Clinical Research

EVALUATION OF NASOALVEOLAR MOLDING THERAPY ON MAXILLARY ARCH FORM IN INFANTS WITH UNILATERAL CLEFT LIP AND PALATE WITH DIGITAL MODELING

Volume: 49 Number: 3 December 12, 2025

EVALUATION OF NASOALVEOLAR MOLDING THERAPY ON MAXILLARY ARCH FORM IN INFANTS WITH UNILATERAL CLEFT LIP AND PALATE WITH DIGITAL MODELING

Abstract

Background and Aim: Nasoalveolar molding (NAM) is considered a routine part of pre-surgical orthopedic treatment protocols for patients with cleft lip and/or palate (CLP). Treating this deformity from birth to adulthood requires a multidisciplinary approach to achieve optimal aesthetics and function. This study aims to evaluate the effects of NAM therapy on the cleft segments in infants with unilateral CLP using digital modeling. Materials and Methods: The study included 30 patients with unilateral CLP, who completed NAM treatment and had pre- and post-treatment maxillary plaster models. These models were scanned with a model scanner to create digital models. Linear and angular measurements were made on the digital models to determine changes in the cleft width and the positions of the segments. Results: There was a significant decrease in the cleft width with NAM treatment (p<0.05). A significant decrease in intercanine distance was observed (p<0.05), while the intertuber distance was increased. A significant difference was found in the medial rotation of the larger segment before and after NAM (p<0.05), while no significant difference was observed in the lesser segment (p>0.05). In maxillary depth measurements, a significant decrease was observed in the larger segment (p<0.05), whereas no significant difference was found in the lesser segment (p>0.05). Conclusions: Pre-surgical NAM therapy contributes to the approximation of the cleft segments, facilitates the medial rotation of the larger segment towards the midline, and thus, helps achieve a more uniform arch form.

Keywords

References

  1. 1. Owens J, Jones J, Harris F. Epidemiology of facial clefting. Arch Dis Child 1985; 60: 521-524.
  2. 2. Jiang R, Bush JO, Lidral AC. Development of the upper lip: morphogenetic and molecular mechanisms. Dev Dyn: an official publication of the Am Assoc Anatomists 2006; 235: 1152-1166.
  3. 3. Dixon MJ, Marazita ML, Beaty TH, Murray JC. Cleft lip and palate: understanding genetic and environmental influences. Nat Rev Genet 2011; 12: 167-178.
  4. 4. Babai A, Irving M. Orofacial clefts: genetics of cleft lip and palate. Genes 2023; 14: 1603.
  5. 5. Salari N, Darvishi N, Heydari M, Bokaee S, Darvishi F, Mohammadi M. Global prevalence of cleft palate, cleft lip and cleft palate and lip: A comprehensive systematic review and meta-analysis. J Stomatol Oral Maxillofac Surg 2022; 123: 110-120.
  6. 6. Yılmaz HN, Özbilen EÖ, Üstün T. The prevalence of cleft lip and palate patients: a single-center experience for 17 years. Turk J Orthod 2019; 32: 139.
  7. 7. Grayson BH, Santiago PE, Brecht LE, Cutting CB. Presurgical nasoalveolar molding in infants with cleft lip and palate. Cleft Palate Craniofac J 1999; 36: 486-498.
  8. 8. Mishima K, Sugahara T, Mori Y, Sakuda M. Three-dimensional comparison between the palatal forms in infants with complete unilateral cleft lip, alveolus, and palate (UCLP) with and without Hotz’s plate. Cleft Palate Craniofac J 1996; 33: 77-83.

Details

Primary Language

English

Subjects

Orthodontics and Dentofacial Orthopaedics

Journal Section

Clinical Research

Publication Date

December 12, 2025

Submission Date

June 10, 2025

Acceptance Date

September 2, 2025

Published in Issue

Year 2025 Volume: 49 Number: 3

APA
Öz, A. Z., Can, İ., & Sönmaz Cural, F. (2025). EVALUATION OF NASOALVEOLAR MOLDING THERAPY ON MAXILLARY ARCH FORM IN INFANTS WITH UNILATERAL CLEFT LIP AND PALATE WITH DIGITAL MODELING. Clinical Dentistry and Research, 49(3), 143-149. https://doi.org/10.65022/clindentres.1716782
AMA
1.Öz AZ, Can İ, Sönmaz Cural F. EVALUATION OF NASOALVEOLAR MOLDING THERAPY ON MAXILLARY ARCH FORM IN INFANTS WITH UNILATERAL CLEFT LIP AND PALATE WITH DIGITAL MODELING. Clin Dent Res. 2025;49(3):143-149. doi:10.65022/clindentres.1716782
Chicago
Öz, Aslıhan Zeynep, İlknur Can, and Fatmanur Sönmaz Cural. 2025. “EVALUATION OF NASOALVEOLAR MOLDING THERAPY ON MAXILLARY ARCH FORM IN INFANTS WITH UNILATERAL CLEFT LIP AND PALATE WITH DIGITAL MODELING”. Clinical Dentistry and Research 49 (3): 143-49. https://doi.org/10.65022/clindentres.1716782.
EndNote
Öz AZ, Can İ, Sönmaz Cural F (December 1, 2025) EVALUATION OF NASOALVEOLAR MOLDING THERAPY ON MAXILLARY ARCH FORM IN INFANTS WITH UNILATERAL CLEFT LIP AND PALATE WITH DIGITAL MODELING. Clinical Dentistry and Research 49 3 143–149.
IEEE
[1]A. Z. Öz, İ. Can, and F. Sönmaz Cural, “EVALUATION OF NASOALVEOLAR MOLDING THERAPY ON MAXILLARY ARCH FORM IN INFANTS WITH UNILATERAL CLEFT LIP AND PALATE WITH DIGITAL MODELING”, Clin Dent Res, vol. 49, no. 3, pp. 143–149, Dec. 2025, doi: 10.65022/clindentres.1716782.
ISNAD
Öz, Aslıhan Zeynep - Can, İlknur - Sönmaz Cural, Fatmanur. “EVALUATION OF NASOALVEOLAR MOLDING THERAPY ON MAXILLARY ARCH FORM IN INFANTS WITH UNILATERAL CLEFT LIP AND PALATE WITH DIGITAL MODELING”. Clinical Dentistry and Research 49/3 (December 1, 2025): 143-149. https://doi.org/10.65022/clindentres.1716782.
JAMA
1.Öz AZ, Can İ, Sönmaz Cural F. EVALUATION OF NASOALVEOLAR MOLDING THERAPY ON MAXILLARY ARCH FORM IN INFANTS WITH UNILATERAL CLEFT LIP AND PALATE WITH DIGITAL MODELING. Clin Dent Res. 2025;49:143–149.
MLA
Öz, Aslıhan Zeynep, et al. “EVALUATION OF NASOALVEOLAR MOLDING THERAPY ON MAXILLARY ARCH FORM IN INFANTS WITH UNILATERAL CLEFT LIP AND PALATE WITH DIGITAL MODELING”. Clinical Dentistry and Research, vol. 49, no. 3, Dec. 2025, pp. 143-9, doi:10.65022/clindentres.1716782.
Vancouver
1.Aslıhan Zeynep Öz, İlknur Can, Fatmanur Sönmaz Cural. EVALUATION OF NASOALVEOLAR MOLDING THERAPY ON MAXILLARY ARCH FORM IN INFANTS WITH UNILATERAL CLEFT LIP AND PALATE WITH DIGITAL MODELING. Clin Dent Res. 2025 Dec. 1;49(3):143-9. doi:10.65022/clindentres.1716782