Research Article
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Year 2025, Volume: 15 Issue: 3, 602 - 611, 30.09.2025
https://doi.org/10.33808/clinexphealthsci.1637133

Abstract

References

  • Salanitri S, Seow WK. Developmental enamel defects in the primary dentition: aetiology and clinical management. Aust Dent J. 2013;58(2):133-266. https://doi.org/10.1111/adj.12039
  • Seow WK. Developmental defects of enamel and dentine: challenges for basic science research and clinical management. Aust Dent J. 2014;59 Suppl 1:143-154. https://doi.org/10.1111/adj.12104
  • Alaluusua S, Lukinmaa PL, Vartiainen T, Partanen M, Torppa J, Tuomisto J. Polychlorinated dibenzo-p-dioxins and dibenzofurans via mother's milk may cause developmental defects in the child's teeth. Environ Toxicol Pharmacol. 1996;1(3):193-197. https://doi.org/10.1016/1382-6689(96)00007-5
  • Jälevik B, Norén JG. Enamel hypomineralisation of permanent first molars: a morphological study and survey of possible aetiological factors. Int J Paediatr Dent. 2000;10(4):278-289. https://doi.org/10.1046/j.1365-263x.2000.00210.x
  • Elfrink ME, Schuller AA, Weerheijm KL, Veerkamp JS. Hypomineralised second primary molars: prevalence data in Dutch 5-year-olds. Caries Res. 2008;42(4):282-285. https://doi.org/10.1159/000135674
  • Weerheijm KL. Molar incisor hypomineralisation (MIH). Eur J Paediatr Dent. 2003;4(3):114-120.
  • Mittal N, Sharma BB. Hypomineralised second primary molars: prevalence, defect characteristics and possible association with molar incisor hypomineralisation in Indian children. Eur Arch Paediatr Dent. 2015;16(6):441-447. https://doi.org/10.1007/s40368-015-0190-z
  • Borrego-Martí N, Peris-Corominas R, Maura-Solivellas I, Ferrés-Padró E, Ferrés-Amat E. Hypomineralisation of second primary molars and primary canines: prevalence and description of lesions in a population of 153 patients visited at a hospital paediatric dentistry service. Eur J Paediatr Dent. 2021;22(3):237–242. https://doi.org/10.23804/ejpd.2021.22.03.11
  • Halal F, Raslan N. Prevalence of hypomineralised second primary molars (HSPM) in Syrian preschool children. Eur Arch Paediatr Dent. 2020;21(6):711–717. https://doi.org/10.1007/s40368-020-00520-2
  • McCarra C, Olegário IC, O’Connell AC, Leith R. Prevalence of hypomineralised second primary molars (HSPM): A systematic review and meta-analysis. Int J Paediatr Dent. 2022;32: 367–382. https://doi.org/10.1111/ipd.12892
  • Lygidakis NA, Wong F, Jälevik B, Vierrou AM, Alaluusua S, Espelid I. Best clinical practice guidance for clinicians dealing with children presenting with molar-incisor-hypomineralisation (MIH): an EAPD policy document. Eur Arch Paediatr Dent. 2010;11(2):75–81. https://doi.org/10.1007/BF03262716
  • Jälevik B, Klingberg GA. Dental treatment, dental fear and behaviour management problems in children with severe enamel hypomineralization of their permanent first molars. Int J Paediatr Dent. 2002;12(1):24–32.
  • Elfrink ME, ten Cate JM, Jadoe VW, Hofman A, Moll HA, Veerkamp JS. Deciduous molar hypomineralisation and molar incisor hypomineralisation. J Dent Res. 2012;91(6):551-555. https://doi.org/10.1177/0022034512440450
  • Garot E, Denis A, Delbos Y, Manton D, Silva M, Rouas P. Are hypomineralised lesions on second primary molars (HSPM) a predictive sign of molar incisor hypomineralisation (MIH)? A systematic review and a meta-analysis. J Dent. 2018;72:8–13. https://doi.org/10.1016/j.jdent.2018.03.005
  • Lima LJS, Ramos-Jorge ML, Soares MEC (2021, December 1). Prenatal, perinatal and postnatal events associated with hypomineralized second primary molar: a systematic review with meta-analysis. Clin Oral Invest. 2021;25:6501–6516. https://doi.org/10.1007/s00784-021-04146-6
  • Akyildiz MB, Karaoğlu Y, Öztürk Ö, Taşpınar E, Sönmez I. Hypomineralised second primary molars: prevalence and etiology in Aydın. International Dental Journal. 2024;74(1):88. https://doi.org/10.1016/j.identj.2024.07.838.
