Research Article
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Year 2023, Volume: 76 Issue: 3, 278 - 286, 30.06.2024
https://doi.org/10.4274/atfm.galenos.2023.26566

Abstract

References

  • 1. Ramanujam PS, Prasad ML, Abcarian H, Tan AB. Perianal abscesses and fistulas. A study of 1023 patients. Dis Colon Rectum. 1984;27:593-597.
  • 2. Garg P. Comparing existing classifications of fistula-in-ano in 440 operated patients: Is it time for a new classification? A Retrospective Cohort Study. Int J Surg. 2017;42:34-40.
  • 3. Abcarian H. Anorectal infection: abscess-fistula. Clin Colon Rectal Surg. 2011;24:14-21.
  • 4. Fung AK, Card GV, Ross NP, et al. Operative strategy for fistula-in-ano without division of the anal sphincter. Ann R Coll Surg Engl. 2013;95:461- 467.
  • 5. Vogel JD, Johnson EK, Morris AM, et al. Clinical Practice Guideline for the Management of Anorectal Abscess, Fistula-in-Ano, and Rectovaginal Fistula. Dis Colon Rectum. 2016;59:1117-1133.
  • 6. Ritchie RD, Sackier JM, Hodde JP. Incontinence rates after cutting seton treatment for anal fistula. Colorectal Dis. 2009;11:564-571.
  • 7. Williams JG, Farrands PA, Williams AB, et al. The treatment of anal fistula: ACPGBI position statement. Colorectal Dis. 2007;9:18-50.
  • 8. Williams G, Williams A, Tozer P, et al. The treatment of anal fistula: second ACPGBI Position Statement - 2018. Colorectal Dis. 2018;20:5-31.
  • 9. Medwell SJ, Friend WG. Outpatient anorectal surgery. Dis Colon Rectum. 1979;22:480-482.
  • 10. Shaw D, Ternent CA. Perioperative Management of the Ambulatory Anorectal Surgery Patient. Clin Colon Rectal Surg. 2016;29:7-13.
  • 11. Göttgens KW, Janssen PT, Heemskerk J, et al. Long-term outcome of low perianal fistulas treated by fistulotomy: a multicenter study. Int J Colorectal Dis. 2015;30:213-219.
  • 12. Shawki S, Wexner SD. Idiopathic fistula-in-ano. World J Gastroenterol. 2011;17:3277-3285.
  • 13. Jimenez M, Mandava N. Anorectal Fistula. 2022 Jan 25. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. https://www.ncbi.nlm. nih.gov/books/NBK560657/
  • 14. Zheng L, Shi Y, Zhi C, et al. Loose combined cutting seton for patients with high intersphincteric fistula: a retrospective study. Ann Transl Med. 2020;8:1236.
  • 15. Theerapol A, So BY, Ngoi SS. Routine use of setons for the treatment of anal fistulae. Singapore Med J. 2002;43:305-307.
  • 16. Cariati A. Fistulotomy or seton in anal fistula: a decisional algorithm. Updates Surg. 2013;65:201-205.
  • 17. Gamelas V, Simões G, Santos S, et al. Ambulatory seton placement followed by fistulotomy: efficacy and safety for perianal fistula treatment. Eur J Gastroenterol Hepatol. 2021;33:956-960.
  • 18. Limura E, Giordano P. Modern management of anal fistula. World J Gastroenterol. 2015;21:12-20.
  • 19. Litta F, Parello A, Ferri L, et al. Simple fistula-in-ano: is it all simple? A systematic review. Tech Coloproctol. 2021;25:385-399.

Outcomes of Secondary Fistulotomy Performed After Primary Fistulotomy or Loose Seton According to Operating Room and Outpatient Conditions

Year 2023, Volume: 76 Issue: 3, 278 - 286, 30.06.2024
https://doi.org/10.4274/atfm.galenos.2023.26566

Abstract

Objectives: Perianal fistula has a significant impact on the patient’s quality of life, causing many problems ranging from pain and hygienic problems to sepsis. The primary aim of the present study is to compare the results of primary fistulotomy with fistulotomy following the loose seton technique. The secondary aim is to determine whether these surgical methods are affected by the operating room or polyclinic conditions in terms of disease course and complication rates.

