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AKUT LOSEMILERDE IMMUNFENOTIPLENDIRME

Year 1990, Volume: 43 Issue: 4, 915 - 924, 31.12.1990

Abstract

35 Acute Leukemia cases followed in our Department were classified by Immunophenotyping. The cases were classified as 13 ALL, 17 ANLL and 5 undifferentiated Acute Leukemia. Further classification revealed that ALL cases could be subdivided as 7 Non-T ALL, 4 T-ALL, 1 prolymphocytic leukemia and one Natural Killer leukemia. Immu-
nophenotyping was clearly helpful in determining the monocytic component in ANLL. In Acute Leukemia cases where conventional methods failed to reveal any leukemia typing, immunophenotyping has been found to be successful.

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References

  • 1. Ball ED Fouger WW : The expression of myeloid spesific antigens on myeloid cells : Correlations with leukemia subclasses and implications for normal myeloid differentiation. Blood 61 : 456-463, 1983.
  • 2. Ben-Bassat I Gale RP : Hybrid acute leukemia. Leukemia Res 8 : 919-936, 1984.
  • 3. Bennett JM Catovsky D Daniel MT et al: Proposals for the classification of acute leukemias. French-American-British (FAB) Cooperative Group. Br J Haematol 33 : 451-458, 1976.
  • 4. Campos L Guyotat D Archimbaud E et al: Surface marker expression in adult acute myeloid leukemia : correlations with initial characteristics, morphology and response to therapy. Br J Haematol 72 : 161-166, 1989.
  • 5. Catovsky D : The classification of AML. Diploma in Haematology, course notes 1988-1989,
  • 6. Chan LC Pegram SM Graeves MF : Contribution of immunophenotype to the classification of acute leukemia. Lancet 1: 475, 1985.
  • 7. First MIC : Cooperative Study Group. Morphologic, immunologic and cytogene- tic 10. (MIC) working classification in acute lymphoblastic leukemias. Cancer Genet Cytogenet 23 : 189-197, 1986.
  • 8. Foon KA Todd RF : Immunologic classification of Leukemia and Lymphoma. Blood 68(1) ; 1-31, 1986,
  • 9. Kaplan SS Penchansky L Stolc V et al : Immunophenotyping in the classifica- tion of acute leukemia in adults. Cancer 63 : 1510-1527, 1989,
  • 10. Kohler G Nobel Lecture : Derivation and diversification of monoclonal antibodies. Bioscience Report 5 : 535-549, 1985

Akut Lösemilerde Immünfenotiplendirme

Year 1990, Volume: 43 Issue: 4, 915 - 924, 31.12.1990

Abstract

Bu calismamizda bilim dalimizda izlenen 35 akut lo6semi olgusun immunfenotiplendirme ile lésemi sınıflandırmasi sunulmuştur. Olgularimiz immunfenoiiplendirme sonucunda 13’ ALL, 17’si ANLL ve 5 siniflandinlamayan Akut Lésemi olarak degerlendirilmistir. ALL olgularinin 7’si Non-T’ ALL, 4’ T-ALL, 1 prolenfositik lésemi ve 1’i de
Natural Killer lésemi olarak degerlendirilmistir. ANLL olgularinda ise Ozellikle monositer komponenti ayirdetmede immunfenotiplendirmenin belirgin yarar: oldugu izlenmistir. Konvansiyonel yontemlerle siniflandirma yapilamayan Akut Lésemi olgularinda immunfenotiplendirme ile ayırım yapılabilmiştir.

Ethical Statement

-

Supporting Institution

-

Project Number

-

Thanks

-

References

  • 1. Ball ED Fouger WW : The expression of myeloid spesific antigens on myeloid cells : Correlations with leukemia subclasses and implications for normal myeloid differentiation. Blood 61 : 456-463, 1983.
  • 2. Ben-Bassat I Gale RP : Hybrid acute leukemia. Leukemia Res 8 : 919-936, 1984.
  • 3. Bennett JM Catovsky D Daniel MT et al: Proposals for the classification of acute leukemias. French-American-British (FAB) Cooperative Group. Br J Haematol 33 : 451-458, 1976.
  • 4. Campos L Guyotat D Archimbaud E et al: Surface marker expression in adult acute myeloid leukemia : correlations with initial characteristics, morphology and response to therapy. Br J Haematol 72 : 161-166, 1989.
  • 5. Catovsky D : The classification of AML. Diploma in Haematology, course notes 1988-1989,
  • 6. Chan LC Pegram SM Graeves MF : Contribution of immunophenotype to the classification of acute leukemia. Lancet 1: 475, 1985.
  • 7. First MIC : Cooperative Study Group. Morphologic, immunologic and cytogene- tic 10. (MIC) working classification in acute lymphoblastic leukemias. Cancer Genet Cytogenet 23 : 189-197, 1986.
  • 8. Foon KA Todd RF : Immunologic classification of Leukemia and Lymphoma. Blood 68(1) ; 1-31, 1986,
  • 9. Kaplan SS Penchansky L Stolc V et al : Immunophenotyping in the classifica- tion of acute leukemia in adults. Cancer 63 : 1510-1527, 1989,
  • 10. Kohler G Nobel Lecture : Derivation and diversification of monoclonal antibodies. Bioscience Report 5 : 535-549, 1985
There are 10 citations in total.

Details

Primary Language Turkish
Subjects Oncology and Carcinogenesis (Other)
Journal Section Research Article
Authors

Hamdi Akan

Project Number -
Publication Date December 31, 1990
Published in Issue Year 1990 Volume: 43 Issue: 4

Cite

APA Akan, H. (1990). Akut Lösemilerde Immünfenotiplendirme. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 43(4), 915-924.
AMA Akan H. Akut Lösemilerde Immünfenotiplendirme. Ankara Üniversitesi Tıp Fakültesi Mecmuası. December 1990;43(4):915-924.
Chicago Akan, Hamdi. “Akut Lösemilerde Immünfenotiplendirme”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 43, no. 4 (December 1990): 915-24.
EndNote Akan H (December 1, 1990) Akut Lösemilerde Immünfenotiplendirme. Ankara Üniversitesi Tıp Fakültesi Mecmuası 43 4 915–924.
IEEE H. Akan, “Akut Lösemilerde Immünfenotiplendirme”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 43, no. 4, pp. 915–924, 1990.
ISNAD Akan, Hamdi. “Akut Lösemilerde Immünfenotiplendirme”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 43/4 (December1990), 915-924.
JAMA Akan H. Akut Lösemilerde Immünfenotiplendirme. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1990;43:915–924.
MLA Akan, Hamdi. “Akut Lösemilerde Immünfenotiplendirme”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 43, no. 4, 1990, pp. 915-24.
Vancouver Akan H. Akut Lösemilerde Immünfenotiplendirme. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1990;43(4):915-24.