  • Owen ML, Ghanim A, Elsby D, Manton DJ. Hypomineralized second primary molars: prevalence, defect characteristics and relationship with dental caries in Melbourne preschool children. Aust Dent J. 2018;63(1):72–80. https://doi.org/10.1111/adj.12567
  • Ghanim A, Elfrink M, Weerheijm K, Mariño R, Manton D. A practical method for use in epidemiological studies on enamel hypomineralisation. Eur Arch Paediatr Dent. 2015;16(3):235–246. https://doi.org/10.1007/s40368-015-0178-8
  • Urbaniak, G.C. and Plous, S. (2013) Research Randomizer (Version 4.0). Computer Software. http://www.randomizer.org/
  • Bekes K. Molar Incisor Hypomineralization A Clinical Guide to Diagnosis and Treatment. Springer; 2020.
  • Ghanim A, Silva MJ, Elfrink ME, Lygidakis NA, Mariño RJ, Weerheijm KL, Manton DJ. Molar incisor hypomineralisation (MIH) training manual for clinical field surveys and practice. Eur Arch Paediatr Dent. 2017;18(4):225-242. https://doi.org/10.1007/s40368-017-0293-9
  • Lima LRS, Pereira AS, de Moura MS, Lima CCB, Paiva SM, Moura L de FA de D, de Deus Moura de Lima M. Pre-term birth and asthma is associated with hypomineralized second primary molars in pre-schoolers: A population-based study. Int J Paediatr Dent. 2020;30(2): 193–201. https://doi.org/10.1111/ipd.12584
  • Garot E, Rouas P, Somani C, Taylor GD, Wong F, Lygidakis NA. An update of the aetiological factors involved in molar incisor hypomineralisation (MIH): a systematic review and meta-analysis. Eur Arch Paediatr Dent. 2022;23(1):23-38. https://doi.org/10.1007/s40368-021-00646-x
  • Robles MJ, Ruiz M, Bravo-Perez M, González E, Peñalver MA. Prevalence of enamel defects in primary and permanent teeth in a group of schoolchildren from Granada (Spain). Med Oral Patol Oral Cir Bucal. 2013;18(2):e187-e193. https://doi.org/10.4317/medoral.18580
  • Elfrink ME, Moll HA, Kiefte-de Jong JC, El Marroun H, Jaddoe VW, Hofman A, Stricker BH, ten Cate JM, Veerkamp JS. Is maternal use of medicines during pregnancy associated with deciduous molar hypomineralisation in the offspring? A prospective, population-based study. Drug Saf. 2013;36(8):627-633. https://doi.org/10.1007/s40264-013-0078-y
  • Avcı B, Kaptan A. Comparison of mobile application-based teledentistry method wıth face-to-face oral examination assessment. Contemp Pediatr Dent 2023:4(1):15-31.
  • Petersen PE, Baez RJ. Oral Health Surveys: Basic Methods, 5th ed. World Health Organization; 2013.
  • Monse B, Heinrich-Weltzien R, Benzian H, Holmgren C, Van Palenstein Helderman W. PUFA – An index of clinical consequences of untreated dental caries. Community Dentistry and Oral Epidemiology. 2010;38: 77–82. https://doi.org/10.1111/j.1600-0528.2009.00514.x
  • Karakaya E, Sonmez H. The relationship between hypomineralized second primary molars and molar ıncisor hypomineralization in a group of school-aged children in Turkey. European Journal of General Dentistry. 2021;10: 65–72. https://doi.org/10.1055/s-0041-1732951
  • Singh R, Srivastava B, Gupta N. Prevalence and pattern of hypomineralized second primary molars in children in Delhi–NCR. Int J Clin Pediatr Dent. 2020;13(5):501–503. https://doi.org/10.5005/jp-journals-10005-1828
  • Meer Z, Almalki AY. Prevalence of Hypomineralization in second primary molars (HSPM) in 7 to 10-year-old Saudi children. Journal of Research in Medical and Dental Science. 2020;8(5):124–127.
  • Oyedele TA, Folayan MO, Oziegbe EO. Hypomineralised second primary molars: prevalence, pattern and associated co morbidities in 8- to 10-year-old children in Ile-Ife, Nigeria. BMC Oral Health. 2016;16(1):65. https://doi.org/10.1186/s12903-016-0225-9
  • Ghanim A, Manton D, Marino˜ R, Morgan M, Bailey D. Prevalence of demarcated hypomineralisation defects in second primary molars in Iraqi children. Int J Paediatr Dent. 2013;23:48–55. https://doi.org/10.1111/j.1365-263X.2012.01223.x
