Florür ve Florür Ürünlerine İlişkin Perspektifler Konusunda İki Üniversite Grubunun Görüşlerinin Karşılaştırılması

Öz

Dünyada diş çürüğünü önlemede en yaygın kullanılan madde hala florürdür, ancak son yıllarda florür kullanımına karşı endişeler ve olumsuz tutumlar ortaya çıkmaktadır. Çalışmanın amacı Burdur Mehmet Akif Ersoy (MAKU) ve Mississippi Üniversitesi (MSU) öğrencilerinin florür hakkındaki bilgi ve tutumlarını karşılaştırmaktır. Çalışma MAKU’dan 110 ve MSU’dan 107 olmak üzere toplam 217 katılımcı ile gerçekleştirilmiştir. 15 sorudan oluşan ankette katılımcılara demografik bilgileri, florürlü diş macunları ve florür uygulamaları, florürün diş sağlığı üzerine etkileri hakkındaki bilgi ve görüşleri sorulmuştur. MAKU grubu ağız ve diş sağlığı hakkındaki bilgilerin doğruluğunu araştırmayı tercih ederken (%45,45) ve florür hakkındaki spekülatif bilgilere inanmazken (%46,36), MSU grubu ağız ve diş sağlığı hakkındaki bilgilere daha şüpheci yaklaşmış (%71,96) ve florür hakkındaki olumsuz bilgilere daha çok inandıklarını belirtmişlerdir (%43,92). Çalışma, kültürel farklılıkların florür hakkındaki algılar üzerindeki etkisini ortaya koymaktadır.

Anahtar Kelimeler

• Florür
• kültürel farklılık
• bakış açıları
• çürüme

Comparison of the Views of Two University Groups on Fluoride and Fluoride Products

Abstract

The most widely used substance in the world to prevent tooth decay is still fluoride, but in recent years there have been concerns and negative attitudes towards the use of fluoride. The aim of the study was to compare the knowledge and attitudes of Burdur Mehmet Akif Ersoy (MAKU) and Mississippi University (MSU) students about fluoride. The study was conducted with a total of 217 participants, 110 from MAKU and 107 from MSU. The participants were asked about demographic information, fluoride toothpastes and fluoride applications, and their knowledge and opinions about the effects of fluoride on dental health in the 15-question survey. While the MAKU group preferred to investigate the accuracy of information about oral and dental health (45.45%) and did not believe speculative information about fluoride (46.36%), the MSU group was more skeptical of information about oral and dental health (71. 96%) and stated that they believed negative information about fluoride more (43.92%). The study revealed the impact of cultural differences on perceptions about fluoride.

Keywords

• Fluoride
• cultural difference
• perspectives
• decay

References

1. Abduweli-Uyghurturk, D., Goin, D. E., Martinez-Mier, E. A., Woodruff, T. J., & DenBesten, P. K. (2020). Maternal and fetal exposures to fluoride during mid-gestation among pregnant women in northern California. Environmental health: a global access science source, 19(1), 38. https://doi.org/10.1186/s12940-020-00581-2
2. Ak, A.T., Aksoy, H., & Özdaş, D.Ö. (2018). Türk ailelerinin florlu diş macunu ve topikal flor uygulamaları hakkında bilgi ve görüşlerinin değerlendirilmesi: Pilot çalışma. Ege Üniversitesi Diş Hekimliği Fakültesi Dergisi, 39(3), 160-164. https://doi.org/10.5505/eudfd.2018.48568
3. Akbar, A. A., Al-Sumait, N., Al-Yahya, H., Sabti, M. Y., & Qudeimat, M. A. (2018). Knowledge, attitude, and barriers to fluoride application as a preventive measure among oral health care providers. International Journal of Dentistry, 8908924. https://doi.org/10.1155/2018/8908924
4. Aoun, A., Darwiche, F., Al Hayek, S., & Doumit, J. (2018). The fluoride debate: The pros and cons of fluoridation. Preventive Nutrition and Food Science, 23(3), 171–180. https://doi.org/10.3746/pnf.2018.23.3.171
5. Aren, G. (2020). Koruyucu diş hekimliğinde florürlerin kullanımında değişen bakış açısı. Selcuk Dental Journal, 7(1), 113-117. https://doi.org/10.15311/selcukdentj.413680
6. Bhatnagar, M., Rao, P., Saxena, A., Meena, P., Barbar, S., Chouhan, A., & Udaipur, S. V. (2006). Biochemical changes in brain and other tissues of young adult female mice from fluoride in their drinking water. Fluoride, 39, 280-284.
7. Bissada N. F. (1994). Symptomatology and clinical features of hypersensitive teeth. Archives of Oral Biology, 39, 31S–32S. https://doi.org/10.1016/0003-9969(94)90185-6
8. Buzalaf, M. A. R., & Whitford, G. M. (2011). Fluoride metabolism. Monographs in Oral Science, 22, 20-36. https://doi.org/10.1159/000325107

