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            <front>

                <journal-meta>
                                    <journal-id></journal-id>
            <journal-title-group>
                                                                                    <journal-title>Beykoz Akademi Dergisi</journal-title>
            </journal-title-group>
                                        <issn pub-type="epub">2651-5393</issn>
                                                                                            <publisher>
                    <publisher-name>Beykoz Üniversitesi</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id/>
                                                                                                                                                                                            <title-group>
                                                                                                                        <trans-title-group xml:lang="en">
                                    <trans-title>FOOD ALLERGIES IN CHILDREN</trans-title>
                                </trans-title-group>
                                                                                                                                                                                                <article-title>ÇOCUKLARDA GIDA ALERJİLERİ</article-title>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0001-9381-7295</contrib-id>
                                                                <name>
                                    <surname>Saygı</surname>
                                    <given-names>Birol</given-names>
                                </name>
                                                                    <aff>İSTANBUL TOPKAPI ÜNİVERSİTESİ</aff>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20220501">
                    <day>05</day>
                    <month>01</month>
                    <year>2022</year>
                </pub-date>
                                        <volume>2</volume>
                                        <issue>1</issue>
                                        <fpage>151</fpage>
                                        <lpage>166</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="20211023">
                        <day>10</day>
                        <month>23</month>
                        <year>2021</year>
                    </date>
                                                    <date date-type="accepted" iso-8601-date="20220521">
                        <day>05</day>
                        <month>21</month>
                        <year>2022</year>
                    </date>
                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 2013, Beykoz Akademi Dergisi</copyright-statement>
                    <copyright-year>2013</copyright-year>
                    <copyright-holder>Beykoz Akademi Dergisi</copyright-holder>
                </permissions>
            
                                                                                                <trans-abstract xml:lang="en">
                            <p>We all eat to survive, and most of us enjoy eating. However, recent research shows that one in twenty children under the age of five and one in twenty-five adults is allergic to at least one food. More and more people are becoming aware of food allergies, making it a topic of increasing public concern. Food allergy is becoming a growing concern for parents. Food allergy is a growing public health problem, affecting an estimated 8% of children. A food allergy is defined as an adverse health effect resulting from a specific immune response that occurs reproducibly upon exposure to a particular food. About 40% of children with food allergies have a history of serious reactions that can lead to hospitalization and even death if not treated promptly with appropriate medications. The societal cost of food allergy is large, and it spreads widely to the healthcare system and families. When someone in the family has a food allergy, the whole family is affected. There may be day-to-day concerns about a loved one accidentally eating a food that could cause anaphylaxis, a dangerous allergic reaction. A food allergy is an abnormal response to a food triggered by the body&#039;s immune system. There are a variety of immune responses to food. Sometimes, a reaction to food is not an allergy but another type of reaction called a food intolerance.</p></trans-abstract>
