Research Article

In Synovial Fluid, İmmun Complex, Beta-2 Microglobulin Rheumatoid Factor And İmmunglobulin Levels İn Rheumatoid Arthritis

Volume: 39 Number: 4 December 31, 1986
Nurşen Düzgün *
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In Synovial Fluid, İmmun Complex, Beta-2 Microglobulin Rheumatoid Factor And İmmunglobulin Levels İn Rheumatoid Arthritis

Abstract

In this study immune complexes, beta-2 microglobulin, rheuma toid factor and immunglobulin levels (IgG, IgA, IgM) in synoviyal fluids have been detected in 37 patients with rheumatoid arthritis and 9 patients with non rheumatoid arthritis as control.The ratio of positivity of rheumatoid factor in synovial fluids in rheumatoid arthritis was % 67.5, This value was % 66 in non rheumatoid patients.We didn't find any difference in the means of immune complexes and immunglobulin levels in both groups. But a significant difference was observed in the beta-2 microglobulin levels in rheumatoid patients. It is suggested beta-2 microglobulin levels in synovial fluids may be helper criterium in the diagnosis of rheumatoid arthritis.

Keywords

rheuma, synovial, arthritis, immonglobulin

References

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  2. 2. Becker W., Parp W. ve ark. Z. Klin. Chem. 6 : 113, 1970.
  3. 3. Birch R.E., Fager M.W., Bernzier G.M. : Beta-2 mikroglobulin enhances human lymphocyte surface receptor expression for IgG. J. immun. 122 : 997, 1979.
  4. 4. Boyle J.A„ Buchanan W.W. : Clinical Rheumatology. First edition. Blacwell Scientific Publications. Oxford and Edinburg, 1971.
  5. 5. Cats A, Hazevoet H.M. : Significance of positive tests for rheumatoid factor in the prognosis of rheumatoid arthritis. Ann. Rheum. Dis 29 : 254, 1970. 6. Cracchiolo A., Goldberg Ll., Barnett E.V. : Studied of cryoprecipitates from synovial fluid of rheumatoid patients. Arth. and Rheumatism. 13/6 : 897, 1970.
  6. 7. Digeon M., Laver M. ve ark. : Detection of circulating immun complexes in human sera by simplified assaays with polyethylene glycol. J. of Immunolo gical methods. 16 : 165, 1977.
  7. 8. Freedman, G. Clinical Immunology Second. edition. 295. 1976.
  8. 9. Ghose T., Woodbury J.F.L. : Immünopathological changes, in rheumatoid' arthritis and other joint disease. J. Clin. Path. 28/2 : 109-117, 1975.
  9. 10. Hasler F., Stojan B. : Immunologische befunda im serum and in der gelenkflussigkeit bei patienten mit Rheumatoider Arthritis. 89/21 : 713-716, 1977. Il. Manicourt D, Brauman Fl., Orloff S. : Synovial fluid beta-2 microglobulin and hydroxproline fractions in rheumatoid arthritis and nonautoimmune arthropathies. Ann. Rheum. Dis. 39 : 207, 1980.
  10. 12. Roitt I. : Essential Immunology fourth edition, Black well seintific publications. 1978.

Details

Primary Language

English

Subjects

Immunology (Other), ​Internal Diseases

Journal Section

Research Article

Authors

Publication Date

December 31, 1986

Submission Date

October 1, 1986

Acceptance Date

December 30, 1986

Published in Issue

Year 1986 Volume: 39 Number: 4

IZ

https://izlik.org/JA45AB92NJ

Cite

RIS / Bibtex
APA
Düzgün, N. (1986). In Synovial Fluid, İmmun Complex, Beta-2 Microglobulin Rheumatoid Factor And İmmunglobulin Levels İn Rheumatoid Arthritis. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 39(4), 319-330. https://izlik.org/JA45AB92NJ
AMA
1.Düzgün N. In Synovial Fluid, İmmun Complex, Beta-2 Microglobulin Rheumatoid Factor And İmmunglobulin Levels İn Rheumatoid Arthritis. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1986;39(4):319-330. https://izlik.org/JA45AB92NJ
Chicago
Düzgün, Nurşen. 1986. “In Synovial Fluid, İmmun Complex, Beta-2 Microglobulin Rheumatoid Factor And İmmunglobulin Levels İn Rheumatoid Arthritis”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 39 (4): 319-30. https://izlik.org/JA45AB92NJ.
EndNote
Düzgün N (December 1, 1986) In Synovial Fluid, İmmun Complex, Beta-2 Microglobulin Rheumatoid Factor And İmmunglobulin Levels İn Rheumatoid Arthritis. Ankara Üniversitesi Tıp Fakültesi Mecmuası 39 4 319–330.
IEEE
[1]N. Düzgün, “In Synovial Fluid, İmmun Complex, Beta-2 Microglobulin Rheumatoid Factor And İmmunglobulin Levels İn Rheumatoid Arthritis”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 39, no. 4, pp. 319–330, Dec. 1986, [Online]. Available: https://izlik.org/JA45AB92NJ
ISNAD
Düzgün, Nurşen. “In Synovial Fluid, İmmun Complex, Beta-2 Microglobulin Rheumatoid Factor And İmmunglobulin Levels İn Rheumatoid Arthritis”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 39/4 (December 1, 1986): 319-330. https://izlik.org/JA45AB92NJ.
JAMA
1.Düzgün N. In Synovial Fluid, İmmun Complex, Beta-2 Microglobulin Rheumatoid Factor And İmmunglobulin Levels İn Rheumatoid Arthritis. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1986;39:319–330.
MLA
Düzgün, Nurşen. “In Synovial Fluid, İmmun Complex, Beta-2 Microglobulin Rheumatoid Factor And İmmunglobulin Levels İn Rheumatoid Arthritis”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 39, no. 4, Dec. 1986, pp. 319-30, https://izlik.org/JA45AB92NJ.
Vancouver
1.Nurşen Düzgün. In Synovial Fluid, İmmun Complex, Beta-2 Microglobulin Rheumatoid Factor And İmmunglobulin Levels İn Rheumatoid Arthritis. Ankara Üniversitesi Tıp Fakültesi Mecmuası [Internet]. 1986 Dec. 1;39(4):319-30. Available from: https://izlik.org/JA45AB92NJ