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Investigation of the genetic defect of Cholesterol deficiency and Brachyspina syndrome in Holstein breed cattle breed in Eskisehir

Yıl 2024, , 7 - 10, 30.06.2024
https://doi.org/10.51539/biotech.1408472

Öz

As a result of the intensive use of biotechnology in cattle breeding, the incidence of rare genetic defects in the population has started to increase. Studies have focused on identifying cattle with genetic defects using molecular methods. Identifying carrier cattle is crucial to reducing genetic defects in future generations. In a previous study conducted in Turkiye, Brachyspina Syndrome (BS) and Cholesterol Deficiency (CD) were detected in Holstein cattle. With regard to these two genetic defects, in the study conducted to investigate samples were taken from the Holstein cattle reared in Eskişehir by using PCR technique. 2 and 11 cattle were found to be carriers of the BS and CD, respectively, among 112 Holstein cattle. The possibility of the spread of genetic defects and economic damage can be prevented using molecular techniques. Some molecular methods can be used to detect genetic diseases. In this way, herds free of genetic defects can be produced.

Etik Beyan

The procedures involving sample collection were approved by Eskisehir Osmangazi University Medical and Surgical Experimental Research Center Committee (TICAM) Decision 2011/242.

Kaynakça

  • Agerholm JS (2007) Inherited disorders in Danish cattle, APMIS 115:1-76
  • Agerholm JS, McEvoy F, Arnbjerg J (2006) Brachyspina syndrome in a Holstein calf. J Vet Diagn Invest 18:418-422
  • Agerholm JS, Peperkamp K (2007) Familial occurrence of Danish and Dutch cases of the bovine brachyspina syndrome. BMC Vet Res 3:8
  • Agerholm JS, DeLay J, Hicks B, Fredholm M (2010) First confirmed case of the bovine brachyspina syndrome in Canada. Can Vet J 51:1349-1350
  • Bedir Dibıc K (2021) Türkiye’de Yetiştirilen Yerli Sığır ve Siyah Alaca Sığır Irklarında Brachyspina Sendromu ve Kolesterol Eksikliği Genetik Kusurlarının Belirlenmesi. Akdeniz Üniversitesi Fen Bilimleri Ensitüsü Tarımsal Biyoteknoloji Antalya
  • Buck BC, Ulrich R, Wöhlke A, Kuiper H, Baumgärtner W. (2010) Vertebral and multiple organ malformations in a black and white German Holstein calf. Berliner Und Münchener Tierärztliche Wochenschrift 123:251-255
  • Charlier C, Agerholm JS, Coppieters W., et al. (2012) A deletion in bovine FANCI gene compromises fertility by causing fetal death and brachyspine, PLoS ONE 7(8)
  • Chao CH, Chen YM, Lee KH (2020) Genotype screening of bovine brachyspina in Taiwan Holstein cows. Am J Anim Vet Sci 15(3):206-210
  • Kaminski S, Rusc A (2016) Cholesterol deficiency-new genetic defect transtmitted to Polish Holstein-Fresian cattle. Pol J Vet Sci 19(4):885-887
  • Kipp S, Segelke D, Reinhardt F, Reents R, Schierenbeck S, Wurmser C, Pausch H, Fries R, Thaller G, Tetens J, Pott J (2015) A new Holstein haplotype affecting calf survival. Interbull Bulletin p.49
  • Li Y, Zhai L, Fang L, Zhang S, Liu L, Zhu Y, Xue J, Xiaoqing L, Qiao L, Sun D (2016) A novel multiplex polymerase chain reaction method for the identification of brachyspina syndrome carriers in Chinese Holstein cattle. J Vet Sci Med Diagn 5(3)
  • Meydan H, Bedir Dibıc K, Vural O, Yıldız, M.A, Agerholm J (2023) Prevalence of carriers of cholesterol deficiency-associated APOB mutation in some native, Holstein and Simmental cattle breeds in Turkiye. Turk J Vet Anim Sci 47(6):584-587
  • Menzi F, Besuchet‐Schmutz N, Fragnière M, Hofstetter S, Jagannathan V, Mock T, Raemy A, Studer E, Mehinagic K, Regenscheit N, Meylan M (2016) A transposable element insertion in ABOP causes cholesterol deficiency in Holstein cattle. Anim Genet 47(2):253-257
  • OMIA (2023) https://www.omia.org/OMIA001965/9913/ Accessed: 02/05/2023
  • Rusc A, Kaminski S (2015) Detection of brachyspina carriers within Polish Holstein-Fresian bulls. Pol J Vet Sci 18(2):453-454
  • Schütz E, Wehrhahn C, Wanjek M, Bortfeld R, Wemheuer WE, Beck J, Brenig B (2016) The Holstein Friesian lethal haplotype 5 (HH5) results from a complete deletion of TBF1M and cholesterol deficiency (CDH) from an ERV-(LTR) insertion into the coding region of APOB. PLoS ONE 11(4) :e0154602.
  • Testoni S, Diana A, Olzi E, Gentile A (2008) Brachyspina syndrome in two Holstein calves. Vet J 177(1):144-146
Yıl 2024, , 7 - 10, 30.06.2024
https://doi.org/10.51539/biotech.1408472