                                                                                                                                    <abstract><p>Hepimiz hayatta kalmak için yeriz ve çoğumuz yemek yemekten zevk alırız. Bununla birlikte, son araştırmalar, beş yaşın altındaki yirmi çocuktan birinin ve yirmi beş yetişkinden ise yine birinin en az bir besine alerjisi olduğunu göstermektedir. Giderek daha fazla insan gıda alerjisinin farkına varmakta ve bu da onu kamuoyunda artan bir endişe konusu haline getirmektedir. Gıda alerjisi, ebeveynler için giderek artan bir endişe haline gelmektedir. Gıda alerjisi, çocukların tahmini %8&#039;ini etkileyen büyüyen bir halk sağlığı sorunudur. Gıda alerjisi, belirli bir gıdaya maruz kalındığında tekrarlanabilir şekilde ortaya çıkan spesifik bir bağışıklık tepkisinden kaynaklanan olumsuz bir sağlık etkisi olarak tanımlanır. Gıda alerjisi olan çocukların yaklaşık %40&#039;ında, uygun ilaçlarla hemen tedavi edilmezse hastaneye yatış ve hatta ölüme yol açabilecek ciddi reaksiyon öyküsü vardır. Besin alerjisinin toplumsal maliyeti büyük olup sağlık sistemi ve ailelere geniş ölçüde yayılmıştır. Ailede bir kişide gıda alerjisi olduğunda tüm aile etkilenir. Sevilen birinin yanlışlıkla anafilaksiye, yani tehlikeli bir alerjik reaksiyona yol açabilecek bir yiyeceği yemesine dair günlük kaygılar olabilir. Gıda alerjisi, vücudun bağışıklık sistemi tarafından tetiklenen bir gıdaya anormal bir tepkidir. Yiyeceklere karşı çeşitli bağışıklık tepkileri vardır. Bazen, gıdaya verilen bir reaksiyon, bir alerji değil, gıda intoleransı olarak adlandırılan başka bir reaksiyon türüdür.</p></abstract>
                                                            
            
                                                                                        <kwd-group>
                                                    <kwd>Gıda Alerjileri</kwd>
                                                    <kwd>  Çocuklarda Gıda Alerjisi</kwd>
                                                    <kwd>  Beslenme</kwd>
                                            </kwd-group>
                            
                                                <kwd-group xml:lang="en">
                                                    <kwd>Food Allergies</kwd>
                                                    <kwd>  Food Allergy in Children</kwd>
                                                    <kwd>  Nutrition</kwd>
                                            </kwd-group>
                                                                                                                                        </article-meta>
    </front>
    <back>
                            <ref-list>
                                    <ref id="ref1">
                        <label>1</label>
                        <mixed-citation publication-type="journal">Anagnostou, K., Fox, A., (2014). Recent advances in the management of food allergy, Clin. Pract., 11(6), 639–647</mixed-citation>
                    </ref>
                                    <ref id="ref2">
                        <label>2</label>
                        <mixed-citation publication-type="journal">Anon, (2017). Türk Gıda Kodeksi Etiketleme ve Tüketicileri Bilgilendirme Yönetmeliği, Resmî Gazete Sayı: 26960</mixed-citation>
                    </ref>
                                    <ref id="ref3">
                        <label>3</label>
                        <mixed-citation publication-type="journal">Anon, (2012). Food Allergy, An Overview, U.S. Department of Health and Human Services, National Institutes of Health, National Institute of Allergy and Infectious Diseases, NIH Publication No. 12-5518, July, 40 s. Anon, (2022a). Wheat Allergy, Mayo Clinic</mixed-citation>
                    </ref>
                                    <ref id="ref4">
                        <label>4</label>
                        <mixed-citation publication-type="journal">https://www.mayoclinic.org/diseases-conditions/wheat-allergy/symptoms-causes/syc-20378897</mixed-citation>
                    </ref>
                                    <ref id="ref5">
                        <label>5</label>
                        <mixed-citation publication-type="journal">Anon, (2022b). Questions and Answers on Monosodium glutamate (MSG),