9. Choi, A. L., Sun, G., Zhang, Y., & Grandjean, P. (2012). Developmental fluoride neurotoxicity: a systematic review and meta-analysis. Environmental Health Perspectives, 120(10), 1362–1368. https://doi.org/10.1289/ehp.1104912
10. Cury, J. A., & Tenuta, L. M. (2014). Evidence-based recommendation on toothpaste use. Brazilian Oral Research, 28, 1–7. https://doi.org/10.1590/S1806-83242014.50000001
11. DePaula, C. A., Abjornson, C., Pan, Y., Kotha, S. P, Koike, K., & Guzelsu, N. (2002). Changing the structurally effective mineral content of bone with in vitro fluoride treatment. Journal of Biomechanics, 35, 355-361. https://doi.org/10.1016/S0021-9290(01)00219-6
12. Ekanayake L, & Van der Hoek W. (2003). Prevalance and distribution of enamel defects and dental caries in a region with different concentrations of fluoride in drinking water in Sri Lanka. International Dental Journal, 53, 243-8. ttps://doi.org/10.1111/j.1875-595x.2003.tb00752.x.
13. Ellwood, R. P., Blinkhorn, A. S., & Davies, R. M. (1998). Fluoride: how to maximize the benefits and minimize the risks. Dental Update, 25(9), 365–372.
14. Everett, E. T. (2011). Fluoride’s effects on the formation of teeth and bones, and the influence of genetics. Journal of Dental Research, 90(5), 552–560. https://doi.org/10.1177/0022034510384626
15. Fagrell, T. G., Lingström, P., Olsson, S., Steiniger, F., & Norén, J. G. (2008). Bacterial invasion of dentinal tubules beneath apparently intact but hypomineralized enamel in molar teeth with molar incisor hypomineralization. International Journal of Paediatric Dentistry, 18(5), 333–340. https://doi.org/10.1111/j.1365-263X.2007.00908.x
16. Featherstone, J. D. (1999). Prevention and reversal of dental caries: role of low level fluoride. Community Dentistry and Oral Epidemiology, 27(1), 31–40. https://doi.org/10.1111/j.1600-0528.1999.tb01989.x
17. Fuller, R., Landrigan, P. J., Balakrishnan, K., Bathan, G., Bose-O’Reilly, S., Brauer, M., … Yan, C. (2022). Pollution and health: a progress update. The Lancet. Planetary Health, 6(6), e535–e547. https://doi.org/10.1016/S2542-5196(22)00090-0
18. Gabler, W. L. (1968). Absorption of fluoride through the oral mucosa of rats. Archives of Oral Biology, 13(6), 619–623. https://doi.org/10.1016/0003-9969(68)90140-4
19. Ganss, C., Schlueter, N., Preiss, S., & Klimek, J. (2009). Tooth brushing habits in uninstructed adults--frequency, technique, duration and force. Clinical Oral Investigations, 13(2), 203–208. https://doi.org/10.1007/s00784-008-0230-8
20. Goff, S. L., Gilson, C. F., DeCou, E., Dick, A. W., Geissler, K. H., Dalal, M., & Kranz, A. M. (2024). Barriers and facilitators to optimal fluoride varnish application. Academic Pediatrics, 24(5), 755–764. https://doi.org/10.1016/j.acap.2023.09.018
21. Grandjean, P., & Landrigan, P. J. (2014). Neurobehavioural effects of developmental toxicity. The Lancet. Neurology, 13(3), 330–338. https://doi.org/10.1016/S1474-4422(13)70278-3
22. Heath, K., Singh, V., Logan, R., & McIntyre, J. (2001). Analysis of fluoride levels retained intraorally or ingested following routine clinical applications of topical fluoride products. Australian Dental Journal, 46(1), 24–31. https://doi.org/10.1111/j.1834-7819.2001.tb00270.x
