Özofagus Kanserinde Helicobacter Pylori ve Barret Özofagus’un Rolü = The Role Of Helicobacter Pylori And Barretts Esophagus In Esophageal Cancer

Abstract

Keywords

• -

Özofagus Kanserinde Helicobacter Pylori ve Barret Özofagus’un Rolü

Abstract

Özofagus kanserlerinin gelişiminde; sigara ve alkol kullanımı, beslenme ile ilgili etkenler, genetik ve çevresel faktörler ve bazı predispozan hastalıklar rol almaktadır. Peptik veya kostik özofajit, Barret özofagus, Plummer Winson Sendromu, akalazya, tylosis, gluten enteropatisi gibi hastalıklar predispozan hastalıklardır. Özofagus kanseri oluşumunda Barret özofagusun önemli bir predispozan faktör olduğu tüm otörler tarafından kabul edilmektedir. Helicobacter pylori’nin ise predispozan rol aldığını belirten yayınlar olmakla birlikte bunun tersini iddia eden görüşler de ortaya atılmıştır

Keywords

• Barret Özofagus, Helicobacter Pylori, Özofagus Kanseri

References

1. Ikeda G, İsaji S,Chandra B et al. Prognostic significance of biologic factors in squamo- us cell carcinoma of the esophagus. Cancer 1999 Oct 15;86(8): 1396-405.
2. Yokokawa Y, Ohta S, Hot J et al. Ecological study on the risk of esophageal cancer in Ci- Xian China: the importence of nutritional status and the use of well water. Int J Cancer 1999 Nov 26;83(5):620-4.
3. Ökten İ. Özofagus kanserleri. Güncel Gastro- enteroloji 1999; 3(1): 94-105.
4. Cameron AJ, Souto EO, Smyrk TC. Small adenocarcinomas of the esophagogastric junction: association with intestinal metap- lasia and dysplasia. Am J Gastroenterol 2002 Jun;97(6):1375-80.
5. Grimley CE.Holder RL, Loft DE et al. Heli- cobacter pylori-associated antibodies in pati- ents with duodenal ulcer, gastric and oesop- hageal adenocarcinoma. Eur J Gastroenterol Hepatol 1999 May;11(5):503-9.
6. Quddus MR, Henley JD, Sulaiman RA et al. Helicobacter pylori infection and adenocar- cinoma arising in Barrett’s esophagus. Hum. Pathol. 1997 Sep;28(9):1007-9.
7. Wright TA, Myskow M, Kingsnorth AN. He- licobacter pylori colonization of Barrett’s esophagus and its progression to cancer. Dis. Esophagus 1997 Jul;10(3):196-200.
8. Edelstein ZR, Bronner MP, Rosen SN et al. Risk factors for Barrett’s esophagus among patients with gastroesophageal reflux disease: a community clinic-based case-control study. Am J Gastroenterol 2009 Apr;104(4):834- 42

9. Stein HJ, Siewert JR. Barrett’s esophagus: patho- genesis, epidemiology, functional abnormaliti- es, malignant degeneration, and surgical mana- gement. Dysphagia 1993;8(3):276-88.
10. Blaser MJ. Helicobacter pylori and Rela- ted Organisms. In: Mandell GL, Bennett JE, Dolin RE, eds. Principles and Prac- tice of İnfectious Diseases. 5th ed. New York:Churchill Livingstone; 2000;2285-93.
11. Kuipers EJ, Uyterlinde AM, Pena AS et al. Long-term sequale to Helicobac- ter pylori gastritis. Lancet. 1995 Jun 17; 345(8964):1525-8.
12. Weston AP, Badr AS, Topalovski M et al. Prospective evaluation of the prevalen- ce of gastric Helicobacter pylori infecti- on in patients with GERD, Barrett’s wsop- hagus, Barrett’s dysplasia, and Barrett’s ade- nocarcinoma. Am J Gastroenterol 2000 Feb;95(2):387-94
13. Labenz J, Blum AL, Bayerdörffer E et al. Cu- ring Helicobacter pylori infection in pati- ents with duodenal ulcer may provoke ref- lux esophagitis. Gastroenterology 1997 May;112(5):1442-1447.
14. Werdmuller BF, Loffeld RJ. Helicobacter pylori infection has no role in the pathoge- nesis of reflux esophagitis. Dig Dis Sci 1997 Jan;42(1):103-5.
15. Stein HJ, Siewert JR. Barrett’s esopha- gus: pathogenesis, epidemiology, functio- nal abnormalities, malignant degenerati- on, and surgical management. Dysphagia 1993;8(3):276-88.