https://www.fda.gov/food/food-additives-petitions/questions-and-answers-monosodium-glutamate-msg</mixed-citation>
                    </ref>
                                    <ref id="ref6">
                        <label>6</label>
                        <mixed-citation publication-type="journal">Anon, (2022c). CFR - Code of Federal Regulations Title 21, U. S. Food&amp;Drug Administration</mixed-citation>
                    </ref>
                                    <ref id="ref7">
                        <label>7</label>
                        <mixed-citation publication-type="journal">Anon, (2022d). Food Allergen List, https://www.foodallergy.org/about-us</mixed-citation>
                    </ref>
                                    <ref id="ref8">
                        <label>8</label>
                        <mixed-citation publication-type="journal">Baenkler, H. W., (2008). Salicylate Intolerance, Review Article, Dtsch. Arztebl. Int., 105(8): 137–142</mixed-citation>
                    </ref>
                                    <ref id="ref9">
                        <label>9</label>
                        <mixed-citation publication-type="journal">Bayır, A. G., Can, B., Ekingen, Ş., (2021). Food Allergy in Children, Bezmialem Science, 9(3):373-379</mixed-citation>
                    </ref>
                                    <ref id="ref10">
                        <label>10</label>
                        <mixed-citation publication-type="journal">Bettcher, C. M., Rockwell P. G. ve Ravikumar, R., (2020). Managing food allergy in children: An evidence-based update, The Journal of Family Practice, 69(7):336-343</mixed-citation>
                    </ref>
                                    <ref id="ref11">
                        <label>11</label>
                        <mixed-citation publication-type="journal">Bingöl, A., (2021). Çocuklarda Besin Alerjileri Araştırması, Akdeniz Üniversitesi, Tıp Fakültesi, 85 s.</mixed-citation>
                    </ref>
                                    <ref id="ref12">
                        <label>12</label>
                        <mixed-citation publication-type="journal">Bold, J., (2012). Considerations for the diagnosis and management of sulphite sensitivity, Gastroenterol Hepatol Bed Bench., 5(1): 3–6</mixed-citation>
                    </ref>
                                    <ref id="ref13">
                        <label>13</label>
                        <mixed-citation publication-type="journal">Boye, J. I., Danquah, A. O., Thang, C. L., Zhao, X. (2012). Food Allergens, Chapter 42, in “Food Biochemistry and Food Processing”, Second Edition. Edited by Benjamin K. Simpson, Leo M.L. Nollet, Fidel Toldra, Soottawat Benjakul, Gopinadhan Paliyath ve Y.H. Hui., John Wiley &amp; Sons Inc., s. 798-819</mixed-citation>
                    </ref>
                                    <ref id="ref14">
                        <label>14</label>
                        <mixed-citation publication-type="journal">Can, C., Altınel, N., Bülbül, L., Civan, H. A., Hatipoğlu, S., (2019). Besin Alerjili Olguların Klinik ve Laboratuvar Özellikleri: Tek Merkez Deneyimi, Med. Bull. Sisli Etfal Hosp., 53(3):296–299</mixed-citation>
                    </ref>
                                    <ref id="ref15">
                        <label>15</label>
                        <mixed-citation publication-type="journal">Caubet, J. C. ve Wang, J., (2011). Current understanding of egg allergy, Pediatr. Clin. North Am., 58(2): 427–443</mixed-citation>
                    </ref>
                                    <ref id="ref16">
                        <label>16</label>
                        <mixed-citation publication-type="journal">Chin, B., Chan, E. S., Goldman, R. D., (2014). Early exposure to food and food allergy in children, Canadian Family Physician, 60, 338-339</mixed-citation>
                    </ref>
                                    <ref id="ref17">
                        <label>17</label>
                        <mixed-citation publication-type="journal">Devdas, J. M., Mckie, C., Fox, A. T., Ratageri, V. H., (2017). Food Allergy in Children: An Overview, Review Article, Indian J. Pediatr., 7 s.</mixed-citation>
                    </ref>
                                    <ref id="ref18">
                        <label>18</label>
