Effect of Pruritus on Sleep Quality in Individuals Undergoing Hemodialysis Effect of Pruritus on Sleep Quality

Yıl 2022, Cilt: 12 Sayı: 2, 541 - 547, 30.06.2022

Nesligül Aybek Fatma Özkan Tuncay

https://doi.org/10.33808/clinexphealthsci.1008971

Öz

Introduction: Although uremic pruritus is not a life-threatening problem itself, it affects the quality of life and daily life activities of the patients and negatively changes the patient's adaption to the disease.
Methods: This descriptive and analytical study was conducted with 219 patients who underwent hemodialysis in State Hospital, University Hospital hemodialysis units and a private dialysis center and met the study criteria. Research data were collected using the Introductory Information Form, 5-D Pruritus Scale and Pittsburg Sleep Quality Index. In the analysis of the data, t test, One - Way ANOVA test, Mann-Whitney U test, Kruskal-Wallis T test, Perason correlation analysis and Dunnet T3 Post Hoc test were used.
Results: In the study, the 5-D Pruritus Scale mean score of the patients was 12.70±3.35 points, and the Pittsburg Sleep Quality Index score was 12.82±2.42. A positive, moderately significant (r=.509, p<0.05) relationship was found between the mean scores of the two scales. It was determined that patients with unbearable itching, who defined itching prognosis as bad, stated that itching affected their daily activities and experienced widespread itching had worse sleep quality (p<0.05).
Conclusion: Patients undergoing hemodialysis experience moderate itching and their sleep quality is generally poor. However, there is a moderate relationship between itching and sleep quality.

