Abdominal BT ile Mide Antrumu Duvar Kalınlığının Analizi: Benin ve Malin Patolojileri Ayırt Etmede Yüksek Tanısal Doğruluk

Öz

Amaç: Mide kanserinin mümkün olan en erken aşamada teşhis edilmesi ve uygun tedaviye başlanması, hastaların uzun süreli sağkalımı için hayati bir önem taşımaktadır. Bu çalışmada, abdominal bilgisayarlı tomografi (BT) tetkikinde ölçülen antrum duvar kalınlığının endoskopik ve patolojik değerlendirme sonuçlarıyla karşılaştırmalı analizi gerçekleştirilmiştir. Amacımız benin ve malin durumları ayırt edebilecek optimal duvar kalınlığı kesim değerini belirleyerek klinik uygulamalarda tanı sürecini hızlandırmak ve doğru tedavi yöntemlerinin belirlenmesine yardımcı olmaktır. Yöntem: Şubat 2023 ile Ocak 2024 tarihleri arasında, endoskopik olarak antrum duvar örneklemesi yapılmış ve endoskopiden önceki veya sonraki 2 ay içinde abdominal BT tetkiki gerçekleştirilmiş olan 213 hasta çalışmaya dahil edilmiştir. Hastaların yaş, cinsiyet gibi demografik özellikleri ile birlikte abdominal BT tetkiklerinden ölçülen antrum duvar kalınlıkları, histopatolojik sonuçlarla retrospektif olarak karşılaştırılmıştır. Ayrıca benin ile malin patolojilerin ayrımında ROC analizi kullanılarak kesim değeri belirlenmiş, duyarlılık ve özgüllük oranları hesaplanmıştır. Bulgular: Çalışmaya dahil edilen 213 hastanın 126’sı erkek, 87’si kadındır ve ortalama yaşları 60.8 yıldır. Bu hastaların 94’ü (60 erkek, 34 kadın; ortalama yaş 66.1 yıl) malin, 119’u (66 erkek, 53 kadın; ortalama yaş 56.6 yıl) ise benin olarak değerlendirilmiştir (p < 0.001). Antrum kalınlığı açısından malin ve benin durumların ayrımı için 12 mm kesim değeri kullanıldığında, duyarlılık %100 ve özgüllük %95.7 olarak bulunmuştur. Sonuç: Optimal koşullarda elde edilen abdominal BT tetkiklerinde yapılan antrum duvar kalınlığı ölçümü, bu bölgeden kaynaklanabilecek benin ve malin patolojilerin ayrımı konusunda önemli bilgiler sağlamakta, böylece mide kanserinin erken teşhisinde ve tedavi sürecinde kritik bir rol oynamaktadır.

Anahtar Kelimeler

• Antrum Duvar Kalınlığı
• Bilgisayarlı Tomografi
• Endoskopi
• Mide Kanseri

Analysis of Gastric Antrum Wall Thickness by Abdominal CT: High Diagnostic Accuracy in Differentiating Benign and Malignant Pathologie

Öz

are crucial for achieving long-term survival in patients. In this study, we performed a comparative analysis of the antral wall thickness measured by abdominal computed tomography (CT) with endoscopic and pathological evaluation results. The objective of this study is to determine the optimal cut-off value for wall thickness that can distinguish between benign and malignant conditions, thereby accelerating the diagnostic process in clinical practice and aiding in the determination of appropriate treatment strategies. Methods: A total of 213 patients who underwent endoscopic antral wall sampling between February 2023 and January 2024, and who had an abdominal CT scan performed within two months before or after the endoscopy were included in this study. The patients’ demographic characteristics, including age and gender, along with antral wall thickness measurements obtained from abdominal CT scans, were retrospectively compared with histopathological results. Furthermore, a cut-off value was determined using ROC analysis for differentiating benign from malignant pathologies, and sensitivity and specificity rates were calculated. Results: A total of 213 patients were included in the study, comprising 126 males and 87 females, with a mean age of 60.8 years. Among these patients, 94 (60 males, 34 females; mean age 66.1 years) were classified as malignant, while 119 (66 males, 53 females; mean age 56.6 years) were classified as benign (p < 0.001). Using a cut-off value of 12 mm for antral wall thickness to differentiate between benign and malignant conditions, the sensitivity was 100%, and the specificity was 95.7%. Conclusion: The measurement of antral wall thickness using abdominal CT under optimal conditions provides significant information for differentiating benign and malignant pathologies originating from this region. This measurement plays a critical role in the early diagnosis and treatment of gastric cancer.

Anahtar Kelimeler

• Antral Wall Thickness
• Computed Tomography
• Endoscopy
• Gastric Cancer

Kaynakça

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