                        <mixed-citation publication-type="journal">Denham, J. M., Hill, I. D., (2013). Celiac Disease and Autoimmunity: Review and Controversies, Curr. Allergy Asthma Rep., 13(4), 347–353</mixed-citation>
                    </ref>
                                    <ref id="ref19">
                        <label>19</label>
                        <mixed-citation publication-type="journal">Duthie, G. G., Wood, A. D., (2011). Natural salicylates: foods, functions, and disease prevention, Journal of Food Function, 2(9):515-520</mixed-citation>
                    </ref>
                                    <ref id="ref20">
                        <label>20</label>
                        <mixed-citation publication-type="journal">Ebert, K. ve Witt, H., (2016). Fructose malabsorption, Molecular and Cellular Pediatrics, 3, (10), 5.</mixed-citation>
                    </ref>
                                    <ref id="ref21">
                        <label>21</label>
                        <mixed-citation publication-type="journal">Eren, S., (2020). Food-Related Barriers to Gastronomy and Tourism: The Role of Food Allergies and Diet Preferences, MANAS Sosyal Araştırmalar Dergisi, 9(2), 1117-1129</mixed-citation>
                    </ref>
                                    <ref id="ref22">
                        <label>22</label>
                        <mixed-citation publication-type="journal">Fedewa, A. ve Rao, S. S. C., (2014). Dietary fructose intolerance, fructan intolerance and FODMAPs, Curr. Gastroenterol Rep., 16(1), 370-378</mixed-citation>
                    </ref>
                                    <ref id="ref23">
                        <label>23</label>
                        <mixed-citation publication-type="journal">Jutel, M., Blaser, K., Akdis, C. A., (2006). The role of histamine in regulation of immune responses, Chem. Immunol Allergy, 91,174-187</mixed-citation>
                    </ref>
                                    <ref id="ref24">
                        <label>24</label>
                        <mixed-citation publication-type="journal">Gibson, P. R. ve Shepherd, S. J., (2010). Evidence-based dietary management of functional gastrointestinal symptoms: The FODMAP approach, Journal of Gastroenterology and Hepatology, 25(2), 252-258</mixed-citation>
                    </ref>
                                    <ref id="ref25">
                        <label>25</label>
                        <mixed-citation publication-type="journal">Gönül, B., (2011). Bursa İli 6-14 Yaş Grubu Çocuklarda Besin Alerjisi ve Semptomlarının Sıklığı, T.C. Uludağ Üniversitesi, Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Uzmanlık Tezi, 89.</mixed-citation>
                    </ref>
                                    <ref id="ref26">
                        <label>26</label>
                        <mixed-citation publication-type="journal">Gupta, R. S., Dyer, A. A., Jain, N., Greenhawt, M. J., (2013). Childhood Food Allergies: Current Diagnosis, Treatment, and Management Strategies, Mayo Foundation for Medical Education and Research in Mayo Clin Proc., 88(5), 512-526.</mixed-citation>
                    </ref>
                                    <ref id="ref27">
                        <label>27</label>
                        <mixed-citation publication-type="journal">Kobylewski, S. ve Jacobson, M. F., (2012). Toxicology of food dyes, Int. J. Occup. Environ. Health, 18(3), 220-246.</mixed-citation>
                    </ref>
                                    <ref id="ref28">
                        <label>28</label>
                        <mixed-citation publication-type="journal">Kovacova-Hanuskova, E., 1, T Buday, T, Gavliakova, S., Plevkova, J., (2015). Histamine, histamine intoxication and intolerance, Allergol Immunopathol (Madr), 43(5), 498-506.</mixed-citation>
                    </ref>
                                    <ref id="ref29">
                        <label>29</label>
                        <mixed-citation publication-type="journal">Landolt, H., P., 2012: “No Thanks, Coffee Keeps Me Awake”: Individual Caffeine Sensitivity Depends on ADORA2A Genotype, Sleep Research Society, 35(7), 899–900.</mixed-citation>
                    </ref>
                                    <ref id="ref30">
                        <label>30</label>
                        <mixed-citation publication-type="journal">Lindseth, G. N., Coolahan, S. E., Petros, T. V., Lindseth, P. D., (2014). Neurobehavioral effects of aspartame consumption, Research Nurs. Health, 37(3), 185-193.</mixed-citation>
