NON-PROPORTIONAL HAZARDS WITH APPLICATION TO KIDNEY TRANSPLANT DATA

Yıl 2007, , 55 - 63, 01.02.2007

Emel Başar

https://doi.org/10.1501/Commua1_0000000196

Öz

The Cox proportional hazards (PH) model is the popular methodfor modelling censored survival data.Cox PH model is the proportionality of hazards in which the hazard ratiois linear in the covariates. However this assumption may not hold in somesurvival studies. Therefore, diğerent non-parametric regression methods havebeen proposed to estimate the hazard ratio as a function of time when theproportionality of hazards can not be assumed.In this study a piecewisemodel and a non-parametric regression spline model have been considered forthe non-proportional hazards. The models have been illustrated with kidneytransplant data

Anahtar Kelimeler

Cox regression, Proportional hazards, Regression splines, Survivalanalysis

Kaynakça

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• E-mail address : [e-mail]