Can oral mucositis be prevented in patients receiving chemotherapy?

Yıl 2012, Cilt: 2 Sayı: 4, 155 - 163, 30.01.2014

Nida Ünal Çubukçu Sezgi Çınar

Öz

Objective: The aim of this study was to determine the effects of using sodium bicarbonate solution, benzydamine hydrochloride solution and black mulberry syrup for oral care on oral mucositis in patients receiving chemotherapy. 

Method: The data of the present experimental study were obtained by the researcher using “Patient Observation Form”, “Oral Mucosa Evaluation Form”, and “Visual Analog Scale”. Ninety patients included in the study were divided into three groups. Group 1, Group 2 and Group 3 used oral care solutions of benzydamine hydrochloride, sodium bicarbonate, and black mulberry syrup, respectively. Frequency and average±standard deviation, chi-square, Fisher chi-square, Kolmogorov Smirnov, t-test, ANOVA variance analysis and Bonferroni multiple comparison tests were used for evaluation of the data. 

Results: Sociodemographic characteristics and smoking habits showed no significant difference. On the second interview, the number of patients without mucositis in group 3 was higher than that of the other groups. Throat pain points in Group 1 and Group 2 were increased whereas in Group 3 no change was monitored. Moreover, in Group 1, higher oral dryness points were marked. According to the Rotterdam symptom list, activity level of Group 1 was better than that of the other groups on the first interview, and physical disturbance of Group 2 was much more than that of the other groups on the second interview. 

Conclusion: Black mulberry syrup usage for avoiding oral mucositis, oral mucosal pain and oral dryness is recommended in patients receiving chemotherapy treatment.

Key words: Oral care, black mulberry syrup, chemotherapy, oral mucositis, sodium bicarbonate

Anahtar Kelimeler

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Kemoterapi alan kanserli hastalarda oral mukozitler önlenebilir mi?

Öz

Amaç: Bu çalışmanın amacı, kemoterapi alan hastalarda ağız bakımı için sodyum bikarbonat solüsyonu, benzidamin hidroklorür solüsyonu ve karadut şurubu kullanımının oral mukozitlere etkisini belirlemektir. 

Yöntem: Araştırmanın verileri araştırmacı tarafından “Hasta İzlem Formu”, “Ağız Mukozası Değerlendirme Formu” ve “Ağrı Algı Skalası” kullanılarak toplandı. Araştırmanın örneklemini oluşturan 90 hasta üç gruba ayrıldı. Ağız bakım solüsyonu olarak Grup 1 “benzidamin hidroklorür”, Grup 2 “sodyum bikarbonat”, Grup 3 “karadut şurubu” kullandı. Verilerin değerlendirilmesinde frekans ve ortalama±standart sapma, ki-kare, Fisher ki-kare, Kolmogorov Smirnov, ANOVA, t-testi ve Bonferroni çoklu kıyaslama testleri kullanıldı. 

Bulgular: Üç grup arasında sosyodemografik özellikler ve sigara içme durumları açısından anlamlı fark bulunmadı. İkinci görüşmede; diğer gruplara göre Grup 3’de mukozit gelişmeyen hasta sayısı daha fazla oldu. Grup 1 ve Grup 2’de boğaz ağrısı sorunlarının arttığı, Grup 3’de değişiklik olmadığı, Grup 1’de ağız kuruluğu sorununun daha fazla olduğu belirlendi. Rotterdam semptom listesine göre; birinci görüşmede Grup 1’de aktivite düzeylerinin daha iyi olduğu, ikinci görüşmede ise Grup 2’de daha fazla fiziksel rahatsızlık yaşandığı belirlendi.

Sonuç: Kemoterapi alan hastalarda oral mukozitleri, ağız içi ağrıyı ve ağız kuruluğunu önlemek için karadut şurubu kullanılabilir.

Anahtar Kelimeler : Ağız bakımı, karadut şurubu, kemoterapi, oral mukozit, sodyum bikarbonat

Anahtar Kelimeler

Ağız bakımı, karadut şurubu, kemoterapi, oral mukozit, sodyum bikarbonat

Kaynakça

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