Cilt: 3 Sayı: 2, 30.12.2022

Yıl: 2022

The Bulletin of Biotechnology is an International, Peer-reviewed, and Open-access journal and provides a medium for the publication of both full-length articles and short communications on novel and innovative aspects of biotechnology. The Journal will accept papers ranging from genetic or molecular biological positions to those covering biochemical, chemical or bioprocess engineering aspects as well as computer application of new software concepts provided that in each case, the material is directly relevant to biotechnological systems.

The journal covers all the broad topics in Biotechnology including 

  • in any field of Biotechnology, Biochemistry, Microbiology and Industrial Microbiology, Agricultural Biotechnology.

  • in any field related to Food Biotechnology, Genetic Engineering and Commercial Biotechnology.

  • in any field of Biotechnology related to Drugs and Pharmaceutical products for human beings, animals and plants.

  • in any field related to Environmental Biotechnology, Waste Treatment of Liquids, Solids and Gases; Sustainability.

  • in any field related to Biotechnological Engineering, Industrial Biotechnology and Instrumentation.

  • in any field related to Nano-technology.

  • in any field related to Plant Biotechnology.


  • The manuscript should be prepared according to the given template. Please download the Manuscript_Template and upload your edited manuscript according to this template.

Click for the Manuscript Template

  • All authors on a submitted paper must sign the copyright release form and it should be uploaded as PDF or JPEG.
Click here for Copyright Release Form

Author fees / Access: The Journal does NOT charge a fee for submission, processing or publication from authors. The Journal database is fully open access and full text of published articles are available for everyone who can get access to the Journal website free of cost. 

Plagiarism : The similarity level of the manuscript to be submitted to the journal (excluding references) should be below 20%. Validity similarity control programs are Ithenticate and Turnitin.

Articles are full-length research reports that contain detailed descriptions of experimental work, with clear interpretation and discussion of the theoretical and experimental results and data. Articles should be structured under the section headings Introduction, Materials and Methods, Results, Discussion, Acknowledgment, Nomenclature/Appendix (if applicable), and References. Authors should present their material with utmost clarity and conciseness and in a logical manner. Constant repetition of experimental procedures, information, and facts among sections should be avoided. 

 The organization shown below should be followed (in the order was given):


Articles must include an Abstract of 250 words or fewer. The Abstract should not repeat information already present in the title. It should be suitable for direct inclusion in Current Contents, Chemical Abstracts, and Biological Abstracts, etc.


Immediately after the abstract, provide a maximum of 6 keywords. Please avoid general terms, multiple concepts (avoid, for example, "and" "of"), and abbreviations. Only abbreviations firmly established in the field may be eligible.



The Introduction presents the purpose of the studies reported and their relationship to earlier work in the field. It should not be an extensive review of the literature. Use only those references required to provide the most salient background to allow the readers to understand and evaluate the purpose and results of the present study without referring to previous publications on the topic.


Materials and Methods

The Materials and Methods section should be brief but include sufficient technical information to allow the experiments to be repeated by a qualified reader. Only new methods should be described in detail. Cite previously published procedures in References.



The Results section should include the rationale or design of the experiments as well as the results of the experiments. Results can be presented in figures, tables, and text. Reserve extensive discussion of the results for the Discussion section.


Discussion  / Results and Discussion

The Discussion section should focus on the interpretation of the results rather than a repetition of the Results section. The Results and Discussion sections may be combined into one section when substantial redundancy cannot be avoided in two separate sections or if a long discussion is not warranted.



Place Acknowledgments, including information on the source of any financial support received for the work being published, before the References.

Citation in text

All citations in the text should refer to:

Single author: the author's name (without initials, unless there is ambiguity) and the year of publication (Dogan 2019); Two authors: both authors' names and the year of publication (Dogan and Cicek 2017); Three or more authors: first author's name followed by 'et al.' and the year of publication (Dogan et al. 2015).

Citations may be made directly (or parenthetically). Groups of references should be listed first alphabetically, then chronologically. Examples: 'as demonstrated (Allan 2000a, 2000b; Allan and Jones 1999).  Kramer et al. (2010) have recently shown ....'