  • Elfrink M, Ghanim A, Manton D, Weerheijm K. Standardised studies on molar incisor hypomineralisation (MIH) and hypomineralised second primary molars (HSPM): a need. Eur Arch Paediatr Dent. 2015;16(3):247–255. https://doi.org/10.1007/s40368-015-0179-7
  • Goyal A, Dhareula A, Gauba K, Bhatia SK. Prevalence, defect characteristics and distribution of other phenotypes in 3- to 6-year-old children affected with Hypomineralised Second Primary Molars. Eur Arch Paediatr Dent. 2019;20:585–593. https://doi.org/10.1007/s40368-019-00441-9
  • Sidhu N, Wang Y, Barrett E, Casas M. Prevalence and presentation patterns of enamel hypomineralisation (MIH and HSPM) among paediatric hospital dental patients in Toronto, Canada: a cross-sectional study. Eur Arch Paediatr Dent. 2020;21(2): 263–270. https://doi.org/10.1007/s40368-019-00477-x
  • William R. Proffit, Henry Fields, Brent Larson, David M. Sarver. Contemporary Orthodontics. Elsevier Health Sciences 6; 2018.
  • Velló MA, Martínez-Costa C, Catalá M, Fons J, Brines J, Guijarro-Martínez R. Prenatal and neonatal risk factors for the development of enamel defects in low birth weight children. Oral Dis. 2010;16: 257–262. https://doi.org/10.1111/j.1601-0825.2009.01629.x
  • Devi K P, Goyal A, Gauba K, Bharti B, Jaiswal M, Gupta A, Singh SK. Prenatal, perinatal and postnatal risk factors associated with hypomineralised second primary molars – A cross-sectional study. Pediatric Dental Journal. 2023;33:159–166. https://doi.org/10.1016/j.pdj.2023.06.002
  • Masumo R, Bårdsen A, Åstrøm AN. Developmental defects of enamel in primary teeth and association with early life course events: a study of 6–36 month old children in Manyara, Tanzania. BMC Oral Health. 2013;13:21. https://doi.org/10.1186/1472-6831-13-21
  • Gambetta-Tessini K, Mariño R, Ghanim A, Calache H, Manton DJ. Carious lesion severity and demarcated hypomineralized lesions of tooth enamel in schoolchildren from Melbourne, Australia. Aust Dent J. 2018;63:365–373. https://doi.org/10.1111/adj.12626
  • Gambetta-Tessini K, Mariño R, Ghanim A, Calache H, Manton DJ. The impact of MIH/HSPM on the carious lesion severity of schoolchildren from Talca. Chile. Eur Arch Paediatr Dent. 2019;20(5):417–423. https://doi.org/10.1007/s40368-019-00416-w
  • Ghanim AM, Morgan MV, Mariño RJ, Bailey DL, Manton DJ. Risk factors of hypomineralised second primary molars in a group of Iraqi schoolchildren. Eur Arch Paediatr Dent. 2012;13(3):111–118. https://doi.org/10.1007/BF03262856
  • Serna Muñoz C, Ortiz Ruiz AJ, Pérez Silva A, Bravo-González LA, Vicente A. Second primary molar hypomineralisation and drugs used during pregnancy and infancy. A systematic review. Clin Oral Investig. 2020;24:1287–1297. https://doi.org/10.1007/s00784-019-03007-7
  • Lopes-Fatturi A, Menezes JVNB, Fraiz FC, Assunção LR da S, de Souza JF. Systemic exposures associated with hypomineralized primary second molars. Pediatr Dent. 2019;15;41(5):364-370.
  • Silva MJ, Kilpatrick NM, Craig JM, Manton DJ, Leong P, Burgner D, Scurrah KJ. Etiology of hypomineralized second primary molars: A prospective twin study. J Dent Res. 2019;98(1):77–83. https://doi.org/10.1177/0022034518792870
  • Infant and young child feeding. [Accessed: 17 August 2024]. Available at: https://www.who.int/en/news-room/fact-sheets/detail/infant-and-young-child-feeding
  • Elfrink MEC, Moll HA, Kiefte-de Jong JC, Jaddoe VWV, Hofman A, Ten Cate JM, Veerkamp JSJ. Pre- and postnatal determinants of deciduous molar hypomineralisation in 6-year-old children. The Generation R Study. PLoS One. 2014;9(7):e91057. https://doi.org/10.1371/journal.pone.0091057
  • Koch MJ, Bührer R, Pioch T, Schärer K. Enamel hypoplasia of primary teeth in chronic renal failure. Pediatr Nephrol. 1999;13:68–72. https://doi.org/10.1007/s004670050566