Materials and Methods: A total of 382 patients who underwent surgery were retrospectively analyzed. Uncomplicated low intersphincteric and transsphincteric fistulas are included and high complex fistulas were excluded.

Results: Two hundred and twenty-eight patients underwent only fistulotomy, whereas 154 underwent fistulotomy following the partial healing process after loose seton. The recurrence significantly increases in horseshoes shaped fistulas (p=0.01). In univariate Cox proportional hazard regression analysis, length of fistula tract is proportional with the recurrence rate (p=0.005). In multivariate Cox proportional hazard regression models, transsphincteric fistula is an independent risk factor for recurrence (p=0.006). The recurrence rate was significantly higher in transsphincteric fistulas than in intersphincteric fistulas among patients who underwent fistulotomy (p<0.001). It was determined that neither the type of surgical technique nor the operation performed in the operating room or outpatient clinic conditions made a significant difference in terms of disease course and complication rates (p>0.05).

Conclusion: Transsphincteric fistula is a risk factor for recurrence independent of the surgical technique. However, after a certain period of time following loose seton, secondary fistulotomy into the fistula channel reduces the recurrence rate. In addition, no significant difference was observed in terms of the course of the disease and recurrence after secondary fistulotomy whether it is performed in operating room or outpatient clinic conditions.

Supporting Institution

Sakarya University Faculty of Medicine

References

  • 1. Ramanujam PS, Prasad ML, Abcarian H, Tan AB. Perianal abscesses and fistulas. A study of 1023 patients. Dis Colon Rectum. 1984;27:593-597.
  • 2. Garg P. Comparing existing classifications of fistula-in-ano in 440 operated patients: Is it time for a new classification? A Retrospective Cohort Study. Int J Surg. 2017;42:34-40.
  • 3. Abcarian H. Anorectal infection: abscess-fistula. Clin Colon Rectal Surg. 2011;24:14-21.
  • 4. Fung AK, Card GV, Ross NP, et al. Operative strategy for fistula-in-ano without division of the anal sphincter. Ann R Coll Surg Engl. 2013;95:461- 467.
  • 5. Vogel JD, Johnson EK, Morris AM, et al. Clinical Practice Guideline for the Management of Anorectal Abscess, Fistula-in-Ano, and Rectovaginal Fistula. Dis Colon Rectum. 2016;59:1117-1133.
  • 6. Ritchie RD, Sackier JM, Hodde JP. Incontinence rates after cutting seton treatment for anal fistula. Colorectal Dis. 2009;11:564-571.
  • 7. Williams JG, Farrands PA, Williams AB, et al. The treatment of anal fistula: ACPGBI position statement. Colorectal Dis. 2007;9:18-50.
  • 8. Williams G, Williams A, Tozer P, et al. The treatment of anal fistula: second ACPGBI Position Statement - 2018. Colorectal Dis. 2018;20:5-31.
  • 9. Medwell SJ, Friend WG. Outpatient anorectal surgery. Dis Colon Rectum. 1979;22:480-482.
  • 10. Shaw D, Ternent CA. Perioperative Management of the Ambulatory Anorectal Surgery Patient. Clin Colon Rectal Surg. 2016;29:7-13.
  • 11. Göttgens KW, Janssen PT, Heemskerk J, et al. Long-term outcome of low perianal fistulas treated by fistulotomy: a multicenter study. Int J Colorectal Dis. 2015;30:213-219.
  • 12. Shawki S, Wexner SD. Idiopathic fistula-in-ano. World J Gastroenterol. 2011;17:3277-3285.
  • 13. Jimenez M, Mandava N. Anorectal Fistula. 2022 Jan 25. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. https://www.ncbi.nlm. nih.gov/books/NBK560657/
  • 14. Zheng L, Shi Y, Zhi C, et al. Loose combined cutting seton for patients with high intersphincteric fistula: a retrospective study. Ann Transl Med. 2020;8:1236.
  • 15. Theerapol A, So BY, Ngoi SS. Routine use of setons for the treatment of anal fistulae. Singapore Med J. 2002;43:305-307.
  • 16. Cariati A. Fistulotomy or seton in anal fistula: a decisional algorithm. Updates Surg. 2013;65:201-205.
  • 17. Gamelas V, Simões G, Santos S, et al. Ambulatory seton placement followed by fistulotomy: efficacy and safety for perianal fistula treatment. Eur J Gastroenterol Hepatol. 2021;33:956-960.
  • 18. Limura E, Giordano P. Modern management of anal fistula. World J Gastroenterol. 2015;21:12-20.
  • 19. Litta F, Parello A, Ferri L, et al. Simple fistula-in-ano: is it all simple? A systematic review. Tech Coloproctol. 2021;25:385-399.
There are 19 citations in total.