                    </ref>
                                    <ref id="ref31">
                        <label>31</label>
                        <mixed-citation publication-type="journal">Lyons, S. A., Clausen, M., Knulst, A. C., Ballmer-Weber, B. K., Fernandez-Rivas, M., Barreales, L., Bieli, C., Dubakiene, R., Fernandez-Perez, C., Jedrzejczak-Czechowicz, M., Kowalski, M. L., Kralimarkova, T., Kummeling, I., Mustakov, T. B., Papadopoulos, N. G., Popov, T. A., Xepapadaki, P., Welsing, P. M. J., Potts, J., Mills, C., van Ree, R., Burney, P. G. J., Le, T., (2020). Prevalence of Food Sensitization and Food Allergy in Children Across Europe, J. Allergy Clin. Immunol. Pract., 8(8), 2737-2797</mixed-citation>
                    </ref>
                                    <ref id="ref32">
                        <label>32</label>
                        <mixed-citation publication-type="journal">Magee, F., Byrne, A., Hourihane, J., McGinley, A. M., (2020). Food Allergy in Children, Quick Reference Guide, Quality and Safety in Practice Committee, 48.</mixed-citation>
                    </ref>
                                    <ref id="ref33">
                        <label>33</label>
                        <mixed-citation publication-type="journal">Maintz, L., Novak, N., (2007). Histamine and histamine intolerance, Am. J. Clin. Nutr., 85(5), 1185-1196.</mixed-citation>
                    </ref>
                                    <ref id="ref34">
                        <label>34</label>
                        <mixed-citation publication-type="journal">Mattar, R., Ferraz de Campos Mazo, F., Carrilho, F. J., (2012). Lactose intolerance: diagnosis, genetic, and clinical factors, Clin. Exp. Gastroenterol., 5, 113–121</mixed-citation>
                    </ref>
                                    <ref id="ref35">
                        <label>35</label>
                        <mixed-citation publication-type="journal">McAdams, B., Deng, A., MacLaurin, T., (2018). Food allergy knowledge, attitudes, and resources of restaurant employees, British Food Journal, 120(11), 2681-2694.</mixed-citation>
                    </ref>
                                    <ref id="ref36">
                        <label>36</label>
                        <mixed-citation publication-type="journal">Molina-Infante, J., Santolaria, S., Sanders, D. S., Fernández-Bañares, F., (2015). Systematic review: noncoeliac gluten sensitivity, Aliment Pharmacol Ther., 41(9), 807-820.</mixed-citation>
                    </ref>
                                    <ref id="ref37">
                        <label>37</label>
                        <mixed-citation publication-type="journal">Nanayakkara, W. S., Skidmore, P. M. L., O’Brien, L., Wilkinson, T. J. ve Gearry, R. B., (2016). Efficacy of the low FODMAP diet for treating irritable bowel syndrome: the evidence to date, Clin. Exp. Gastroenterol., 9, 131–142.</mixed-citation>
                    </ref>
                                    <ref id="ref38">
                        <label>38</label>
                        <mixed-citation publication-type="journal">Nigg, J. T., Holton, K., (2014). Restriction and Elimination Diets in ADHD TreatmentChild Adolesc Psychiatr Clin N Am. 2014 Oct; 23(4), 937–953.</mixed-citation>
                    </ref>
                                    <ref id="ref39">
                        <label>39</label>
                        <mixed-citation publication-type="journal">Oku, T. ve Nakamura, S., (2007). Threshold for transitory diarrhea induced by ingestion of xylitol and lactitol in young male and female adults, J. Nutr. Sci. Vitaminol, 53(1), 13-20.</mixed-citation>
                    </ref>
                                    <ref id="ref40">
                        <label>40</label>
                        <mixed-citation publication-type="journal">Peters, R. L., Krawiec, M., Koplin, J. J., Santos, A. F., (2020). Update on food allergy, Pediatr. Allergy Immunol., 32, 647–657.</mixed-citation>
                    </ref>
                                    <ref id="ref41">
                        <label>41</label>
                        <mixed-citation publication-type="journal">Pratten, J., Towers, N., (2004). Food allergies and the UK catering industry, A study of the training needs for the industry to serve those with food allergies, Journal of European Industrial Training, 28(6), 490-498.</mixed-citation>