References should be arranged first alphabetically and then further sorted chronologically if necessary. More than one reference from the same author(s) in the same year must be identified by the letters 'a', 'b', 'c', etc., placed after the year of publication. ………. ., ……… 2018. ……. ….. ……….. …. (Times 9 pt, single spaced, paragraph justified, 1 cm hanging indent, 4 pt

Journal article

Fajardo AJ (2009) A global view of antibiotic resistance. Bull Biotech 34:44-65
Martinez JL, Garmendia L (2009) A global view of antibiotic resistance. Bull Biotech 34:44-65
Martinez JL, Fajardo A, Garmendia L, Hernandez A, Linares JF, Martinez-Solano L, Sanchez MB (2009) A global view of antibiotic resistance. Bull Biotech 34:44-65

Inclusion of issue number (optional)
Saunders DS (1976) The biological clock of insects. Sci Am 234(2):114-121

Journal article with DOI (and with page numbers)
Slifka MK, Whitton JL (2000) Clinical implications of dysregulated cytokine production. J Mol Med 78:74-80. doi:10.1007/s001090000086

Book chapter
Brown B, Aaron M (2001) The politics of nature. In: Smith J (ed) The rise of modern genomics, 3rd edn. Wiley, New York

Book, authored
South J, Blass B (2001) The future of modern genomics. Blackwell, London

Chapter in a book in a series
Smith SE (1976) Neuromuscular blocking drugs in man. In: Zaimis E (ed) Neuromuscular junction. Handbook of experimental pharmacology, vol 42. Springer, Heidelberg, pp 593-660

Proceedings without an editor (without a publisher)
Chung S-T, Morris RL (1978) Isolation and characterization of plasmid deoxyribonucleic acid from Streptomyces fradiae. In: Abstracts of the 3rd international symposium on the genetics of industrial microorganisms, University of Wisconsin, Madison, 4-9 June 1978

Patent. Name and date of the patent are optional
Norman LO (1998) Lightning rods. US Patent 4,379,752, 9 Sept 1998

Online document
Doe J (2019) Title of subordinate document. In: The dictionary of substances and their effects. Royal Society of Chemistry. Available via DIALOG. of subordinate document. Accessed 21 Sept 2019

Online database
Healthwise Knowledgebase (2019) US Pharmacopeia, Rockville. Accessed 21 Sept 2019


Tables should be typewritten separately from the main text and in an appropriate font size to preferably fit each table on a separate page. Each table must be numbered with Arabic numerals (e.g., Table 1, Table 2) and include a title. Place footnotes to tables below the table body and indicate them with superscript lowercase letters (a, b, c, etc), not symbols. Do not use vertical rulings in the tables. Each column in a table must have a heading, and abbreviations, when necessary, should be defined in the footnotes. 


Figures should be provided separately from the main text. Use Arabic numerals to number all figures (e.g., Fig 1, Fig 2) according to their sequence in the text. The figure number must appear well outside the boundaries of the image itself. Multipart figures should be numbered in uppercase and bold font letters (a, b, c, etc) without parenthesis, both on the figure itself and in the figure legends.


All abbreviations should be defined at their first use in the text only; do not repeat the definition of abbreviations thereafter.

Note that the Bulletin of Biotechnology uses the following specific design styles (Nomenclature, abbreviations, units and symbols):



The Bulletin of Biotechnology prefers American spelling (e.g., labelling, sulfur, nonspecific, antiviral), abbreviations (Table 1), and nomenclature to follow internationally agreed recommendations. However, authors may use commonly used abbreviations/acronyms but these must be defined in the text at first citation and included in the Abbreviations list.


It is often convenient, especially in figures and table headings, to give a multiple of the quantity set or measured by multiplying it by a stated factor. The units in which it is expressed should not be multiplied by a number but may be indicated by prefixes such as M, k, m, μ, n or p (see Table 2).


The Bulletin of Biotechnology prefers the IUBMB recommendations on symbolism and terminology in rate/equilibrium constants and enzyme kinetics. e.g., KmKsk1kcatVmaxV0, E0, EhMr, I0, ΔGa (i.e., subscripted, non-italicized).


SI (Systeme International d' Unites) units and quantities should be used (see Tables below) but Å, cal, p.p.m. can be used where appropriate.


Leave a space between a number and it's unit of measure. (Exception, do not leave a space between a number and the temperature degree, per cent, angular degree, angular minute, or angular second symbols, 15°C, 50%, 90°, 75', 18" ).


Use a slash (/) in units of measure (i.e., g/ml rather than g ml-1).


Use a slash (/) in spelt-out units of measure, not the word "per", before the abbreviation for a unit in complex expressions. e.g., 50 μg of peptide/ml, 25 mg of drug/kg of body weight, 10 counts/s, 12 domains/cm3, 2 × 103 ions/min, 0.8 keV/channel, and 125 conversions/mm2.


Do not add an "s" to make the plural of any abbreviated units of measure. e.g., 50 mg (not 50 mgs), 3 mol (not 3 mols).


Do not mix abbreviations and spelt-out units within units of measure.