Öz

Kaynakça

  • Agerholm JS (2007) Inherited disorders in Danish cattle, APMIS 115:1-76
  • Agerholm JS, McEvoy F, Arnbjerg J (2006) Brachyspina syndrome in a Holstein calf. J Vet Diagn Invest 18:418-422
  • Agerholm JS, Peperkamp K (2007) Familial occurrence of Danish and Dutch cases of the bovine brachyspina syndrome. BMC Vet Res 3:8
  • Agerholm JS, DeLay J, Hicks B, Fredholm M (2010) First confirmed case of the bovine brachyspina syndrome in Canada. Can Vet J 51:1349-1350
  • Bedir Dibıc K (2021) Türkiye’de Yetiştirilen Yerli Sığır ve Siyah Alaca Sığır Irklarında Brachyspina Sendromu ve Kolesterol Eksikliği Genetik Kusurlarının Belirlenmesi. Akdeniz Üniversitesi Fen Bilimleri Ensitüsü Tarımsal Biyoteknoloji Antalya
  • Buck BC, Ulrich R, Wöhlke A, Kuiper H, Baumgärtner W. (2010) Vertebral and multiple organ malformations in a black and white German Holstein calf. Berliner Und Münchener Tierärztliche Wochenschrift 123:251-255
  • Charlier C, Agerholm JS, Coppieters W., et al. (2012) A deletion in bovine FANCI gene compromises fertility by causing fetal death and brachyspine, PLoS ONE 7(8)
  • Chao CH, Chen YM, Lee KH (2020) Genotype screening of bovine brachyspina in Taiwan Holstein cows. Am J Anim Vet Sci 15(3):206-210
  • Kaminski S, Rusc A (2016) Cholesterol deficiency-new genetic defect transtmitted to Polish Holstein-Fresian cattle. Pol J Vet Sci 19(4):885-887
  • Kipp S, Segelke D, Reinhardt F, Reents R, Schierenbeck S, Wurmser C, Pausch H, Fries R, Thaller G, Tetens J, Pott J (2015) A new Holstein haplotype affecting calf survival. Interbull Bulletin p.49
  • Li Y, Zhai L, Fang L, Zhang S, Liu L, Zhu Y, Xue J, Xiaoqing L, Qiao L, Sun D (2016) A novel multiplex polymerase chain reaction method for the identification of brachyspina syndrome carriers in Chinese Holstein cattle. J Vet Sci Med Diagn 5(3)
  • Meydan H, Bedir Dibıc K, Vural O, Yıldız, M.A, Agerholm J (2023) Prevalence of carriers of cholesterol deficiency-associated APOB mutation in some native, Holstein and Simmental cattle breeds in Turkiye. Turk J Vet Anim Sci 47(6):584-587
  • Menzi F, Besuchet‐Schmutz N, Fragnière M, Hofstetter S, Jagannathan V, Mock T, Raemy A, Studer E, Mehinagic K, Regenscheit N, Meylan M (2016) A transposable element insertion in ABOP causes cholesterol deficiency in Holstein cattle. Anim Genet 47(2):253-257
  • OMIA (2023) https://www.omia.org/OMIA001965/9913/ Accessed: 02/05/2023
  • Rusc A, Kaminski S (2015) Detection of brachyspina carriers within Polish Holstein-Fresian bulls. Pol J Vet Sci 18(2):453-454
  • Schütz E, Wehrhahn C, Wanjek M, Bortfeld R, Wemheuer WE, Beck J, Brenig B (2016) The Holstein Friesian lethal haplotype 5 (HH5) results from a complete deletion of TBF1M and cholesterol deficiency (CDH) from an ERV-(LTR) insertion into the coding region of APOB. PLoS ONE 11(4) :e0154602.
  • Testoni S, Diana A, Olzi E, Gentile A (2008) Brachyspina syndrome in two Holstein calves. Vet J 177(1):144-146
Toplam 17 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Tarımda Hayvan Biyoteknolojisi
Bölüm Research Articles
Yazarlar

