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Çocuklarda İmmün Trombositopeni ile Birlikte Görülen Primer Aktif Epstein-Barr Virüs Enfeksiyonu - İmmün Trombositopeninin Nadir Bir Tetikleyici Faktörü: İki Olgu Sunumu

Yıl 2024, Cilt: 11 Sayı: 1, 183 - 186, 27.03.2024
https://doi.org/10.34087/cbusbed.1433575

Öz

İmmün trombositopeni (ITP), çocukluk çağında izole trombositopeni ile karakterize bir trombositopeni nedenidir. Epstein barr virüs enfeksiyonu (EBV) ITP için tetikleyici bir faktör olabilecek hafif ve komplikasyonsuz bir hastalıktır. Burada, Epstein barr virüs enfeksiyonuna ikincil ITP gelişen iki olgu tartışılmıştır.

Etik Beyan

Informed Consent: Informed consent was taken prior to writing this case report from the patient’s parents.

Destekleyen Kurum

This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors.

Kaynakça

  • 1. Rodeghiero F, Stasi R, Gernsheimer T, et al. Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group. Blood 2009; 113:2386–2393.
  • 2. Correia S, Bridges R, Wegner F, et al. Sequence Variation of Epstein-Barr Virus: Viral Types, Geography, Codon Usage, and Diseases. J Virol 2018; 92: e01132-18.
  • 3. Pipp ML, Means ND, Sixbey JW, Morris KL, Gue CL, Baddour LM. Acute Epstein- Barr virus infection complicated by severe thrombocytopenia. Clin Infect Dis 1997; 25:1237–9.
  • 4. Zeller B, Rajantie J, Hedlund-Treutiger I, et al. Childhood idiopathic thrombocytopenic purpura in the Nordic countries: epidemiology and predictors of chronic disease. Acta Paediatr 2005; 94:178-84.
  • 5. Chiang MR, Wei CC, Muo CS, Fu LS, Li TC, Kao CH. Association of primary immune thrombocytopenia and common allergic diseases among children. Pediatr Res 2015; 77:597-601.
  • 6. Ebell MH. Epstein-Barr virus infectious mononucleosis. Am Fam Physician 2004; 70:1279-87.
  • 7. Elalfy MS, Nugent D. Viruses, anti-viral therapy, and viral vaccines in children with immune thrombocytopenia. Semin Hematol 2016; 53:70-72.
  • 8. Nielsen TR, Rostgaard K, Nielsen NM, et al. Multiple sclerosis after infectious mononucleosis. Arch Neurol 2007; 64:72-75.
  • 9. Norris PAA, Kaur G, Lazarus AH. New insights into IVIg mechanisms and alternatives in autoimmune and inflammatory diseases. Curr Opin Hematol 2020; 27:392-398

Primary Active Epstein-Barr Virus Infection Coexisting with Immune Thrombocytopenia in Children-A Rare Trigger Factor of Immun Thrombocytopenia: Two Case Reports

Yıl 2024, Cilt: 11 Sayı: 1, 183 - 186, 27.03.2024
https://doi.org/10.34087/cbusbed.1433575

Öz

Immune thrombocytopenia (ITP) is a reason of thrombocytopenia that is characterized by isolated thrombocytopenia in childhood. Epstein barr virus infection (EBV) is a mildly and uncomplicated ailment that might be a trigger factor for ITP. Here, we discuss two cases with ITP secondary Epstein barr virus infection.

Kaynakça

  • 1. Rodeghiero F, Stasi R, Gernsheimer T, et al. Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group. Blood 2009; 113:2386–2393.
  • 2. Correia S, Bridges R, Wegner F, et al. Sequence Variation of Epstein-Barr Virus: Viral Types, Geography, Codon Usage, and Diseases. J Virol 2018; 92: e01132-18.
  • 3. Pipp ML, Means ND, Sixbey JW, Morris KL, Gue CL, Baddour LM. Acute Epstein- Barr virus infection complicated by severe thrombocytopenia. Clin Infect Dis 1997; 25:1237–9.
  • 4. Zeller B, Rajantie J, Hedlund-Treutiger I, et al. Childhood idiopathic thrombocytopenic purpura in the Nordic countries: epidemiology and predictors of chronic disease. Acta Paediatr 2005; 94:178-84.
  • 5. Chiang MR, Wei CC, Muo CS, Fu LS, Li TC, Kao CH. Association of primary immune thrombocytopenia and common allergic diseases among children. Pediatr Res 2015; 77:597-601.
  • 6. Ebell MH. Epstein-Barr virus infectious mononucleosis. Am Fam Physician 2004; 70:1279-87.
  • 7. Elalfy MS, Nugent D. Viruses, anti-viral therapy, and viral vaccines in children with immune thrombocytopenia. Semin Hematol 2016; 53:70-72.
  • 8. Nielsen TR, Rostgaard K, Nielsen NM, et al. Multiple sclerosis after infectious mononucleosis. Arch Neurol 2007; 64:72-75.
  • 9. Norris PAA, Kaur G, Lazarus AH. New insights into IVIg mechanisms and alternatives in autoimmune and inflammatory diseases. Curr Opin Hematol 2020; 27:392-398
Toplam 9 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Klinik Tıp Bilimleri (Diğer)
Bölüm Olgu Sunumu
Yazarlar