Do not capitalize surnames that are used as units of measure.


Centrifugal force should be preferably expressed as ×g, rather than rpm.


L-amino acid, D-amino acid (i.e., LD in small caps).


Names for regional bioproducts should be written in non-italicized lowercase letters. The names should be explained in parenthesis when used first time in the abstract/text. (e.g., kimchi (Korean traditional fermented cabbages)).


Usage should be consistent within a paper.



It is hoped that this list will be useful during the final checking of your manuscript prior to submitting it to the journal for review. Ensure that the following items are present:

        One author designated as the corresponding author

        Telephone numbers, and E-mail address of the corresponding author


        All tables (including title, description, footnotes) and figures (separated from figure legends)

           are provided in a single file with the main text for initial submission.

        References are in the correct format for this journal.

        All references mentioned in the Reference list are cited in the text and vice versa.

Publication Ethics: The publication process at Bulletin of Biotechnology (Bull. Biotechnol.) is the basis of the improvement and dissemination of information objectively and respectfully. Therefore, the procedures in this process improves the quality of the studies. Peer-reviewed studies are the ones that support and materialize the scientific method. At this point, it is of utmost importance that all parties included in the publication process (authors, readers and researchers, publisher, reviewers and editors) comply with the standards of ethical considerations. The journal expects all parties to hold the following ethical responsibilities.

Ethical Responsibilities of Authors: The authors who submit their manuscripts to Bulletin of Biotechnology are expected to comply with the following ethical responsibilities:
Author(s) must submit original studies to the journal. If they utilize or use other studies, they must make the in-text and end-text references accurately and completely.
People who have not contributed to the study at the intellectual level should not be indicated as author.
If the manuscripts submitted to be published are subject of conflicting interests or relations, these must be explained.
During the review process of their manuscripts, author(s) may be asked to supply raw data. In such a case, author(s) should be ready to submit such data and information to the editorial and scientific boards.
Author(s) should document that they have the participants' consent and the necessary permissions related to the sharing and research/analysis of the data that are used.
Author(s) bears the responsibility to inform the editor of the journal or publisher if they happen to notice a mistake in their study which is in early release or publication process and to cooperate with the editors during the correction or withdrawal process.
Authors cannot submit their studies to multiple journals simultaneously. Each submission can be made only after the previous one is completed. A study published in another journal cannot be submitted to Bulletin of Biotechnology.
Author responsibilities are given in a study (e.g.: adding an author, reordering of author names) whose review process has begun cannot be changed.

Ethical Responsibilities of Editors: The editor and field editors of Bulletin of Biotechnology should hold the following ethical responsibilities that are based on the guides "COPE Code of Conduct and Best Practice Guidelines for Journal Editors" and "COPE Best Practice Guidelines for Journal Editors" published as open Access by Committee on Publication Ethics (COPE).

General Duties and Responsibilities: Editors are responsible for each study published in the Bulletin of Biotechnology. In this respect, the editors have the following roles and responsibilities:
• Making efforts to meet the demand for knowledge from readers and authors,
• Ensuring the continuous development of the journal,
• Managing the procedures aimed to improve the quality of the studies published in the journal,
• Supporting freedom of expression,
• Ensuring academic integrity,
• Following the procedures without making concessions on intellectual property rights and ethical standards,
• Being transparent and clear in issues that require correction or explanation.
Relationships with Readers: Editors must make decisions taking into consideration the knowledge, skills and expectations of all readers, researchers and practitioners need. They must also ensure that the published studies contribute to the literature and be original. Moreover, they must take notice of the feedback received from researchers and practitioners and provide explanatory and informative feedback.

Relationships with Authors: Editors have the following duties and responsibilities in their relations with authors:
• Editors must make positive or negative decisions about the studies' importance, originality, validity, clarity in wording and suitability with the journal's aims and objectives.
• Editors must accept the studies that are within the scope of the publication into the pre-review process unless there are serious problems with the study.
• Editors must not ignore positive suggestions made by reviewers unless there are serious problems with the study.
• New editors, unless there are serious issues, must not change the previous editor's decisions about the studies.
• “Blind Review and Review Process” must be published and editors must prevent possible diversions in the defined processes.
• Editors must publish an “Authors Guide” that is comprehensive enough in answering queries by authors. This guide must be updated regularly.
• Authors should be provided with explanatory and informative feedback.

