Regional dispersion of non-syndromic cleft lip with/without palate Turkish children patients and possible geographical effects

Yıl 2012, Cilt: 2 Sayı: 4, 164 - 168, 30.01.2014

Korkut Ulucan Arzu Akçay Burak Ersoy Deniz Kiraç Teoman Akçay Deniz Ergeç Ahmet İlter Güney

Öz

Objective: Non-syndromic cleft lip with/without palate (NSCL/P) takes part in multifactorial anomalies. In the present retrospective-descriptive study, we aimed to evaluate the distribution of Turkish children patients with non-syndromic cleft lip with/ without palate according to the geographic regions and analyse the possible geographic and environmental effects which can be considered in the aetiology of the anomaly. 

Method: Information about the origin, nutritional habits including vitamin intake, occupational and lifetime status were obtained from mothers of NSCL/P patients who gave birth between July 2006 and June 2010. 

Results: When regional status was investigated, it was found that the eastern parts of Turkey have a relatively higher number of NSCL/P patients than other regions. The ratio of the affected boys to affected girls was found as 154/136. Also, the average age of the mothers at the time of delivery was found to be 24.7. None of the mothers used alcohol or smoked during their lives.

Conclusions: Regional differences in nutritional habits and life style have various effects on NSCL/P occurrence, nevertheless more detailed studies are needed to specify the major differences that are responsible.

Key words: Cleft lip, cleft palate, nutritional habits, life style, geographical dispersion

Anahtar Kelimeler

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İzole dudak-damak yarıklı Türk çocuk hastaların bölgesel dağılımı ve olası bölgesel etkiler

Öz

Amaç: İzole dudak-damak yarıkları multifaktöriyel anomaliler arasında yer almaktadır. Bu retrospektif-tanımlayıcı çalışmada izole dudak-damak yarıklı Türk çocuk hastaların Türkiye’deki bölgesel dağılımlarını inceleyerek bölgesel ve yaşam tarzlarının, anomalinin oluşmasındaki olası etkilerini saptamayı amaçladık. 

Yöntem: Temmuz 2006-Haziran 2010 yılları arasında doğum yapan yarık dudak- damaklı çocukların annelerinden; kökenleri, vitamin alımı dahil beslenme alışkanlıkları, iş ve yaşam biçimleri hakkında bilgi toplanmıştır. 

Bulgular: Bölgesel olarak incelendiğinde Türkiye’nin doğu bölgelerinde izole dudak- damak yarık vakalarının diğer bölgelere göre daha yüksek sayıda olduğu tespit edilmiştir. Etkilenen erkek çocukların kız çocuklara oranının 154/136 olduğu saptanmıştır. Annelerin doğum anlarındaki ortalama yaşının ise 24,7 olduğu belirlenmiştir. Çalışmamıza katılan anneler hayatları boyunca alkol veya sigara kullanmamıştır.

Sonuç: Beslenme alışkanlıkları ve yaşam standartları bölgesel olarak değişmektedir ve bu değişimlerin izole dudak-damak yarık oluşumu üzerine etkileri vardır. Ancak sorumlu farklılıkların saptanabilmesi için daha detaylı çalışmalara ihtiyaç duyulmaktadır.

Anahtar Kelimeler : Dudak-damak yarıkları, beslenme alışkanlıkları, yaşam şekli, bölgesel dağılım

Anahtar Kelimeler

Dudak-damak yarıkları, beslenme alışkanlıkları, yaşam şekli, bölgesel dağılım

Kaynakça

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