23. Hellwig, E., & Lennon, A. M. (2004). Systemic versus topical fluoride. Caries Research, 38(3), 258–262. https://doi.org/10.1159/000077764
24. Hicks, J., Garcia-Godoy, F., & Flaitz, C. (2004). Biological factors in dental caries enamel structure and the caries process in the dynamic process of demineralization and remineralization (part 2). The Journal of Clinical Pediatric Dentistry, 28(2), 119–124. https://doi.org/10.17796/jcpd.28.2.617404w302446411
25. Kumar, J. V., & Green, E. L. (1998). Recommendations for fluoride use in children. A review. The New York State Dental Journal, 64(2), 40–47. Retrieved from https://pubmed.ncbi.nlm.nih.gov/9542393/
26. Kundu, H., Basavaraj, P., Singla, A., Gupta, R., Singh, K., & Jain, S. (2015). Effect of fluoride in drinking water on children’s intelligence in high and low fluoride areas of Delhi. J Indian Assoc Public Health Dent, 13, 116-121 https://doi.org/10.4103/2319-5932.159043
27. Limeback, H. (1999). A re-examination of the pre-eruptive and post-eruptive mechanism of the anti-caries effects of fluoride: is there any anti-caries benefit from swallowing fluoride?. Community Dentistry and Oral Epidemiology, 27(1), 62–71. https://doi.org/10.1111/j.1600-0528.1999.tb01993.x
28. McKAY, F. S. (1948). Mass control of dental caries through the use of domestic water supplies containing fluorine. American Journal of Public Health and the Nation’s Health, 38(6), 828–832. https://doi.org/10.2105/ajph.38.6.828
29. McKAY, F. S. (1952). The study of mottled enamel (dental fluorosis). Journal of the American Dental Association, 44(2), 133–137. https://doi.org/10.14219/jada.archive.1952.0057
30. Mousny, M., Omelon, S., Wise, L., Everett, E. T., Dumitriu, M., Holmyard, D. P., Banse, X., Devogelaer, J. P., & Grynpas, M. D. (2008). Fluoride effects on bone formation and mineralization are influenced by genetics. Bone, 43(6), 1067–1074. https://doi.org/10.1016/j.bone.2008.07.248
31. Ottappilakkil, H., & Perumal, E. (2025). Fluoride Exposure Modulates Skeletal Development and Mineralization in Zebrafish Larvae. Environmental Toxicology, 10.1002/tox.24474. Advance online publication. https://doi.org/10.1002/tox.24474
32. Padilla-Reyes, D. A., Dueñas-Moreno, J., Mahlknecht, J., Mora, A., Kumar, M., Ornelas-Soto, N., Mejía-Avendaño, S., Navarro-Gómez, C. J., & Bhattacharya, P. (2024). Arsenic and fluoride in groundwater triggering a high risk: Probabilistic results using Monte Carlo simulation and species sensitivity distribution. Chemosphere, 359, 142305. https://doi.org/10.1016/j.chemosphere.2024.142305
33. Rodd, H. D., Boissonade, F. M., & Day, P. F. (2007). Pulpal status of hypomineralized permanent molars. Pediatric Dentistry, 29(6), 514–520.
34. Sebastian, S. T., & Sunitha, S. (2015). A cross-sectional study to assess the intelligence quotient (IQ) of school going children aged 10-12 years in villages of Mysore district, India with different fluoride levels. Journal of the Indian Society of Pedodontics and Preventive Dentistry, 33(4), 307–311. https://doi.org/10.4103/0970-4388.165682