Relationships with Reviewers: Editors have the following duties and responsibilities in their relations with reviewers:
• choose reviewers according to the subject of the study.
• provide the information and guidance reviewers may need during the review process.
• observe whether there are conflicting interests between reviewers and authors.
• keep the identities of reviewers confidential in a blind review.
• encourage the reviewers to review the manuscript in an unbiased, scientific and objective tone.
• evaluate reviewers regularly based on criteria like performance and timing.
• develop practices and policies that increase the performance of reviewers.
• take necessary steps to update the reviewer pool dynamically.
• prevent unkind and unscientific reviews.
• make effort to ensure the reviewer pool has a wide range.

Relationships with the Editorial Board: Editors must make sure that the members of the editorial board follow the procedures in accordance with the publication policies and guidelines, and must inform the members about the publication policies and developments. The editors must also train new members of the editorial board and provide the information they need. Moreover, editors must
• ensure that the members of the editorial board review the manuscripts in an unbiased and independent manner.
• select the new members of the editorial board from those who can contribute to the journal and are qualified enough.
• send manuscripts for review based on the subject of expertise of the editorial board members.
• regularly communicate with the editorial board.
• arrange regular meetings with the editorial board for the development of publication policies and the journal.

Relationships with the Journal's Owner and Publisher: The relationship between the editors and publisher is based on the principle of the independence of editors. All the decisions made by the editors are independent of the publisher and the owner of the journal as required by the agreement made between editors and publisher.

Editorial and Blind Review Processes: Editors are obliged to comply with the policies of “Blind Review and Process” stated in the journal's publication policies. Therefore, the editors ensure that each manuscript is reviewed in an unbiased, fair and timely manner.

Quality Assurance: Editors must make sure that articles in the journal are published in accordance with the publication policies of the journal and international standards.

Protection of Personal Information: Editors are supposed to protect the personal information related with the subjects or visuals in the studies being reviewed, and to reject the study if there is no documentation of the subjects' consent. Furthermore, editors are supposed to protect the personal information of the authors, reviewers and readers.

Encouraging Ethical Rules and Protection of Human and Animal Rights: Editors are supposed to protect human and animal rights in the studies being reviewed and must reject the experimental studies which do not have ethical and related committee’s approval about the population given in such studies.

Precautions against possible Abuse and Malpractice: Editors are supposed to take precautions against possible abuse and malpractice. They must conduct investigations meticulously and objectively in determining and evaluating complaints about such situations. They must also share the results of the investigation.

Ensuring Academic Integrity: Editors must make sure that the mistakes, inconsistencies or misdirections in studies are corrected quickly.

Protection of Intellectual Property Rights: Editors are responsible for protecting the intellectual property rights of all the articles published in the journal and the rights of the journal and author(s) in cases where these rights are violated. Also, editors must take the necessary precautions in order to prevent the content of all published articles from violating the intellectual property rights of other publications.

Constructiveness and Openness to Discussion: Editors must
• pay attention to the convincing criticism about studies published in the journal and must have a constructive attitude towards such criticism.
• grant the right of reply to the author(s) of the criticized study.
• not ignore or exclude the study that includes negative results.

Complaints: Editors must examine the complaints from authors, reviewers or readers and respond to them in an explanatory and enlightening manner.

Conflicting Interests: Editors, acknowledging that there may be conflicting interests between reviewers and other editors, guarantee that the publication process of the manuscripts will be completed in an independent and unbiased manner

Ethical Responsibilities of Reviewers: The fact that all manuscripts are reviewed through “Blind Review” has a direct influence on the publication quality. This process ensures confidentiality by an objective and independent review. The review process at Bulletin of Biotechnology is carried out on the principle of double-blind review. Reviewers do not contact the authors directly, and the reviews and comments are conveyed through the journal management system. In this process, the reviewer views on the evaluation forms and full texts are assigned to the author(s) by the editor. Therefore, the reviewers doing review work for Bulletin of Biotechnology are supposed to bear the following ethical responsibilities:
Reviewers must
• agree to review only in their subject of expertise.
• review in an unbiased and confidential manner.
• inform the editor of the journal if they think that they encounter a conflict of interests and decline to review the manuscript during the review process.
• dispose of the manuscripts they have reviewed in accordance with the principle of confidentiality after the review process. Reviewers can use the final versions of the manuscripts they have reviewed only after publication.
• review the manuscript objectively and only in terms of its content and ensure that nationality, gender, religious and political beliefs, and economic apprehension do not influence the review.
• review the manuscript in a constructive and kind tone, avoid making personal comments including hostility, slander and insult.
• review the manuscript they have agreed to review on time and in accordance with the ethical rules stated above.

Unethical Behaviour: Should you encounter any unethical act or content in Bulletin of Biotechnology apart from the ethical responsibilities listed above, please notify the journal.

The Journal does NOT charge a fee for submission, processing or publication from authors.