Anahtar Kelimeler

Hemodialysis, Pruritus, Sleep Quality

Kaynakça

• [1] Akyol A, Yurdusever S, Temizkan A, Sifil H, Ecder T. Hemodiyaliz hastalarının uyku sorunlarına etki eden faktörlerin incelenmesi. Nefroloji Hemşireliği Dergisi 2017; 2(12):49-57. (Turkish)
• [2] Topbaş E, Bingöl G. Psikososyal boyutu ile diyaliz tedavisi ve uyum sürecine yönelik hemşirelik girişimleri. Nefroloji Hemşireliği Dergisi 2017; 1(12):36-42. (Turkish)
• [3] Kavurmacı M, Tan M. Üremik kaşıntı ve hemşirelik bakımı. Anadolu Hemşirelik ve Sağlık Bilimleri Dergisi 2014; 18(1):57- 62. (Turkish)
• [4] Olıveıra M, Pıgarı VG, Ogata M, Mıot HA, Ponce D, Abbade L. Gabapentin versus dexchlorpheniramine as treatment for uremic pruritus:a randomised controlled trial. Eur J Dermatol 2018; 28(4):488-495.
• [5] Mettang T, Kremer EA. Uremic pruritus. Kidney Int. 2015; 87(4):685-691.
• [6] Min J, Kim S, Kim Y, Jin D, Song H, Choi E, Kim Y, Kim Y, Kang S, Kim N, Yang C, Kim Y. Comparison of uremic pruritus between patients undergoing hemodialysis and peritoneal dialysis. Kidney Res and Clin Pract. 2016; 35:107-113.
• [7] Du T, Barhen A, Bhatia JS, Wolpowitz D. Loss of papillary dermal calcitonin gene related peptide – expressing neurons significantl correlates with uremic pruritus. J Invest Dermatol. 2016; 136(11):2323-2325.
• [8] Hindistan S, Deniz A. Hemodiyaliz tedavisi alan hastalarda semptom değerlendirmesi. Bezmialem Science 2018; 6:112- 118. (Turkish)
• [9] Simonsen E, Komenda P, Lemer B, Askin N, Bohm C, Shaw J, Tangri N, Rigatto C. Treatment of uremic pruritus:a systematic review. Am J Kidney Dis 2017; 70(5):638-655.
• [10] Ersoy NA, Akyar İ. Kronik böbrek yetmezliği olan hastalarda 5-D kaşıntı ölçeğinin geçerlilik güvenirlik çalışması. Acıbadem Univ. Sağlık Bilim. Derg 2017; 9(4):455-461. (Turkish)
• [11] Pereira M, Stander S. Assenssment of severity and burden of pruritus. Allergol Int. 2017; 66:3-7.
• [12] Velioğlu P. Hemşirelikte Kavram ve Kuramlar. 2. Baskı. İstanbul: Akademi Basın; 2012. s.528. (Turkish)
• [13] Inui S. Nalfurafine hydrochloride to treat pruritus: a review. Clin Cosmet Investig Dermatol. 2015; 8:249-255.
• [14] Rehman IU, Chia D, Ahmed R, Khan N, Rahman A, Munib S, Lee L, Chan K, Khan T. A randomized controlled trial for effectiveness of zolpidem versus acupressure on sleep in hemodialysis patients having chronic kidney disease – associated pruritus. Medicine 2018; 97(31):1-6.
• [15] Jin D, Shen H, Feng S, Zhan Z, Jiang L, Qiu B, Zeng Y, Shi Y. Treatment effects of different ıncident dialysis modalities on pruritus in elderly uremic patients. Int J Gerontol. 2014; 8:223- 227.
• [16] Elman S, Hynan LS, Gabriel V, Mayo MJ. The 5-D itch scale: a new measure of pruritus. Br J Dermatol 2010; 162(3):587-593.
• [17] Buysse DJ, Reynolds CF, Monk TH. The Pittsburgh sleep quality ındex: a new instrument for psychiatric practice and research. Psychiatry Res. 1989; 28(2):193-213.
• [18] Ağargün MY, Kara H, Anlar O. Pittsburg uyku kalitesi indeksinin geçerliği ve güvenirliği. Türk Psikiyatri Derg. 1996; 7:107-111. (Turkish)
• [19] Güder S, Karaca Ş, Kulaç M, Yüksel Ş, Güder H. Afyonkarahisar ve çevresinde diyalize giren kronik böbrek yetmezlikli hastalarda deri bulguları. Türkderm 2012; 46:181-185. (Turkish)
• [20] Ko MJ, Peng Y, Chen H, Hsu SP, Pai MP, Yang JY, Wen SY, Jee SH, Wu HY, Chiu HC. Interleukin-31 is associated with uremic pruritus in patients receiving hemodialysis. J Am Acad Dermatol. 2014; 71(6):1151-1159.
• [21] Küçükünal A, Altunay İA, Salman KE, Atış G. Hemodiyaliz hastalarında üremik pruritis ve yaşam kalitesi ilişkisi. Türkderm 2015; 49(1):23-27. (Turkish)
• [22] Sukul N, Wang M, Bieber B, Li Y, Lopes AA, Speyer E, Stengel B. Prurıtıs ın chronıc kıdney dısease patıents: early results from CKDOPPS. Nephrol Dial Transplant. 2016; 31(1):187.
• [23] Akhyani M, Ganji MR, Samadi N, Khamesan B, Daneshpazhooh M. Pruritus in hemodialysis patients. BMC Dermotol. 2005; 5(7):1-6.
• [24] Shavit L, Grenader T, Lifschitz M, Slotki I. Use of pregabalin in the management of chronic uremic pruritus. J Pain Symptom Manage. 2012; 45(4):776-781.
• [25] Taskapan H, Ates F, Kaya B, Emul M, Kaya M, Taskapan Ç, Şahin İ. Psychiatric disorders and large interdialytic weight gain in patients on chronic haemodialysis. Nephrology 2005; 10(1):15-20.
• [26] Indrarini A, Zahra AN, Yona S. The relationship between anemia, depression, duration of hemodialysis and quality of sleep among end-stage renal disease patients. Enferm Clin. 2019; 29(2):24-29.
• [27] Shen Q, He Q. Sleep quality, anxiety and quality of life in stable hemodialysis patients. Hong Kong J Nephrol 2015; 17(2):129.
• [28] Sert F, Demir AB, Bora İ, Yıldız A, Ocakoğlu G, Ersoy A. Kronik renal yetmezlikli ve böbrek nakilli hastalarda uyku bozukluğunun araştırılması ve bunun yaşam kalitesi üzerine etkisi, J Turk Sleep Med. 2015; 1:15-19. (Turkish)
• [29] Pierratos A, Hanly PJ. Sleep disorders over the full range of chronic kidney disease. Blood Purif 2011;31:146-150
• [30] Elder SJ, Pisoni RL, Akizowa T, Fissell R, Andrucci V, Fukuhara S, Kurokawa K, Rayner H, Furniss A, Port F, Saran R. Sleep quality predicts quality of life and mortality risk in haemodialysis patients: results from the dialysis outcomes and practice patterns study. Nephrol Dial Transplant 2008; 23:998-1004.
• [31] Ricardo A, Vivien G, Chen J, Couvert E, Kapella M, Prased B, Parvathaneni S, Knutson K, Lash J. Association of sleep duration, symptoms and disorders with mortality in adults with chronic kidney disease. Kidney Int Rep 2017; 2:866-873.
• [32] Karadağ E, Kılıç SP, Karatay G. Effect of baby oil on pruritus, sleep quality and quality of life in hemodialysis patients: pretest-post-test modeş with control groups. Jpn J Nurs Sci. 2014; 11:180-189