35. Shivaprakash, P. K., Ohri, K., & Noorani, H. (2011). Relation between dental fluorosis and intelligence quotient in school children of Bagalkot district. Journal of the Indian Society of Pedodontics and Preventive Dentistry, 29(2), 117–120. https://doi.org/10.4103/0970-4388.84683
36. Shivarajashankara, Y. M., Shivashankara, A. R., Gopalakrishna-Bhat, P., Muddanna-Rao, S., & Hanumanth-Rao, S. (2002). Histological changes in the brain of young fluoride-intoxicated rats, Karnataka, India. Fluoride Res, 35(1), 12-21.
37. Sköld-Larsson, K., Modéer, T., & Twetman, S. (2000). Fluoride concentration in plaque in adolescents after topical application of different fluoride varnishes. Clinical Oral Investigations, 4(1), 31–34. https://doi.org/10.1007/s007840050110
38. Solanki, Y. S., Agarwal, M., Gupta, A. B., Gupta, S., & Shukla, P. (2022). Fluoride occurrences, health problems, detection, and remediation methods for drinking water: A comprehensive review. The Science of the Total Environment, 807(Pt 1), 150601. https://doi.org/10.1016/j.scitotenv.2021.150601
39. Tenuta, L. M., & Cury, J. A. (2010). Fluoride: its role in dentistry. Brazilian Oral Research, 24, 9–17. https://doi.org/10.1590/s1806-83242010000500003
40. Turska-Szybka, A., Piotrkowicz, Z., Prokopczyk, M., Olczak-Kowalczyk, D., Sierakowski, M., Gozdowski, D., & Tomczyk, J. (2024). Concentration of Fluoride in Saliva After Fluoride Gel Application: A Randomised Clinical Trial. International Dental Journal, 74(4), 794–800. https://doi.org/10.1016/j.identj.2024.01.005
41. Vellappally, S., Naik, S., Al-Kheraif, A. A., Alayadi, H., Alageel, O., Alsarani, M. M., Ramadoss, R., Thomas, N. G., Alateek, M., & Anil, S. (2024). Fluoride Concentrations in Different Brands of Toothpaste Marketed in Saudi Arabia. International Journal of Dental Hygiene, 10.1111/idh.12855. Advance online publication. https://doi.org/10.1111/idh.12855
42. Veneri, F., Vinceti, M., Generali, L., Giannone, M. E., Mazzoleni, E., Birnbaum, L. S., Consolo, U., & Filippini, T. (2023). Fluoride exposure and cognitive neurodevelopment: Systematic review and dose-response meta-analysis. Environmental Research, 221, 115239. https://doi.org/10.1016/j.envres.2023.115239
43. Wang, J., Ge, Y., Ning, H., & Wang, S. (2004). Effects of High Fluoride and Low Iodine on Biochemical Indexes of the Brain and Learning-Memory of Offspring Rats. Fluoride 37(3), 201-208.
44. Wang, S. X., Wang, Z. H., Cheng, X. T., Li, J., Sang, Z. P., Zhang, X. D., … Wang, Z. Q. (2007). Arsenic and fluoride exposure in drinking water: children’s IQ and growth in Shanyin county, Shanxi province, China. Environmental Health Perspectives, 115(4), 643–647. https://doi.org/10.1289/ehp.9270
45. Whitford, G. M., & Pashley, D. H. (1984). Fluoride absorption: the influence of gastric acidity. Calcified Tissue International, 36(3), 302–307. https://doi.org/10.1007/BF02405334
46. Yang, S., Yu, S., Du, Y., Feng, Z., Jiao, X., Li, Q., Wu, J., Sun, L., Zuo, J., Fu, X., Li, Z., Huang, H., Zhou, G., Yu, F., & Ba, Y. (2024). Correlations between bone metabolism biomarkers and fluoride exposure in adults and children. Journal of Trace Elements in Medicine and Biology: Organ of the Society for Minerals and Trace Elements (GMS), 84, 127419. https://doi.org/10.1016/j.jtemb.2024.127419