Localizing Epileptic Focus with Interictal Scalp EEG in Patients with Focal Cortical Dysplasia

Yıl 2020, Cilt: 10 Sayı: 2, 163 - 165, 29.06.2020

Özgür Bilgin Topçuoğlu , İpek Midi

https://doi.org/10.33808/clinexphealthsci.598395

Öz

Objective: To assess the localizing value of interictal scalp EEG in epileptic focal cortical dysplasia (FCD) patients.

Methods: A retrospective observational study of EEG records of epileptic patients seen at the Marmara University Hospital was performed. EEG and MRI findings were evaluated to detect a possible correlation. 

Results: EEG findings were consistent with MRI findings in 6 patients (37.5%).

Conclusion: EEG findings were irrelevant in 62.5% (n:10) of patients. Additional imaging techniques such as ictal SPECT, MEG etc. will clearly augment the success of lesion localisation in FCD patients.

Anahtar Kelimeler

EEG, focal cortical dysplasia, interictal

Kaynakça

• Referans 1. Sullivan LR, Kull LL, Sweeney DB, Davis CP. Cortical dysplasia: zones of epileptogenesis. Am J Electroneurodiagnostic Technol. 2005; 45: 49-60.Referans 2. Taylor DC, Falconer MA, Bruton CJ, Corsellis JA. Focal dysplasia of the cerebral cortex in epilepsy. J Neurol Neurosurg Psychiatry 1971; 34: 369-387.Referans 3. Leach JL, Greiner HM, Miles L, Mangano FT. Imaging spectrum of cortical dysplasia in children. Semin. Roentgenol. 2014;49: 99-111.Referans 4. Tassi L, Colombo N, Garbelli R, Francione S, Lo Russo G, Mai R, Cardinale F, Cossu M, Ferrario A, Galli C, Bramerio M, Citterio A, Spreafico R. Focal cortical dysplasia: neurpathological subtypes, EEG, neuroimaging and surgical outcome. Brain 2002; 125: 1719-1732.Referans 5. Crino PB. Focal Cortical Dysplasia. Semin Neurol. 2015: 35: 201-208.Referans 6. Rosenow F, Luders H. Presurgical evaluation of epilepsy. Brain 2001; 124: 1683-1700.Referans 7. Krsek P, Pieper T, Karlmeier A, Hildebrandt M, Kolodziejczyk D, Winkler P, Pauli E, Blümcke I, Holthausen H. Different presurgical characteristics and seizure outcomes in children with focal cortical dysplasia type I or II. Epilepsia 2009; 50:125-137.Referans 8. Gambardella A, Palmini A, Andermann F, Dubeau F, Da Costa JC, Quesney LF, Andermann E, Olivier A. Usefulness of focal rythmic discharges on scalp EEG of patients with focal cortical dysplasia and intractable epilepsy. Electroencephalogr Clin Neurophysiol 1996; 98: 243-249.Referans 9. Gaitanis JN, Donahue J. Focal cortical dysplasia. Pediatric Neurology2013; 49: 79-87.Referans 10. Wyllie E, Comair YG, Kotagal P, Bulacio J, Bingaman W, Ruggieri P. Seizure outcome after epilepsy surgery in children and adolescents. Ann Neurol 1998; 44: 740-748.Referans 11. Hauptman JS, Mathern GW. Surgical treatment of epilepsy associated with cortical dysplasia: 2012 update. Epilepsia. 2012 ;53 :98-104.Referans 12. Noachtar S, Bilgin O, Rémi J, Chang N, Midi I, Vollmar C, Feddersen B. Interictal regional polyspikes in noninvasive EEG suggest cortical dysplasia as etiology of focal epilepsies. Epilepsia. 2009 ; 50: 550-555.Referans 13. Lerner JT, Salamon N, Hauptman JS, Velasco TR, Hemb M, Wu JY, Sankar R, Donald Shields W, Engel J Jr, Fried I, Cepeda C, Andre VM, Levine MS, Miyata H, Yong WH, Vinters HV, Mathern GW.Assessment and surgical outcomes for mild type I and severe type II cortical dysplasia: a critical review and the UCLA experience. Epilepsia. 2009 ;50: 1310-1335.