Şule Gökçe 0000-0003-3392-4990

Merve Tosyalı 0000-0002-7920-1491

Aykut Şafaklı 0009-0003-5015-4964

Rıza Yıldırım 0009-0000-2675-1150

Necla Burcu Koçer Ahmadov 0009-0003-5797-5714

Gizem Tunçalp 0009-0007-2318-5115

Nur Bostancı 0009-0001-5516-2088

Ayla Mammadova 0009-0002-1783-3546

Elif Gökçe Çelebi 0009-0001-4377-7843

Nida Nur Şahin 0009-0009-3595-8685

Çağla Türksönmez 0009-0005-5917-1220

Aylin Erol 0009-0007-3251-7222

Hüseyin Orkun Köse 0009-0001-9403-4775

Feyza Umay Koç 0000-0002-5891-8506

Yayımlanma Tarihi 27 Mart 2024
Gönderilme Tarihi 8 Şubat 2024
Kabul Tarihi 25 Mart 2024
Yayımlandığı Sayı Yıl 2024 Cilt: 11 Sayı: 1

Kaynak Göster

APA Gökçe, Ş., Tosyalı, M., Şafaklı, A., Yıldırım, R., vd. (2024). Primary Active Epstein-Barr Virus Infection Coexisting with Immune Thrombocytopenia in Children-A Rare Trigger Factor of Immun Thrombocytopenia: Two Case Reports. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, 11(1), 183-186. https://doi.org/10.34087/cbusbed.1433575
AMA Gökçe Ş, Tosyalı M, Şafaklı A, Yıldırım R, Koçer Ahmadov NB, Tunçalp G, Bostancı N, Mammadova A, Çelebi EG, Şahin NN, Türksönmez Ç, Erol A, Köse HO, Umay Koç F. Primary Active Epstein-Barr Virus Infection Coexisting with Immune Thrombocytopenia in Children-A Rare Trigger Factor of Immun Thrombocytopenia: Two Case Reports. CBU-SBED. Mart 2024;11(1):183-186. doi:10.34087/cbusbed.1433575
Chicago Gökçe, Şule, Merve Tosyalı, Aykut Şafaklı, Rıza Yıldırım, Necla Burcu Koçer Ahmadov, Gizem Tunçalp, Nur Bostancı, Ayla Mammadova, Elif Gökçe Çelebi, Nida Nur Şahin, Çağla Türksönmez, Aylin Erol, Hüseyin Orkun Köse, ve Feyza Umay Koç. “Primary Active Epstein-Barr Virus Infection Coexisting With Immune Thrombocytopenia in Children-A Rare Trigger Factor of Immun Thrombocytopenia: Two Case Reports”. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 11, sy. 1 (Mart 2024): 183-86. https://doi.org/10.34087/cbusbed.1433575.
EndNote Gökçe Ş, Tosyalı M, Şafaklı A, Yıldırım R, Koçer Ahmadov NB, Tunçalp G, Bostancı N, Mammadova A, Çelebi EG, Şahin NN, Türksönmez Ç, Erol A, Köse HO, Umay Koç F (01 Mart 2024) Primary Active Epstein-Barr Virus Infection Coexisting with Immune Thrombocytopenia in Children-A Rare Trigger Factor of Immun Thrombocytopenia: Two Case Reports. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 11 1 183–186.
IEEE Ş. Gökçe, “Primary Active Epstein-Barr Virus Infection Coexisting with Immune Thrombocytopenia in Children-A Rare Trigger Factor of Immun Thrombocytopenia: Two Case Reports”, CBU-SBED, c. 11, sy. 1, ss. 183–186, 2024, doi: 10.34087/cbusbed.1433575.
ISNAD Gökçe, Şule vd. “Primary Active Epstein-Barr Virus Infection Coexisting With Immune Thrombocytopenia in Children-A Rare Trigger Factor of Immun Thrombocytopenia: Two Case Reports”. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 11/1 (Mart 2024), 183-186. https://doi.org/10.34087/cbusbed.1433575.
JAMA Gökçe Ş, Tosyalı M, Şafaklı A, Yıldırım R, Koçer Ahmadov NB, Tunçalp G, Bostancı N, Mammadova A, Çelebi EG, Şahin NN, Türksönmez Ç, Erol A, Köse HO, Umay Koç F. Primary Active Epstein-Barr Virus Infection Coexisting with Immune Thrombocytopenia in Children-A Rare Trigger Factor of Immun Thrombocytopenia: Two Case Reports. CBU-SBED. 2024;11:183–186.
MLA Gökçe, Şule vd. “Primary Active Epstein-Barr Virus Infection Coexisting With Immune Thrombocytopenia in Children-A Rare Trigger Factor of Immun Thrombocytopenia: Two Case Reports”. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, c. 11, sy. 1, 2024, ss. 183-6, doi:10.34087/cbusbed.1433575.
Vancouver Gökçe Ş, Tosyalı M, Şafaklı A, Yıldırım R, Koçer Ahmadov NB, Tunçalp G, Bostancı N, Mammadova A, Çelebi EG, Şahin NN, Türksönmez Ç, Erol A, Köse HO, Umay Koç F. Primary Active Epstein-Barr Virus Infection Coexisting with Immune Thrombocytopenia in Children-A Rare Trigger Factor of Immun Thrombocytopenia: Two Case Reports. CBU-SBED. 2024;11(1):183-6.