GEBELİKTE ANTİKOAGÜLAN KULLANIMI İLE İLİŞKİLİ POSTPARTUM HEMORAJİ VE SONRASINDA ASPİRASYON PNÖMONİSİ GELİŞEN VAKANIN YÖNETİMİ Management of Aspiration Pneumonia Case Occured After a Serious Post-partum Hemorrhage Related to Anticoagulant Treatment During Pregnancy

Yıl 2020, Cilt: 10 Sayı: 2, 245 - 248, 08.06.2020

Emre Başer Taylan Onat Melike Demir Çaltekin Demet Aydoğan Kırmızı Şiho Hidayet Mustafa Kara Ethem Serdar Yalvaç

Öz

ÖZET
Kalp kapak trombozunu önlemek için mekanik kalp kapaklı hastalarda yaşam boyu antikoagülan tedavi zorunludur.
Gebe kadında bu ilaçlar teratojenik etkilere ve kanama komplikasyonlarına neden olabilir. Bu yazıda,
antikoagülanlarla ilişkili doğum sonrası kanama gelişen ve daha sonra aspirasyon pnömonisi gelişen bir olgu
sunulmuştur.
Anahtar kelimeler: Antikoagülan tedavi; doğum sonrası kanama; aspirasyon pnömonisi
ABSTRACT
Life-long anticoagulation therapy is mandatory in patients with mechanical heart valve to prevent the valve
thrombosis. It may cause teratogenic effects and hemorrhage complications in the pregnant woman. In this
report, we present a case who developed post-partum haemorrhage related to anticoagulants and subsequently
developed aspiration pneumonia.
Keywords: Anticoagulant therapy; postpartum hemorrhage; aspiration pneumonia

Anahtar Kelimeler

GEBELİKTE ANTİKOAGÜLAN KULLANIMI İLE İLİŞKİLİ POSTPARTUM HEMORAJİ VE SONRASINDA ASPİRASYON PNÖMONİSİ GELİŞEN VAKANIN YÖNETİMİ Management of Aspiration Pneumonia Case Occured After a Serious Post-partum Hemorrhage Related to Anticoagulant Treatment During Pregnancy

Kaynakça

• 1. Chan WS, Anand S, Ginsberg JS. Anticoagulation of pregnant women with mechanical heart valves: a systematic review of the literature. Archives of internal medicine. 2000;160(2):191-6. 2. van Hagen IM, Roos-Hesselink JW, Ruys TP, Merz WM, Goland S, Gabriel H, et al. Pregnancy in Women With a Mechanical Heart Valve: Data of the European Society of Cardiology Registry of Pregnancy and Cardiac Disease (ROPAC). Circulation. 2015;132(2):132-42. 3. Garcez JD, Rosa VE, Lopes AS, Accorsi TA, Fernandes JR, Pomerantzeff PM, et al. Patient Management with Metallic Valve Prosthesis during Pregnancy and Postpartum Period. Arquivos brasileiros de cardiologia. 2015;105(4):426-9. 4. Nishimura RA, Otto CM, Bonow RO, Carabello BA, Erwin JP, 3rd, Guyton RA, et al. 2014 AHA/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. The Journal of thoracic and cardiovascular surgery. 2014;148(1):e1-e132. 5. Aguilera C, Agusti A. [Anticoagulation of pregnant women with mechanical heart valves]. Medicina clinica. 2003;121(19):755-6. 6. Hirsh J, Fuster V, Ansell J, Halperin JL. American Heart Association/American College of Cardiology Foundation guide to warfarin therapy. Circulation. 2003;107(12):1692-711. 7. Nishimura RA, Otto CM, Bonow RO, Carabello BA, Erwin JP, 3rd, Fleisher LA, et al. 2017 AHA/ACC Focused Update of the 2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Journal of the American College of Cardiology. 2017;70(2):252-89. 8. Castellano JM, Narayan RL, Vaishnava P, Fuster V. Anticoagulation during pregnancy in patients with a prosthetic heart valve. Nature reviews Cardiology. 2012;9(7):415-24. 9. Kawamata K, Neki R, Yamanaka K, Endo S, Fukuda H, Ikeda T, et al. Risks and pregnancy outcome in women with prosthetic mechanical heart valve replacement. Circulation journal : official journal of the Japanese Circulation Society. 2007;71(2):211-3. 10. Panduranga P, El-Deeb M, Jha C. Mechanical Prosthetic Valves and Pregnancy: A therapeutic dilemma of anticoagulation. Sultan Qaboos University medical journal. 2014;14(4):e448-54.