Management of a Maxillary Defect Caused by Medication-Related Osteonecrosis of the Jaw with a Two-Piece Obturator: A Four-Year Case Report
Abstract
This case report describes the prosthetic rehabilitation of a maxillary defect resulting from medication-related osteonecrosis of the jaw (MRONJ) using a two-piece obturator-prosthesis system. A 75-year-old male patient with a history of prostate cancer and long-term antiresorptive therapy developed an oroantral communication following surgical resection of necrotic bone. Given the extent of the defect and the patient’s functional limitations, a two-piece obturator was designed, integrating a silicone-based soft liner for defect closure and a removable partial denture with a metal framework for retention. The prosthesis incorporated precision attachments on natural teeth and locator abutments on pre-existing implants to optimize stability and function. Follow-up assessments demonstrated significant improvements in phonetics, mastication, and overall patient satisfaction. A four-year follow-up confirmed the longterm success of this approach, emphasizing the advantages of a two-piece obturator over conventional single-unit designs. This case highlights the importance of individualized prosthetic planning for patients with MRONJ-related maxillary defects, offering a functional and durable solution to enhance quality of life.
Keywords
References
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Details
Primary Language
English
Subjects
Prosthodontics
Journal Section
Case Report
Publication Date
December 12, 2025
Submission Date
March 18, 2025
Acceptance Date
May 12, 2025
Published in Issue
Year 2025 Volume: 49 Number: 3
APA
Karayel, A. B., & Ersu, B. (2025). Management of a Maxillary Defect Caused by Medication-Related Osteonecrosis of the Jaw with a Two-Piece Obturator: A Four-Year Case Report. Clinical Dentistry and Research, 49(3), 172-177. https://doi.org/10.65022/clindentres.1660664
AMA
1.Karayel AB, Ersu B. Management of a Maxillary Defect Caused by Medication-Related Osteonecrosis of the Jaw with a Two-Piece Obturator: A Four-Year Case Report. Clin Dent Res. 2025;49(3):172-177. doi:10.65022/clindentres.1660664
Chicago
Karayel, Aslı Bengisu, and Bahadır Ersu. 2025. “Management of a Maxillary Defect Caused by Medication-Related Osteonecrosis of the Jaw With a Two-Piece Obturator: A Four-Year Case Report”. Clinical Dentistry and Research 49 (3): 172-77. https://doi.org/10.65022/clindentres.1660664.
EndNote
Karayel AB, Ersu B (December 1, 2025) Management of a Maxillary Defect Caused by Medication-Related Osteonecrosis of the Jaw with a Two-Piece Obturator: A Four-Year Case Report. Clinical Dentistry and Research 49 3 172–177.
IEEE
[1]A. B. Karayel and B. Ersu, “Management of a Maxillary Defect Caused by Medication-Related Osteonecrosis of the Jaw with a Two-Piece Obturator: A Four-Year Case Report”, Clin Dent Res, vol. 49, no. 3, pp. 172–177, Dec. 2025, doi: 10.65022/clindentres.1660664.
ISNAD
Karayel, Aslı Bengisu - Ersu, Bahadır. “Management of a Maxillary Defect Caused by Medication-Related Osteonecrosis of the Jaw With a Two-Piece Obturator: A Four-Year Case Report”. Clinical Dentistry and Research 49/3 (December 1, 2025): 172-177. https://doi.org/10.65022/clindentres.1660664.
JAMA
1.Karayel AB, Ersu B. Management of a Maxillary Defect Caused by Medication-Related Osteonecrosis of the Jaw with a Two-Piece Obturator: A Four-Year Case Report. Clin Dent Res. 2025;49:172–177.
MLA
Karayel, Aslı Bengisu, and Bahadır Ersu. “Management of a Maxillary Defect Caused by Medication-Related Osteonecrosis of the Jaw With a Two-Piece Obturator: A Four-Year Case Report”. Clinical Dentistry and Research, vol. 49, no. 3, Dec. 2025, pp. 172-7, doi:10.65022/clindentres.1660664.
Vancouver
1.Aslı Bengisu Karayel, Bahadır Ersu. Management of a Maxillary Defect Caused by Medication-Related Osteonecrosis of the Jaw with a Two-Piece Obturator: A Four-Year Case Report. Clin Dent Res. 2025 Dec. 1;49(3):172-7. doi:10.65022/clindentres.1660664