Prevalence of Hypomineralized Second Primary Molars and Associated Factors in Preschool Children in Trabzon, Türkiye: A cross-sectional study

Year 2025, Volume: 15 Issue: 3, 602 - 611, 30.09.2025
https://doi.org/10.33808/clinexphealthsci.1637133

Abstract

Objective: To determine the prevalence of hypomineralized second primary molar (HSPM) along with its related factors in a sample group of Turkish preschool children.
Methods: A group of 513 Turkish preschool children (29-84 months) from Ortahisar district of Trabzon was selected randomly. Information regarding potential risk indicators was collected through a questionnaire containing questions about sociodemographic status, prenatal, perinatal and postnatal conditions. The HSPM was scored using the European Academy of Paediatric Dentistry (EAPD) criteria. Decayed, missing, and filled teeth (dmft) and P–Pulpal involvement, U-Ulceration, F-Fistula and A-abscess (pufa) index were evaluated. Descriptive analysis and multivariate logistic regression analysis were used for statistical evaluation. A p-value below 0.05 was considered as significant.
Results: The prevalence of HSPM was found to be 6.8% for children and 4.6% for teeth. The most common type of HSPM defect in teeth was white creamy demarcated opacities. In this study, a significant association was found between child age and HSPM (B= -1.074; p < .05). Among the postnatal factors, breastfeeding duration of more than 6 months (B= 1.307; p < .05); in the first year of life no lower respiratory tract infection (B= -0.866; p < .05), having a history of otitis (B= 1.105; p < .05), and renal disease were found to be factors associated with HSPM (B= 2.773; p < .05).
Conclusion: HSPM prevalence observed in this study is consistent with prior research, and its associations with early-life conditions—including renal disease, otitis, and extended breastfeeding—reinforce the etiological relevance of postnatal systemic stressors in enamel hypomineralization. These findings warrant further etiopathogenic investigations.

