Serum Vitamin D Among Patients withType 2 Diabetes Mellitus
Abstract
Vitamin D supplements are a beneficial health issue to benefit from insulin therapy. In those with T2DM, serum vit-D was checked and resuscitated. Serum vit-D was evaluated with its rich content. Serum vit D levels were statistically significantly lower in T2DM patients than in the control group. It was found to be significant in terms of the relationship between fasting blood sugar and vit-D and HbA1C. Vit-D in sugar will be used as a benefit from vit-D in patients with blood T2DM patients. The mean±SD vit-D level was 19.22±9.23 for the whole population with a fasting blood glucose level of 110 mg/dl or less, and 12.21±6.15 for people with a fasting blood glucose level above 130 mg/dl, and p<0.001. The relationship between vit-D level and fasting blood sugar is statistically significant with negative pearson correlation coefficient. Vit-D mean±SD 20.46±8.56 for the entire population with an HbA1C level equal to or lower than 6.5%, and 12.84±6% for individuals with a fasting blood glucose level above 6.5%, is 26 and p<0.001. The strong relationship between vit-D and fasting blood glucose and HbA1C is due to the fact that vit-D tends to specifically stimulate insulin production in β-pancreatic cells via the nuclear vit-D receptor (VDR) and that vit-D minimizes inflammation. Vit-D supplements are a beneficial health challenge to benefit from insulin therapy. Serum vit-D was checked in patients with T2DM. The serum has been evaluated with its rich content of vit-D. Serum vit-D levels were statistically significantly lower in T2DM patients compared to the control group. It was found to be significant in terms of the relationship between fasting blood sugar and vit-D and HbA1C. Vit-D in sugar will be used as a benefit from vit-D in blood T2DM patients.
Keywords: Vitamin D, Serum, Type 2 Diabetes Mellitus, Human.
Keywords: Vitamin D, Serum, Type 2 Diabetes Mellitus, Human.
Keywords
References
- [1] Adela R., Borkar R.M., Bhandi M.M., Vishwakarma Reddy P.N.C., Srinivas R., Banerjee S., Lower Vitamin D Metabolites Levels were Associated with Increased Coronary Artery Diseases in Type 2 Diabetes Patients in India, Sci. Rep., 6(12) (2016) 1–13.
- [2] Yassin M.M., Masoud A.E.R.D., Serum Vitamin D Status in Type 2 Diabetic Patients from Gaza Strip, Diabetes Metab., 13(3) (2019) 1865–1870.
- [3] Risérus U., Willett W.C., Hu F.B., Dietary Fats and Prevention of T2DM, Prog. Lipid Res., 48(1) (2009) 44–51.
- [4] Holick M.F., Schnoes H.K., Deluca H.F., Suda T., Cousins R.J., Isolation and Identification of 1,25-Dihydroxycholecalciferol a Metabolite of Vitamin D Active in Intestine, Biochemistry, 10(14) (1971) 2799–2804.
- [5] Turner B., Williams S., Taichman D., Vijan S., The Clinic Type 2 Diabetes Screening and Prevention Diagnosis and Evaluation Practice Improvement CME Questions, 2010.
- [6] Giovannuc E., Harlan D.M., Archer M.C., Bergenstal R.M., Gapstur S.M., Habel L.A., Pollak M., Regensteiner J.G., Yee D., Diabetes and Cancer: A Consensus Rreport, Diabetes Care, 33(7) (2010)1674–1685.
- [7] Saad F., Gooren L., The Role of Testosterone in The Metabolic Syndrome: A Review, J.Steroid Biochem. Mol. Biol., 114 (2) (2009) 40–43.
- [8] D. O. F. Diabetes, Diagnosis and Classification of Diabetes Mellitus, Diabetes Care, 35(1) (2012).
- [9] Natha DM., Balkau B., Bonora E., Johnsen K B., Buse JB., Colagiuri S., Davidson MB.. DeFronzo R., Genuth S., Rury R. Holman RR., Ji L., Kirkman S., Knowler WC, Schatz D., Shaw J., Sobngwi E., Steffes M., Vaccaro O., Wareham N., Zinman B., International Expert Committe Report on The Role of the A1C, Assay in the Diagnosis of Diabetes, Diabetes Care, 32(7) (2009) 1327–1334.
- [10] Li G., Elley C.R., Kenealy T., Lifestyle İnterventions Rreduced the Long Term Risk of Diabetes in Adults with Impaired Glucose Tolerance, Evid. Based. Med.,13(6) (2008) 173.