Beste Göneci 0000-0002-7183-0170

Muhammet Kaya 0000-0001-6474-121X

Yayımlanma Tarihi 30 Haziran 2024
Gönderilme Tarihi 22 Aralık 2023
Kabul Tarihi 4 Mart 2024
Yayımlandığı Sayı Yıl 2024

Kaynak Göster

APA Göneci, B., & Kaya, M. (2024). Investigation of the genetic defect of Cholesterol deficiency and Brachyspina syndrome in Holstein breed cattle breed in Eskisehir. Bulletin of Biotechnology, 5(1), 7-10. https://doi.org/10.51539/biotech.1408472
AMA Göneci B, Kaya M. Investigation of the genetic defect of Cholesterol deficiency and Brachyspina syndrome in Holstein breed cattle breed in Eskisehir. Bull. Biotechnol. Haziran 2024;5(1):7-10. doi:10.51539/biotech.1408472
Chicago Göneci, Beste, ve Muhammet Kaya. “Investigation of the Genetic Defect of Cholesterol Deficiency and Brachyspina Syndrome in Holstein Breed Cattle Breed in Eskisehir”. Bulletin of Biotechnology 5, sy. 1 (Haziran 2024): 7-10. https://doi.org/10.51539/biotech.1408472.
EndNote Göneci B, Kaya M (01 Haziran 2024) Investigation of the genetic defect of Cholesterol deficiency and Brachyspina syndrome in Holstein breed cattle breed in Eskisehir. Bulletin of Biotechnology 5 1 7–10.
IEEE B. Göneci ve M. Kaya, “Investigation of the genetic defect of Cholesterol deficiency and Brachyspina syndrome in Holstein breed cattle breed in Eskisehir”, Bull. Biotechnol., c. 5, sy. 1, ss. 7–10, 2024, doi: 10.51539/biotech.1408472.
ISNAD Göneci, Beste - Kaya, Muhammet. “Investigation of the Genetic Defect of Cholesterol Deficiency and Brachyspina Syndrome in Holstein Breed Cattle Breed in Eskisehir”. Bulletin of Biotechnology 5/1 (Haziran 2024), 7-10. https://doi.org/10.51539/biotech.1408472.
JAMA Göneci B, Kaya M. Investigation of the genetic defect of Cholesterol deficiency and Brachyspina syndrome in Holstein breed cattle breed in Eskisehir. Bull. Biotechnol. 2024;5:7–10.
MLA Göneci, Beste ve Muhammet Kaya. “Investigation of the Genetic Defect of Cholesterol Deficiency and Brachyspina Syndrome in Holstein Breed Cattle Breed in Eskisehir”. Bulletin of Biotechnology, c. 5, sy. 1, 2024, ss. 7-10, doi:10.51539/biotech.1408472.
Vancouver Göneci B, Kaya M. Investigation of the genetic defect of Cholesterol deficiency and Brachyspina syndrome in Holstein breed cattle breed in Eskisehir. Bull. Biotechnol. 2024;5(1):7-10.