                    </ref>
                                    <ref id="ref42">
                        <label>42</label>
                        <mixed-citation publication-type="journal">Radke, T., Brown, L. G., Hoover, E. R., Faw, B. V., Reimann, D., Wong, M. R., Nicholas, D., Barkley, J., Ripley, D., (2016). Food Allergy Knowledge and Attitudes of Restaurant Managers and Staff: An EHS-Net Study, Journal of Food Protection, 79(9), 1588–1598.</mixed-citation>
                    </ref>
                                    <ref id="ref43">
                        <label>43</label>
                        <mixed-citation publication-type="journal">Rizkalla, S. W., (2010). Health implications of fructose consumption: A review of recent data, Nutr. Metab., 7, 8294.</mixed-citation>
                    </ref>
                                    <ref id="ref44">
                        <label>44</label>
                        <mixed-citation publication-type="journal">Silva, S., Geromi, M., Halken, S., Host, A., Panesar, S. S., Muraro, A., Werfel, T., Hoffmann-Sommergruber, K., Roberts, G., Cardona, V., Dubois, A. E. J., Poulsen, L. K., Van Ree, R., Vlieg-Boerstra, B., Agache, I., Grimshaw, K., O’Mahony, L., Venter, c., Arshad, S. H., Sheikh, A., (2013). Primary prevention of food allergy in children and adults: systematic review, Allergy, 69, 581–589.</mixed-citation>
                    </ref>
                                    <ref id="ref45">
                        <label>45</label>
                        <mixed-citation publication-type="journal">Salsabila, H. Y., Putera, A. M., Baskoro, A., (2021). Correlation between nutritional status and children’s activity with food allergy: A cross-sectional study, Annals of Medicine and Surgery, 68, 4.</mixed-citation>
                    </ref>
                                    <ref id="ref46">
                        <label>46</label>
                        <mixed-citation publication-type="journal">Scurlock, A. M., Lee, L. A., Burks, W., (2005). Food Allergy in Children, Immunol Allergy Clin. North America, 25, 369– 388.</mixed-citation>
                    </ref>
                                    <ref id="ref47">
                        <label>47</label>
                        <mixed-citation publication-type="journal">Şenol, H. D., Köksal, B. T., (2015). Van’ da Besin Alerjik Çocukların Klinik Özellikleri, Van Tıp Dergisi, 22(4), 266-272.</mixed-citation>
                    </ref>
                                    <ref id="ref48">
                        <label>48</label>
                        <mixed-citation publication-type="journal">Tang, M., Allen, K., (2017). Managing Kids’ Food Allergies, Allergy &amp; Anaphylaxis Australia, Special Edition, John Wiley &amp; Sons Australia, ISBN: 978-0-730-34512-1, 69.</mixed-citation>
                    </ref>
                                    <ref id="ref49">
                        <label>49</label>
                        <mixed-citation publication-type="journal">Tercanlı, E., Atasever, M., (2021). Besin Alerjileri, Academic Platform Journal of Halal Lifestyle, 3(1), 31-53.</mixed-citation>
                    </ref>
                                    <ref id="ref50">
                        <label>50</label>
                        <mixed-citation publication-type="journal">Vally, H. ve Misso, N. L. A., (2012). Adverse reactions to the sulphite additives, Gastroenterol Hepatol Bed Bench., Winter, 5(1), 16–23.</mixed-citation>
                    </ref>
                                    <ref id="ref51">
                        <label>51</label>
                        <mixed-citation publication-type="journal">Yang, A., Palmer, A. A., de Wit, H., (2014). Genetics of caffeine consumption and responses to caffeine, Psychopharmacology (Berl), 211(3), 245–257.</mixed-citation>
                    </ref>
                                    <ref id="ref52">
                        <label>52</label>
                        <mixed-citation publication-type="journal">Zopf, Y., Hahn, E. G., Raithel, M., Baenkler, H. W., Silbermann, A., (2009). The Differential Diagnosis of Food Intolerance, Dtsch. Arztebl. Int., 106(21), 359–370.</mixed-citation>
                    </ref>
                            </ref-list>
                    </back>
    </article>