References

  • Salanitri S, Seow WK. Developmental enamel defects in the primary dentition: aetiology and clinical management. Aust Dent J. 2013;58(2):133-266. https://doi.org/10.1111/adj.12039
  • Seow WK. Developmental defects of enamel and dentine: challenges for basic science research and clinical management. Aust Dent J. 2014;59 Suppl 1:143-154. https://doi.org/10.1111/adj.12104
  • Alaluusua S, Lukinmaa PL, Vartiainen T, Partanen M, Torppa J, Tuomisto J. Polychlorinated dibenzo-p-dioxins and dibenzofurans via mother's milk may cause developmental defects in the child's teeth. Environ Toxicol Pharmacol. 1996;1(3):193-197. https://doi.org/10.1016/1382-6689(96)00007-5
  • Jälevik B, Norén JG. Enamel hypomineralisation of permanent first molars: a morphological study and survey of possible aetiological factors. Int J Paediatr Dent. 2000;10(4):278-289. https://doi.org/10.1046/j.1365-263x.2000.00210.x
  • Elfrink ME, Schuller AA, Weerheijm KL, Veerkamp JS. Hypomineralised second primary molars: prevalence data in Dutch 5-year-olds. Caries Res. 2008;42(4):282-285. https://doi.org/10.1159/000135674
  • Weerheijm KL. Molar incisor hypomineralisation (MIH). Eur J Paediatr Dent. 2003;4(3):114-120.
  • Mittal N, Sharma BB. Hypomineralised second primary molars: prevalence, defect characteristics and possible association with molar incisor hypomineralisation in Indian children. Eur Arch Paediatr Dent. 2015;16(6):441-447. https://doi.org/10.1007/s40368-015-0190-z
  • Borrego-Martí N, Peris-Corominas R, Maura-Solivellas I, Ferrés-Padró E, Ferrés-Amat E. Hypomineralisation of second primary molars and primary canines: prevalence and description of lesions in a population of 153 patients visited at a hospital paediatric dentistry service. Eur J Paediatr Dent. 2021;22(3):237–242. https://doi.org/10.23804/ejpd.2021.22.03.11
  • Halal F, Raslan N. Prevalence of hypomineralised second primary molars (HSPM) in Syrian preschool children. Eur Arch Paediatr Dent. 2020;21(6):711–717. https://doi.org/10.1007/s40368-020-00520-2
  • McCarra C, Olegário IC, O’Connell AC, Leith R. Prevalence of hypomineralised second primary molars (HSPM): A systematic review and meta-analysis. Int J Paediatr Dent. 2022;32: 367–382. https://doi.org/10.1111/ipd.12892
  • Lygidakis NA, Wong F, Jälevik B, Vierrou AM, Alaluusua S, Espelid I. Best clinical practice guidance for clinicians dealing with children presenting with molar-incisor-hypomineralisation (MIH): an EAPD policy document. Eur Arch Paediatr Dent. 2010;11(2):75–81. https://doi.org/10.1007/BF03262716
  • Jälevik B, Klingberg GA. Dental treatment, dental fear and behaviour management problems in children with severe enamel hypomineralization of their permanent first molars. Int J Paediatr Dent. 2002;12(1):24–32.
  • Elfrink ME, ten Cate JM, Jadoe VW, Hofman A, Moll HA, Veerkamp JS. Deciduous molar hypomineralisation and molar incisor hypomineralisation. J Dent Res. 2012;91(6):551-555. https://doi.org/10.1177/0022034512440450
  • Garot E, Denis A, Delbos Y, Manton D, Silva M, Rouas P. Are hypomineralised lesions on second primary molars (HSPM) a predictive sign of molar incisor hypomineralisation (MIH)? A systematic review and a meta-analysis. J Dent. 2018;72:8–13. https://doi.org/10.1016/j.jdent.2018.03.005
  • Lima LJS, Ramos-Jorge ML, Soares MEC (2021, December 1). Prenatal, perinatal and postnatal events associated with hypomineralized second primary molar: a systematic review with meta-analysis. Clin Oral Invest. 2021;25:6501–6516. https://doi.org/10.1007/s00784-021-04146-6
  • Akyildiz MB, Karaoğlu Y, Öztürk Ö, Taşpınar E, Sönmez I. Hypomineralised second primary molars: prevalence and etiology in Aydın. International Dental Journal. 2024;74(1):88. https://doi.org/10.1016/j.identj.2024.07.838.
