • 2. Brown AW Brierley JB : Anoxic-Ischemic Cell Change in Rat Brain, A Light Microscopic and Fine Structural Observations, J. Neurol. Scan. 16 : 59-84, 1972.
  • 3. Jansen I Golman K Edvinson L : Mechanişm of Action of Contras Media on Cranial Vessels : Investigative Radiology 22 ; 814-821, 1987,
  • 4, Jenkins LM Powlishock JT Lewelt W et al : The Role of Post Ischemic Recirculation in the Development of Ischemic Noronal Mmjury Following Complete Cerebral Ischemia. Acta Neuropathalogy 55 ; 205-220, 1981,
  • 5. Hanamura T Asano T Shigeno T et al : How Dose Mannitol Reduce Edema Water in Focal Cerebral Ischemia? In Miller J,D., Teasdale G.M,, Rowan J.O,, Galbraith S.L., Mendelow A.D., (eds). Intracranial Pressure VI, Springer-Verlag, Berlin/Heidelberg. 19886 pp : 577-580.
  • 6. Hoft JT : Cerebral Protection, J. Neurosurgery. 65 : 579-591, 1986.
  • 7. İanotti F Hoff JT : İschemie Brain with and without Reperfusion : An Experimental Study in Gerhbils. Stroke 14 : 562-567, 1983.
  • 8. İmaizumi $ Kayama T Suzuki J et al : Chemiluminesscence in Hypoxic Brain : Correlation between Energy Metabolism and Free Radical Reaction. Stroke, 1061-1065, 1984.
  • 9. Kelimo H and Smith LM : Structural Aspects of Ischemic Brain Damage. Acta Neurochurirgia 36 ; 129-132, 1986.
  • 10. Kassel NE Bauman KW Hitchan PW et al : Influence of a Continous Hihg Dose of Infusion of Mamnitol on Cerebral Blood Flow in Normal Dogs. Neurosurgery 9 : 283-286, 1981.
  • 11. Little JR O'shaughnessy D : Treatment of Acute Focal Ischemia, with Continous CSF Drainage and Mannitol! : Stroke, 10 ; 4 ; 446-449, 1979.
  • 12. Little JR : Microvascular Alterations and Edema in Focal Cerebral Ischemia. In Papius. H. Feindel W. (eds) Dynamies of Brain Edema. New York, Springer Verlag 1976; pp : 236-243
  • 13. Litle JR : Medification of Acute Focal Ischemia, by Treatment with Mannitol. Siroke 9: 4-9, 1978,
  • 14. Manninen PH Low HA Gelb A Brown S : The Effect ol High Dose Mannitol on Serum and Urine Eeletrolytes and Osmolality in Neurosurgical Patent : Can. J. Anaesth. 37 : 5 : 442-46, 1987,
  • 15. Marshall LF Smith RW Fausher LA Shopiro HM : Mannitol Dose Reguirement$ in Brain Injured Patients. J. Neurosur. 48 : 169-172, 1978.
  • 16. Meyer FB Anderson ER Sundt T Yaksh T ;: Treatment of Experimental Focal Cerebral Ishemi with Mannitol, J. Neurosurg. 66 ; 109-115, 1987.
  • 17. Muizelaar JP Wei EP Kontos HA Berker DP ; Intravenous Mannitol Cause a Frofound Cerehbral Vasoconsiriction. Stroke 14 : 125, 1983.
  • 18. Ostensen J Bugge FJ Stokke SE Langber H Kill F ; Mechanism of Osmotic Diuresis Studies by Imfusion of NaHCO3 and Mannitol in Dogs. Acta Physiol, Scan. 131 : 397-400, 1987.
  • 19. Salahhuddin TS Johansson BB Kalimo H Olsson BY : Structural Changes in the Rat Brain after Carotit Infussion of Hyperosmolar Solutions : A Light Mic-- roscopic and Immunohistochemica! Study, Neuropathology and Applied Neurobiology, 14 : 467-482, 1988.
  • 20. Solman WER Spetzler FR : Therapeutits for Focal Cerebral Ischemia, Neuroşur- * gory 6 :4 ; 446-452, 1980.
  • 21. Speck U Press WR Mütsel W : Osmo'ality-Related Effects of İnjections into ihe Central Nervous System : Investigative Radiology :23:1: 144-117. 1988.
  • 22. Suzuki J Abike 1 Mizol K Oba M Yashimoto T : Protective Effects of Phenyyoin and its Enchanced Action by Combimned Administration with Mannitol and Vitamine E in Corobral Iscehemia, Aciz Neurochirurgica 88 : 56-64, 1987.
  • 23. Takayasu M Dacey AG : Etfecis of Mannitol on Mmtracerebral Arteriolar Diameter in Vitro ; Extra-Luminal and Intraluminal Application. Neurosurgery 26 : 5: 747-752, 1989,
  • 24. Tanaka A Tomonaga M : Effects ol Mannitol on Cerebral Blood Flow and Microcirculation during Experimental Middle Cerebral Artery Oçgclusion. Surg. Neurol, 28 : 189-195, 1987.

