Review

A Review of the Effect of Progesterone Use on Miscarriage in Early Pregnancy Bleeding

Volume: 2 Number: 2 June 30, 2025
EN

A Review of the Effect of Progesterone Use on Miscarriage in Early Pregnancy Bleeding

Abstract

Pregnancy-related psychological and physiological issues can arise from treating impending miscarriage, miscarriage, and repeated pregnancy loss. Treatment is challenging since miscarriage and recurrent pregnancy loss have no obvious etiopathogenesis and are caused by a variety of causes. The pregesterone derivatives utilized in treatment, their administration method, length, and which derivative works best for treating the condition are all unclear. Threatened abortion, spontaneous abortion, incomplete abortion, and full abortion are the different categories of miscarriages.The basis for this classification is whether cervical patency is present or not. Threatened miscarriage is a clinical condition where there is no cervical patency and accompanying hemorrhage. Recurrent pregnancy loss is another term for three or more miscarriages. There are two types of progestogens: synthetic and natural. Progestogens differ from one another in their potency, modes of action, and modes of administration. The purpose of this review was to examine the advantages, administration techniques, length of administration, and statistics related to the use of progestogens in cases of recurrent pregnancy loss and impending miscarriage.

Keywords

Supporting Institution

no

Project Number

1

Ethical Statement

Ethical approval was not received for the compilation prepared from open platforms.

Thanks

no

References

  1. Lai TJ, Teng SW, Chang CK, Huang CY. Progesterone in Pregnancy: Evidence-Based Strategies to Reduce Miscarriage and Enhance Assisted Reproductive Technology. Med Sci Monit. 2024 Mar 8;30:e943400. doi: 10.12659/MSM.943400.
  2. Tuuli MG, Norman SM, Odibo AO, Macones GA, Cahill AG. Perinatal outcomes in women with subchorionic hematoma: a systematic review and meta-analysis. Obstet Gynecol. 2011 May;117(5):1205-1212. doi: 10.1097/AOG.0b013e31821568de.
  3. Csapo AI, Pulkkinen MO, Ruttner B, Sauvage JP, Wiest WG. The significance of the human corpus luteum in pregnancy maintenance. I. Preliminary studies. Am J Obstet Gynecol. 1972 Apr 15;112(8):1061-7. doi: 10.1016/0002-9378(72)90181-0.
  4. Swyer GI, Daley D. Progesterone implantation in habitual abortion. Br Med J. 1953 May 16;1(4819):1073-7. doi: 10.1136/bmj.1.4819.1073.
  5. Van der Linden M, Buckingham K, Farquhar C, Kremer JA, Metwally M. Luteal phase support for assisted reproduction cycles. Cochrane Database Syst Rev. 2015 Jul 7;2015(7):CD009154. doi: 10.1002/14651858.CD009154.pub3.
  6. Deng Y, Chen C, Chen S, Mai G, Liao X, Tian H, Liu W, Ji S, Liu Y, Gao J, Luo S. Baseline Levels of Serum Progesterone and the First Trimester Pregnancy Outcome in Women with Threatened Abortion: A Retrospective Cohort Study. Biomed Res Int. 2020 Mar 2;2020:8780253. doi: 10.1155/2020/8780253.
  7. Osmanağaoğlu MA, Erdoğan I, Eminağaoğlu S, Karahan SC, Ozgün S, Can G, Bozkaya H. The diagnostic value of beta-human chorionic gonadotropin, progesterone, CA125 in the prediction of abortions. J Obstet Gynaecol. 2010 Apr;30(3):288-93. doi: 10.3109/01443611003605286.
  8. Bender Atik R, Christiansen OB, Elson J, Kolte AM, Lewis S, Middeldorp S, Nelen W, Peramo B, Quenby S, Vermeulen N, Goddijn M. ESHRE guideline: recurrent pregnancy loss. Hum Reprod Open. 2018 Apr 6;2018(2):hoy004. doi: 10.1093/hropen/hoy004.

Details

Primary Language

English

Subjects

Clinical Sciences (Other)

Journal Section

Review

Publication Date

June 30, 2025

Submission Date

December 11, 2024

Acceptance Date

April 23, 2025

Published in Issue

Year 2025 Volume: 2 Number: 2

APA
Taşkıran, D., & Kolsuz, S. (2025). A Review of the Effect of Progesterone Use on Miscarriage in Early Pregnancy Bleeding. Cerasus Journal of Medicine, 2(2), 80-84. https://doi.org/10.70058/cjm.1580454
AMA
1.Taşkıran D, Kolsuz S. A Review of the Effect of Progesterone Use on Miscarriage in Early Pregnancy Bleeding. Cerasus J Med. 2025;2(2):80-84. doi:10.70058/cjm.1580454
Chicago
Taşkıran, Deniz, and Salih Kolsuz. 2025. “A Review of the Effect of Progesterone Use on Miscarriage in Early Pregnancy Bleeding”. Cerasus Journal of Medicine 2 (2): 80-84. https://doi.org/10.70058/cjm.1580454.
EndNote
Taşkıran D, Kolsuz S (June 1, 2025) A Review of the Effect of Progesterone Use on Miscarriage in Early Pregnancy Bleeding. Cerasus Journal of Medicine 2 2 80–84.
IEEE
[1]D. Taşkıran and S. Kolsuz, “A Review of the Effect of Progesterone Use on Miscarriage in Early Pregnancy Bleeding”, Cerasus J Med, vol. 2, no. 2, pp. 80–84, June 2025, doi: 10.70058/cjm.1580454.
ISNAD
Taşkıran, Deniz - Kolsuz, Salih. “A Review of the Effect of Progesterone Use on Miscarriage in Early Pregnancy Bleeding”. Cerasus Journal of Medicine 2/2 (June 1, 2025): 80-84. https://doi.org/10.70058/cjm.1580454.
JAMA
1.Taşkıran D, Kolsuz S. A Review of the Effect of Progesterone Use on Miscarriage in Early Pregnancy Bleeding. Cerasus J Med. 2025;2:80–84.
MLA
Taşkıran, Deniz, and Salih Kolsuz. “A Review of the Effect of Progesterone Use on Miscarriage in Early Pregnancy Bleeding”. Cerasus Journal of Medicine, vol. 2, no. 2, June 2025, pp. 80-84, doi:10.70058/cjm.1580454.
Vancouver
1.Deniz Taşkıran, Salih Kolsuz. A Review of the Effect of Progesterone Use on Miscarriage in Early Pregnancy Bleeding. Cerasus J Med. 2025 Jun. 1;2(2):80-4. doi:10.70058/cjm.1580454

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