  • Owen ML, Ghanim A, Elsby D, Manton DJ. Hypomineralized second primary molars: prevalence, defect characteristics and relationship with dental caries in Melbourne preschool children. Aust Dent J. 2018;63(1):72–80. https://doi.org/10.1111/adj.12567
  • Ghanim A, Elfrink M, Weerheijm K, Mariño R, Manton D. A practical method for use in epidemiological studies on enamel hypomineralisation. Eur Arch Paediatr Dent. 2015;16(3):235–246. https://doi.org/10.1007/s40368-015-0178-8
  • Urbaniak, G.C. and Plous, S. (2013) Research Randomizer (Version 4.0). Computer Software. http://www.randomizer.org/
  • Bekes K. Molar Incisor Hypomineralization A Clinical Guide to Diagnosis and Treatment. Springer; 2020.
  • Ghanim A, Silva MJ, Elfrink ME, Lygidakis NA, Mariño RJ, Weerheijm KL, Manton DJ. Molar incisor hypomineralisation (MIH) training manual for clinical field surveys and practice. Eur Arch Paediatr Dent. 2017;18(4):225-242. https://doi.org/10.1007/s40368-017-0293-9
  • Lima LRS, Pereira AS, de Moura MS, Lima CCB, Paiva SM, Moura L de FA de D, de Deus Moura de Lima M. Pre-term birth and asthma is associated with hypomineralized second primary molars in pre-schoolers: A population-based study. Int J Paediatr Dent. 2020;30(2): 193–201. https://doi.org/10.1111/ipd.12584
  • Garot E, Rouas P, Somani C, Taylor GD, Wong F, Lygidakis NA. An update of the aetiological factors involved in molar incisor hypomineralisation (MIH): a systematic review and meta-analysis. Eur Arch Paediatr Dent. 2022;23(1):23-38. https://doi.org/10.1007/s40368-021-00646-x
  • Robles MJ, Ruiz M, Bravo-Perez M, González E, Peñalver MA. Prevalence of enamel defects in primary and permanent teeth in a group of schoolchildren from Granada (Spain). Med Oral Patol Oral Cir Bucal. 2013;18(2):e187-e193. https://doi.org/10.4317/medoral.18580
  • Elfrink ME, Moll HA, Kiefte-de Jong JC, El Marroun H, Jaddoe VW, Hofman A, Stricker BH, ten Cate JM, Veerkamp JS. Is maternal use of medicines during pregnancy associated with deciduous molar hypomineralisation in the offspring? A prospective, population-based study. Drug Saf. 2013;36(8):627-633. https://doi.org/10.1007/s40264-013-0078-y
  • Avcı B, Kaptan A. Comparison of mobile application-based teledentistry method wıth face-to-face oral examination assessment. Contemp Pediatr Dent 2023:4(1):15-31.
  • Petersen PE, Baez RJ. Oral Health Surveys: Basic Methods, 5th ed. World Health Organization; 2013.
  • Monse B, Heinrich-Weltzien R, Benzian H, Holmgren C, Van Palenstein Helderman W. PUFA – An index of clinical consequences of untreated dental caries. Community Dentistry and Oral Epidemiology. 2010;38: 77–82. https://doi.org/10.1111/j.1600-0528.2009.00514.x
  • Karakaya E, Sonmez H. The relationship between hypomineralized second primary molars and molar ıncisor hypomineralization in a group of school-aged children in Turkey. European Journal of General Dentistry. 2021;10: 65–72. https://doi.org/10.1055/s-0041-1732951
  • Singh R, Srivastava B, Gupta N. Prevalence and pattern of hypomineralized second primary molars in children in Delhi–NCR. Int J Clin Pediatr Dent. 2020;13(5):501–503. https://doi.org/10.5005/jp-journals-10005-1828
  • Meer Z, Almalki AY. Prevalence of Hypomineralization in second primary molars (HSPM) in 7 to 10-year-old Saudi children. Journal of Research in Medical and Dental Science. 2020;8(5):124–127.
  • Oyedele TA, Folayan MO, Oziegbe EO. Hypomineralised second primary molars: prevalence, pattern and associated co morbidities in 8- to 10-year-old children in Ile-Ife, Nigeria. BMC Oral Health. 2016;16(1):65. https://doi.org/10.1186/s12903-016-0225-9
