LIGHT MICROSCOPE INVESTIGATION OF THE EFFECTS OF DIETHYLSTILBESTOL ON RAT TEST

Belgin Can

LIGHT MICROSCOPE INVESTIGATION OF THE EFFECTS OF DIETHYLSTILBESTOL ON RAT TEST

Abstract

This study is concerned with the morphological changes observed in rat testicular tissue following diethylstilbestrol administration. While there wasn't any change in the control group, in the light microscopic examination of the group to which diethystilbestrol was given, the most important changes observed were; a) Atropy of the gonads, b) Thickening of tunica albuginea, c) Narrowing of seminiferous tubular wall and decreasing of tubuli diameters, d) Extensive fibrosis of the peritubular tissue, e) Marked increase in thickness and infolding of basement membrane, f) Dissociation and desquamation of spermatogenic epithelium, g) A gradual disappearance of spermatonic elements, h) Structural changes of Sertoli and Leydig cells. Consequently, after the administration of therapeutic dosage of diethylstilbestrol it was seen that the spermatogenesis was stoppedn the second phase, «Meiosis. On the light of this study, it is believed that further investigationby means of electron microscopy should be carried out for seeing fine structure.

Keywords

Testes, Diethylstilbestrol, RAT TEST

References

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Details

Primary Language

English

Subjects

Histology and Embryology

Journal Section

Research Article

Authors

Belgin Can ^*
Türkiye

Publication Date

June 3, 1994

Submission Date

January 1, 1994

Acceptance Date

March 31, 1994

Published in Issue

Year 1994 Volume: 47 Number: 1

IZ

https://izlik.org/JA43XE48PD

APA

Can, B. (1994). LIGHT MICROSCOPE INVESTIGATION OF THE EFFECTS OF DIETHYLSTILBESTOL ON RAT TEST. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 47(1), 85-94. https://izlik.org/JA43XE48PD

AMA

1.Can B. LIGHT MICROSCOPE INVESTIGATION OF THE EFFECTS OF DIETHYLSTILBESTOL ON RAT TEST. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1994;47(1):85-94. https://izlik.org/JA43XE48PD

Chicago

Can, Belgin. 1994. “LIGHT MICROSCOPE INVESTIGATION OF THE EFFECTS OF DIETHYLSTILBESTOL ON RAT TEST”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 47 (1): 85-94. https://izlik.org/JA43XE48PD.

EndNote

Can B (June 1, 1994) LIGHT MICROSCOPE INVESTIGATION OF THE EFFECTS OF DIETHYLSTILBESTOL ON RAT TEST. Ankara Üniversitesi Tıp Fakültesi Mecmuası 47 1 85–94.

IEEE

[1]B. Can, “LIGHT MICROSCOPE INVESTIGATION OF THE EFFECTS OF DIETHYLSTILBESTOL ON RAT TEST”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 47, no. 1, pp. 85–94, June 1994, [Online]. Available: https://izlik.org/JA43XE48PD

ISNAD

Can, Belgin. “LIGHT MICROSCOPE INVESTIGATION OF THE EFFECTS OF DIETHYLSTILBESTOL ON RAT TEST”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 47/1 (June 1, 1994): 85-94. https://izlik.org/JA43XE48PD.

JAMA

1.Can B. LIGHT MICROSCOPE INVESTIGATION OF THE EFFECTS OF DIETHYLSTILBESTOL ON RAT TEST. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1994;47:85–94.

MLA

Can, Belgin. “LIGHT MICROSCOPE INVESTIGATION OF THE EFFECTS OF DIETHYLSTILBESTOL ON RAT TEST”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 47, no. 1, June 1994, pp. 85-94, https://izlik.org/JA43XE48PD.

Vancouver

1.Belgin Can. LIGHT MICROSCOPE INVESTIGATION OF THE EFFECTS OF DIETHYLSTILBESTOL ON RAT TEST. Ankara Üniversitesi Tıp Fakültesi Mecmuası [Internet]. 1994 Jun. 1;47(1):85-94. Available from: https://izlik.org/JA43XE48PD