NITRILES IN HETEROCYCLIC SYNTHESIS A NEW SYNTHESIS OF N-AMINOPYRIDINES

Year 1985, Volume: 31 , 0 - 0, 01.01.1985

E. A. A. Hafez

https://doi.org/10.1501/Commub_0000000257

Abstract

A novel synthesis of N-Phenyl aminopyridone via the reaction of cyanoacetphenylhydrazide and ylidene malononitrile is reported.
in the last few years we have been interested in development of new procedures for synthesis of polyfunctionally substituted azoles and azines of potential synthetic and biological interest[l-3]. In continuat- ion of this work ve investigated the reactivity of cyanoacetphenylhyd- drazide I with some cinnamonitrile derivatives. Soto et al [4] have rc- cently reported that the reaction of benzylidene cinnamonitrile 2 b with cyanoacethydrazide affords N-aminopyridine derivative, formed via Michael addition, cyclization and oxidation of the formed hydropyridine derivative.

Keywords

NITRILES IN HETEROCYCLIC, SYNTHESIS, N-AMINOPYRIDINES

References

• Communications Faculty of Sciences University of Ankara Series B Chemistry and Chemical Engineering