  • Ghanim A, Manton D, Marino˜ R, Morgan M, Bailey D. Prevalence of demarcated hypomineralisation defects in second primary molars in Iraqi children. Int J Paediatr Dent. 2013;23:48–55. https://doi.org/10.1111/j.1365-263X.2012.01223.x
  • Elfrink M, Ghanim A, Manton D, Weerheijm K. Standardised studies on molar incisor hypomineralisation (MIH) and hypomineralised second primary molars (HSPM): a need. Eur Arch Paediatr Dent. 2015;16(3):247–255. https://doi.org/10.1007/s40368-015-0179-7
  • Goyal A, Dhareula A, Gauba K, Bhatia SK. Prevalence, defect characteristics and distribution of other phenotypes in 3- to 6-year-old children affected with Hypomineralised Second Primary Molars. Eur Arch Paediatr Dent. 2019;20:585–593. https://doi.org/10.1007/s40368-019-00441-9
  • Sidhu N, Wang Y, Barrett E, Casas M. Prevalence and presentation patterns of enamel hypomineralisation (MIH and HSPM) among paediatric hospital dental patients in Toronto, Canada: a cross-sectional study. Eur Arch Paediatr Dent. 2020;21(2): 263–270. https://doi.org/10.1007/s40368-019-00477-x
  • William R. Proffit, Henry Fields, Brent Larson, David M. Sarver. Contemporary Orthodontics. Elsevier Health Sciences 6; 2018.
  • Velló MA, Martínez-Costa C, Catalá M, Fons J, Brines J, Guijarro-Martínez R. Prenatal and neonatal risk factors for the development of enamel defects in low birth weight children. Oral Dis. 2010;16: 257–262. https://doi.org/10.1111/j.1601-0825.2009.01629.x
  • Devi K P, Goyal A, Gauba K, Bharti B, Jaiswal M, Gupta A, Singh SK. Prenatal, perinatal and postnatal risk factors associated with hypomineralised second primary molars – A cross-sectional study. Pediatric Dental Journal. 2023;33:159–166. https://doi.org/10.1016/j.pdj.2023.06.002
  • Masumo R, Bårdsen A, Åstrøm AN. Developmental defects of enamel in primary teeth and association with early life course events: a study of 6–36 month old children in Manyara, Tanzania. BMC Oral Health. 2013;13:21. https://doi.org/10.1186/1472-6831-13-21
  • Gambetta-Tessini K, Mariño R, Ghanim A, Calache H, Manton DJ. Carious lesion severity and demarcated hypomineralized lesions of tooth enamel in schoolchildren from Melbourne, Australia. Aust Dent J. 2018;63:365–373. https://doi.org/10.1111/adj.12626
  • Gambetta-Tessini K, Mariño R, Ghanim A, Calache H, Manton DJ. The impact of MIH/HSPM on the carious lesion severity of schoolchildren from Talca. Chile. Eur Arch Paediatr Dent. 2019;20(5):417–423. https://doi.org/10.1007/s40368-019-00416-w
  • Ghanim AM, Morgan MV, Mariño RJ, Bailey DL, Manton DJ. Risk factors of hypomineralised second primary molars in a group of Iraqi schoolchildren. Eur Arch Paediatr Dent. 2012;13(3):111–118. https://doi.org/10.1007/BF03262856
  • Serna Muñoz C, Ortiz Ruiz AJ, Pérez Silva A, Bravo-González LA, Vicente A. Second primary molar hypomineralisation and drugs used during pregnancy and infancy. A systematic review. Clin Oral Investig. 2020;24:1287–1297. https://doi.org/10.1007/s00784-019-03007-7
  • Lopes-Fatturi A, Menezes JVNB, Fraiz FC, Assunção LR da S, de Souza JF. Systemic exposures associated with hypomineralized primary second molars. Pediatr Dent. 2019;15;41(5):364-370.
  • Silva MJ, Kilpatrick NM, Craig JM, Manton DJ, Leong P, Burgner D, Scurrah KJ. Etiology of hypomineralized second primary molars: A prospective twin study. J Dent Res. 2019;98(1):77–83. https://doi.org/10.1177/0022034518792870
  • Infant and young child feeding. [Accessed: 17 August 2024]. Available at: https://www.who.int/en/news-room/fact-sheets/detail/infant-and-young-child-feeding
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There are 49 citations in total.