Details

Primary Language English
Subjects General Surgery, Pathology
Journal Section Research Article
Authors

Hakan Demir

Emre Gönüllü 0000-0001-6391-4414

Merve Yiğit This is me 0000-0001-5217-9629

Gözde Çakırsoy Çakar This is me 0000-0001-6851-0945

Recayi Çapoğlu This is me 0000-0003-4438-4301

Kerem Karaman This is me 0000-0003-0143-9712

Publication Date June 30, 2024
Published in Issue Year 2023 Volume: 76 Issue: 3

Cite

APA Demir, H., Gönüllü, E., Yiğit, M., … Çakırsoy Çakar, G. (2024). Outcomes of Secondary Fistulotomy Performed After Primary Fistulotomy or Loose Seton According to Operating Room and Outpatient Conditions. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 76(3), 278-286. https://doi.org/10.4274/atfm.galenos.2023.26566
AMA Demir H, Gönüllü E, Yiğit M, Çakırsoy Çakar G, Çapoğlu R, Karaman K. Outcomes of Secondary Fistulotomy Performed After Primary Fistulotomy or Loose Seton According to Operating Room and Outpatient Conditions. Ankara Üniversitesi Tıp Fakültesi Mecmuası. June 2024;76(3):278-286. doi:10.4274/atfm.galenos.2023.26566
Chicago Demir, Hakan, Emre Gönüllü, Merve Yiğit, Gözde Çakırsoy Çakar, Recayi Çapoğlu, and Kerem Karaman. “Outcomes of Secondary Fistulotomy Performed After Primary Fistulotomy or Loose Seton According to Operating Room and Outpatient Conditions”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 76, no. 3 (June 2024): 278-86. https://doi.org/10.4274/atfm.galenos.2023.26566.
EndNote Demir H, Gönüllü E, Yiğit M, Çakırsoy Çakar G, Çapoğlu R, Karaman K (June 1, 2024) Outcomes of Secondary Fistulotomy Performed After Primary Fistulotomy or Loose Seton According to Operating Room and Outpatient Conditions. Ankara Üniversitesi Tıp Fakültesi Mecmuası 76 3 278–286.
IEEE H. Demir, E. Gönüllü, M. Yiğit, G. Çakırsoy Çakar, R. Çapoğlu, and K. Karaman, “Outcomes of Secondary Fistulotomy Performed After Primary Fistulotomy or Loose Seton According to Operating Room and Outpatient Conditions”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 76, no. 3, pp. 278–286, 2024, doi: 10.4274/atfm.galenos.2023.26566.
ISNAD Demir, Hakan et al. “Outcomes of Secondary Fistulotomy Performed After Primary Fistulotomy or Loose Seton According to Operating Room and Outpatient Conditions”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 76/3 (June2024), 278-286. https://doi.org/10.4274/atfm.galenos.2023.26566.
JAMA Demir H, Gönüllü E, Yiğit M, Çakırsoy Çakar G, Çapoğlu R, Karaman K. Outcomes of Secondary Fistulotomy Performed After Primary Fistulotomy or Loose Seton According to Operating Room and Outpatient Conditions. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2024;76:278–286.
MLA Demir, Hakan et al. “Outcomes of Secondary Fistulotomy Performed After Primary Fistulotomy or Loose Seton According to Operating Room and Outpatient Conditions”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 76, no. 3, 2024, pp. 278-86, doi:10.4274/atfm.galenos.2023.26566.
Vancouver Demir H, Gönüllü E, Yiğit M, Çakırsoy Çakar G, Çapoğlu R, Karaman K. Outcomes of Secondary Fistulotomy Performed After Primary Fistulotomy or Loose Seton According to Operating Room and Outpatient Conditions. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2024;76(3):278-86.