Investıgatıon Of The Effect Of Intra-Arterıal Mannıtolum After Transıtıonal Focal Cerebral Ischemıa

Year 1991, Volume: 44 Issue: 3, 404 - 412, 30.09.1991

Ümit Kaya

Abstract

The effect of intra arterialiy Mannitol perfusion starting with the repertusion of focal cerebral ischemic rabbits for four hours duration are evaluated histopatologically, Mannitol administered after the ischemic period is found to be of benefical effect in reducing ischemic lesion.

Keywords

Cerebral ischemia Mannitol Recirculation.

References

  • 1, Beck WD Hurt NM Hansen EK ; Effect of Intracarotit Hyperoşmolar Mannitol on Cerebral Cortical Arteries. A Morphometric Study : Stroke 18 : 1 : 134-136, 1984,
  • 2. Brown AW Brierley JB : Anoxic-Ischemic Cell Change in Rat Brain, A Light Microscopic and Fine Structural Observations, J. Neurol. Scan. 16 : 59-84, 1972.
  • 3. Jansen I Golman K Edvinson L : Mechanişm of Action of Contras Media on Cranial Vessels : Investigative Radiology 22 ; 814-821, 1987,
  • 4, Jenkins LM Powlishock JT Lewelt W et al : The Role of Post Ischemic Recirculation in the Development of Ischemic Noronal Mmjury Following Complete Cerebral Ischemia. Acta Neuropathalogy 55 ; 205-220, 1981,
  • 5. Hanamura T Asano T Shigeno T et al : How Dose Mannitol Reduce Edema Water in Focal Cerebral Ischemia? In Miller J,D., Teasdale G.M,, Rowan J.O,, Galbraith S.L., Mendelow A.D., (eds). Intracranial Pressure VI, Springer-Verlag, Berlin/Heidelberg. 19886 pp : 577-580.
  • 6. Hoft JT : Cerebral Protection, J. Neurosurgery. 65 : 579-591, 1986.
  • 7. İanotti F Hoff JT : İschemie Brain with and without Reperfusion : An Experimental Study in Gerhbils. Stroke 14 : 562-567, 1983.
  • 8. İmaizumi $ Kayama T Suzuki J et al : Chemiluminesscence in Hypoxic Brain : Correlation between Energy Metabolism and Free Radical Reaction. Stroke, 1061-1065, 1984.
  • 9. Kelimo H and Smith LM : Structural Aspects of Ischemic Brain Damage. Acta Neurochurirgia 36 ; 129-132, 1986.
  • 10. Kassel NE Bauman KW Hitchan PW et al : Influence of a Continous Hihg Dose of Infusion of Mamnitol on Cerebral Blood Flow in Normal Dogs. Neurosurgery 9 : 283-286, 1981.
  • 11. Little JR O'shaughnessy D : Treatment of Acute Focal Ischemia, with Continous CSF Drainage and Mannitol! : Stroke, 10 ; 4 ; 446-449, 1979.
  • 12. Little JR : Microvascular Alterations and Edema in Focal Cerebral Ischemia. In Papius. H. Feindel W. (eds) Dynamies of Brain Edema. New York, Springer Verlag 1976; pp : 236-243
  • 13. Litle JR : Medification of Acute Focal Ischemia, by Treatment with Mannitol. Siroke 9: 4-9, 1978,
  • 14. Manninen PH Low HA Gelb A Brown S : The Effect ol High Dose Mannitol on Serum and Urine Eeletrolytes and Osmolality in Neurosurgical Patent : Can. J. Anaesth. 37 : 5 : 442-46, 1987,
  • 15. Marshall LF Smith RW Fausher LA Shopiro HM : Mannitol Dose Reguirement$ in Brain Injured Patients. J. Neurosur. 48 : 169-172, 1978.
  • 16. Meyer FB Anderson ER Sundt T Yaksh T ;: Treatment of Experimental Focal Cerebral Ishemi with Mannitol, J. Neurosurg. 66 ; 109-115, 1987.
  • 17. Muizelaar JP Wei EP Kontos HA Berker DP ; Intravenous Mannitol Cause a Frofound Cerehbral Vasoconsiriction. Stroke 14 : 125, 1983.
  • 18. Ostensen J Bugge FJ Stokke SE Langber H Kill F ; Mechanism of Osmotic Diuresis Studies by Imfusion of NaHCO3 and Mannitol in Dogs. Acta Physiol, Scan. 131 : 397-400, 1987.
  • 19. Salahhuddin TS Johansson BB Kalimo H Olsson BY : Structural Changes in the Rat Brain after Carotit Infussion of Hyperosmolar Solutions : A Light Mic-- roscopic and Immunohistochemica! Study, Neuropathology and Applied Neurobiology, 14 : 467-482, 1988.
  • 20. Solman WER Spetzler FR : Therapeutits for Focal Cerebral Ischemia, Neuroşur- * gory 6 :4 ; 446-452, 1980.
  • 21. Speck U Press WR Mütsel W : Osmo'ality-Related Effects of İnjections into ihe Central Nervous System : Investigative Radiology :23:1: 144-117. 1988.
  • 22. Suzuki J Abike 1 Mizol K Oba M Yashimoto T : Protective Effects of Phenyyoin and its Enchanced Action by Combimned Administration with Mannitol and Vitamine E in Corobral Iscehemia, Aciz Neurochirurgica 88 : 56-64, 1987.
  • 23. Takayasu M Dacey AG : Etfecis of Mannitol on Mmtracerebral Arteriolar Diameter in Vitro ; Extra-Luminal and Intraluminal Application. Neurosurgery 26 : 5: 747-752, 1989,
  • 24. Tanaka A Tomonaga M : Effects ol Mannitol on Cerebral Blood Flow and Microcirculation during Experimental Middle Cerebral Artery Oçgclusion. Surg. Neurol, 28 : 189-195, 1987.
There are 24 citations in total.