Details

Primary Language English
Subjects Paedodontics
Journal Section Articles
Authors

Elif Nahide Taşçı 0000-0002-7283-9898

Nagehan Yılmaz 0000-0001-9523-2899

Merve Nur Öztürk 0009-0006-5211-647X

Hüsna Selin Takaoğlu 0000-0002-0742-4784

Tamer Tuzuner 0000-0001-5817-5928

Early Pub Date September 30, 2025
Publication Date September 30, 2025
Submission Date February 16, 2025
Acceptance Date June 16, 2025
Published in Issue Year 2025 Volume: 15 Issue: 3

Cite

APA Taşçı, E. N., Yılmaz, N., Öztürk, M. N., … Takaoğlu, H. S. (2025). Prevalence of Hypomineralized Second Primary Molars and Associated Factors in Preschool Children in Trabzon, Türkiye: A cross-sectional study. Clinical and Experimental Health Sciences, 15(3), 602-611. https://doi.org/10.33808/clinexphealthsci.1637133
AMA Taşçı EN, Yılmaz N, Öztürk MN, Takaoğlu HS, Tuzuner T. Prevalence of Hypomineralized Second Primary Molars and Associated Factors in Preschool Children in Trabzon, Türkiye: A cross-sectional study. Clinical and Experimental Health Sciences. September 2025;15(3):602-611. doi:10.33808/clinexphealthsci.1637133
Chicago Taşçı, Elif Nahide, Nagehan Yılmaz, Merve Nur Öztürk, Hüsna Selin Takaoğlu, and Tamer Tuzuner. “Prevalence of Hypomineralized Second Primary Molars and Associated Factors in Preschool Children in Trabzon, Türkiye: A Cross-Sectional Study”. Clinical and Experimental Health Sciences 15, no. 3 (September 2025): 602-11. https://doi.org/10.33808/clinexphealthsci.1637133.
EndNote Taşçı EN, Yılmaz N, Öztürk MN, Takaoğlu HS, Tuzuner T (September 1, 2025) Prevalence of Hypomineralized Second Primary Molars and Associated Factors in Preschool Children in Trabzon, Türkiye: A cross-sectional study. Clinical and Experimental Health Sciences 15 3 602–611.
IEEE E. N. Taşçı, N. Yılmaz, M. N. Öztürk, H. S. Takaoğlu, and T. Tuzuner, “Prevalence of Hypomineralized Second Primary Molars and Associated Factors in Preschool Children in Trabzon, Türkiye: A cross-sectional study”, Clinical and Experimental Health Sciences, vol. 15, no. 3, pp. 602–611, 2025, doi: 10.33808/clinexphealthsci.1637133.
ISNAD Taşçı, Elif Nahide et al. “Prevalence of Hypomineralized Second Primary Molars and Associated Factors in Preschool Children in Trabzon, Türkiye: A Cross-Sectional Study”. Clinical and Experimental Health Sciences 15/3 (September2025), 602-611. https://doi.org/10.33808/clinexphealthsci.1637133.
JAMA Taşçı EN, Yılmaz N, Öztürk MN, Takaoğlu HS, Tuzuner T. Prevalence of Hypomineralized Second Primary Molars and Associated Factors in Preschool Children in Trabzon, Türkiye: A cross-sectional study. Clinical and Experimental Health Sciences. 2025;15:602–611.
MLA Taşçı, Elif Nahide et al. “Prevalence of Hypomineralized Second Primary Molars and Associated Factors in Preschool Children in Trabzon, Türkiye: A Cross-Sectional Study”. Clinical and Experimental Health Sciences, vol. 15, no. 3, 2025, pp. 602-11, doi:10.33808/clinexphealthsci.1637133.
Vancouver Taşçı EN, Yılmaz N, Öztürk MN, Takaoğlu HS, Tuzuner T. Prevalence of Hypomineralized Second Primary Molars and Associated Factors in Preschool Children in Trabzon, Türkiye: A cross-sectional study. Clinical and Experimental Health Sciences. 2025;15(3):602-11.

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