Ventricular Arrhythmia With Cessation of Infliximab in a Patient With Ankylosing Spondylitis

Year 2015, Volume: 68 Issue: 2, 77 - 79, 14.10.2015

Özgür Ulaş Özcan , Didem Sezgin Özcan Cemile Sevgi Polat , Nil Özyüncü , Çetin Erol

https://izlik.org/JA45RT62ZY

Abstract

Infliximab is an anti-tumor necrosis factor alpha agent, which is indicated for the treatment of resistant ankylosing spondylitis (AS). We presented a patient with AS who developed ventricular tachycardia after premature cessation of infliximab. Ventricular tachycardia did not recur after restarting of infliximab treatment. This case report remarked the significance of the suppression of inflammation in AS since the subclinical ventricular involvement may potentially lead to the fatal arrhythmias.

Keywords

Arrhythmia , Arthritis , Seronegative Spondyloarthropathy , Syncope , Tumor Necrosis Factor Alpha

Ethical Statement

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Ankilozan Spondilitli Bir Hastada İnfliksimabın Kesilmesiyle Olușan Ventriküler Aritmi

https://izlik.org/JA45RT62ZY

Abstract

İnfliksimab dirençli ankilozan spondilit (AS) tedavisinde endikasyonu bulunan bir anti-tümör nekroz faktör alfa ajanıdır. İnfliksimabın erken kesilmesi sonucu ventriküler tașikardi gelișen bir hasta sunuyoruz. İnfliksimab tedavisinin tekrar bașlanmasıyla ventriküler tașikardi tekrarlamamıștır. Bu vaka takdimi AS hastalarında inflamasyonun, subklinik ventriküler tutulumun potansiyel olarak ölümcül aritmilere yol açabilmesi nedeniyle, baskılanmasının önemini vurgulamaktadır.

Keywords

Aritmi , Artrit , Senkop , Seronegatif Spondiloartropati , Tümör Nekroz Faktör Alfa

Ethical Statement

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Supporting Institution

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