Details

Primary Language English
Subjects Brain and Nerve Surgery (Neurosurgery)
Journal Section Research Article
Authors

Ümit Kaya

Publication Date September 30, 1991
Published in Issue Year 1991 Volume: 44 Issue: 3

Cite

APA Kaya, Ü. (1991). Investıgatıon Of The Effect Of Intra-Arterıal Mannıtolum After Transıtıonal Focal Cerebral Ischemıa. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 44(3), 404-412.
AMA Kaya Ü. Investıgatıon Of The Effect Of Intra-Arterıal Mannıtolum After Transıtıonal Focal Cerebral Ischemıa. Ankara Üniversitesi Tıp Fakültesi Mecmuası. September 1991;44(3):404-412.
Chicago Kaya, Ümit. “Investıgatıon Of The Effect Of Intra-Arterıal Mannıtolum After Transıtıonal Focal Cerebral Ischemıa”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 44, no. 3 (September 1991): 404-12.
EndNote Kaya Ü (September 1, 1991) Investıgatıon Of The Effect Of Intra-Arterıal Mannıtolum After Transıtıonal Focal Cerebral Ischemıa. Ankara Üniversitesi Tıp Fakültesi Mecmuası 44 3 404–412.
IEEE Ü. Kaya, “Investıgatıon Of The Effect Of Intra-Arterıal Mannıtolum After Transıtıonal Focal Cerebral Ischemıa”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 44, no. 3, pp. 404–412, 1991.
ISNAD Kaya, Ümit. “Investıgatıon Of The Effect Of Intra-Arterıal Mannıtolum After Transıtıonal Focal Cerebral Ischemıa”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 44/3 (September1991), 404-412.
JAMA Kaya Ü. Investıgatıon Of The Effect Of Intra-Arterıal Mannıtolum After Transıtıonal Focal Cerebral Ischemıa. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1991;44:404–412.
MLA Kaya, Ümit. “Investıgatıon Of The Effect Of Intra-Arterıal Mannıtolum After Transıtıonal Focal Cerebral Ischemıa”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 44, no. 3, 1991, pp. 404-12.
Vancouver Kaya Ü. Investıgatıon Of The Effect Of Intra-Arterıal Mannıtolum After Transıtıonal Focal Cerebral Ischemıa. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1991;44(3):404-12.