Comparison of distribution of blood groups in inflammatory rheumatic diseases and healthy subjects

Yıl 2019, Cilt: 41 Sayı: 3, 516 - 523, 30.09.2019

Ahmet Karadağ

https://doi.org/10.7197/cmj.vi.588232

Cited By: 2

Öz

Objective: The present study investigates whether a relationship
exists between the ABO and Rh blood groups and the type of rheumatic disease in
patients with inflammatory rheumatic disease.

Method: The present study was based on the data of
1,272 healthy subjects and 1,028 patients with an inflammatory rheumatic
disease who were followed up in our clinic between June 2016 and January 2019.
The type of rheumatic disease and the ABO and Rh blood groups of the
participants were recorded.

Results: The A blood group was more prevalent in patients with inflammatory
rheumatic disease and in the healthy subjects, followed by the O, B and AB
blood groups in respective order, although there was no significant difference
between the ABO groups in terms of distribution(p>0.05). The Rh (+) blood
group was more prevalent than Rh (-) in both groups, although there was a
statistically significant difference in terms of the distribution of the Rh
blood group among the groups(p<0.05). According to
the results of a logistic regression analysis, the Rh (-) blood type decreases
the likelihood of developing a rheumatic disease (p<0.05).

Conclusions:
The A and Rh (+) blood groups were more
commonly observed in patients with inflammatory rheumatic diseases, followed by
the O, B and AB blood groups. Furthermore,
patients with the Rh (-) blood type were less likely to develop rheumatic
disease. The present study may serve as a guide for
future clinical studies evaluating the relationship between rheumatic diseases
and blood types in terms of genetic predisposition and pathogenesis.

Anahtar Kelimeler

Rheumatic diseases, ABO blood groups

Kaynakça

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