Hiperbilirubinemili Yenidoğanlarda Beyinsapı Uyarılmış İşitsel Potansiyellerdeki Değişiklikler

Year 1992, Volume: 45 Issue: 2, 271 - 278, 30.06.1992

Nihal Oygur

Abstract

İndirekt bilirubin seviyesi kan değişim sınırlarının altında olan 20 hiperbilirubinemili ve kontrol grubu olarak alınan 10 sağlıklı yenidoğana Beyinsapı Uyarılmış Potansjy'el yöntemi uygulanarak bilirubinin işitsel yollardaki ototoksik etkisi araştırıldı Olgularda I, ill ve V. dalga pik. latanslaxı, IIİ--V, İ-V interpik latansları ve beyinsapı iletim zamanında belirgin uzama saptandı. Dalga amplitüdleri açısından gruplar arasında fark gözlenmedi. Bilirubinin hem periferik hem de santral işitme yollarında toksik etkili oldüğü gösterildi.

Keywords

Sarılık , Yenicloğan , BSUİP

Project Number

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Changes In Braınstem Evoked Audıtory Potentıals In Newborns Wıth Hyperbılırubınemıa

Abstract

Changes In The Auditory Brainstem Responses In Newborns With Hypcrbilirubinemia The ototoxic effect of bilirubin on the auditory pathways were investigated by recording brainstem auditory evoked potentials in 20 neonates with indirect bilirubin levels less than the levels of exchange transfusion. Ten healthy neonates werè taken as control. Hyperbilirubinemic newborns showed prolonged peak latencies of waves I, Ill, V and interpeak latencies of waves Ill-V, I-V. Brainstem transmission time was also prolonged in jaundiced infants. The amplitudes between the jaundiced and the control groups did not dif fer significantly. It was found that bilirubin showed its toxic effect both in the peripheral and in brainstem pathways.

Keywords

Jaundice , Neonatal , BSUİP

Ethical Statement

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Supporting Institution

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Project Number

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Thanks

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References

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