Evaluation of Thalamus Volumes in Patients with Diabetic Polyneuropathy Using Magnetic Resonance Imaging Method

Ayşegül Öztürk; Vedat Sabancıoğulları; Yaşar Taştemur; İbrahim Öztoprak

doi:10.17776/csj.1144272

EN

Evaluation of Thalamus Volumes in Patients with Diabetic Polyneuropathy Using Magnetic Resonance Imaging Method

Abstract

The neurological process in diabetes is not limited to peripheral nerves but also affects the central nervous system (CNS). In addition, magnetic resonance images (MRI) showing that this condition can occur early in the neuropathic process are also available. This study was conducted to investigate whether peripheral sensory nerve dysfunction causes changes in thalamus volume in patients with diabetic polyneuropathy (DPNP) who experience sensory loss. Our study is a retrospective study consisting of diabetes mellitus (DM), DPNP and a healthy control group, where brain MRI of 204 individuals aged between 20-90 with no neurological disorder that might affect thalamus. Morphometric measurements for thalamus and cerebrum volumetry were performed in conventional MRI. In order to measure the microstructural changes of thalamus, the apparent diffusion coefficient (ADC) was calculated by the diffusion-weighted imaging method. In conclusion of our measurements, it was found that individuals with DM and DPNP had a decrease in volume of both thalami(p<0.05) and cerebrum(p<0.05). However, no significant difference was found in ADC values(p>0.05). According to the results of research, DM and DPNP affect not only the peripheral nervous system but also the CNS. This effect caused atrophy of thalamus and cerebrum in patients of all age groups.

Keywords

Diabetes mellitus, Diabetic polyneuropathy, Thalamus, Magnetic resonance imaging.

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Details

Primary Language

English

Subjects

Structural Biology

Journal Section

Research Article

Authors

Ayşegül Öztürk ^*
0000-0001-8130-7968
Türkiye

Vedat Sabancıoğulları
0000-0001-9059-6554
Türkiye

Yaşar Taştemur
0000-0002-2016-0592
Türkiye

İbrahim Öztoprak
0000-0002-4334-0350
Türkiye

Publication Date

December 27, 2022

Submission Date

July 15, 2022

Acceptance Date

December 9, 2022

Published in Issue

Year 2022 Volume: 43 Number: 4

DOI

https://doi.org/10.17776/csj.1144272

IZ

https://izlik.org/JA58AZ54YP

APA

Öztürk, A., Sabancıoğulları, V., Taştemur, Y., & Öztoprak, İ. (2022). Evaluation of Thalamus Volumes in Patients with Diabetic Polyneuropathy Using Magnetic Resonance Imaging Method. Cumhuriyet Science Journal, 43(4), 569-576. https://doi.org/10.17776/csj.1144272

AMA

1.Öztürk A, Sabancıoğulları V, Taştemur Y, Öztoprak İ. Evaluation of Thalamus Volumes in Patients with Diabetic Polyneuropathy Using Magnetic Resonance Imaging Method. CSJ. 2022;43(4):569-576. doi:10.17776/csj.1144272

Chicago

Öztürk, Ayşegül, Vedat Sabancıoğulları, Yaşar Taştemur, and İbrahim Öztoprak. 2022. “Evaluation of Thalamus Volumes in Patients With Diabetic Polyneuropathy Using Magnetic Resonance Imaging Method”. Cumhuriyet Science Journal 43 (4): 569-76. https://doi.org/10.17776/csj.1144272.

EndNote

Öztürk A, Sabancıoğulları V, Taştemur Y, Öztoprak İ (December 1, 2022) Evaluation of Thalamus Volumes in Patients with Diabetic Polyneuropathy Using Magnetic Resonance Imaging Method. Cumhuriyet Science Journal 43 4 569–576.

IEEE

[1]A. Öztürk, V. Sabancıoğulları, Y. Taştemur, and İ. Öztoprak, “Evaluation of Thalamus Volumes in Patients with Diabetic Polyneuropathy Using Magnetic Resonance Imaging Method”, CSJ, vol. 43, no. 4, pp. 569–576, Dec. 2022, doi: 10.17776/csj.1144272.

ISNAD

Öztürk, Ayşegül - Sabancıoğulları, Vedat - Taştemur, Yaşar - Öztoprak, İbrahim. “Evaluation of Thalamus Volumes in Patients With Diabetic Polyneuropathy Using Magnetic Resonance Imaging Method”. Cumhuriyet Science Journal 43/4 (December 1, 2022): 569-576. https://doi.org/10.17776/csj.1144272.

JAMA

1.Öztürk A, Sabancıoğulları V, Taştemur Y, Öztoprak İ. Evaluation of Thalamus Volumes in Patients with Diabetic Polyneuropathy Using Magnetic Resonance Imaging Method. CSJ. 2022;43:569–576.

MLA

Öztürk, Ayşegül, et al. “Evaluation of Thalamus Volumes in Patients With Diabetic Polyneuropathy Using Magnetic Resonance Imaging Method”. Cumhuriyet Science Journal, vol. 43, no. 4, Dec. 2022, pp. 569-76, doi:10.17776/csj.1144272.

Vancouver

1.Ayşegül Öztürk, Vedat Sabancıoğulları, Yaşar Taştemur, İbrahim Öztoprak. Evaluation of Thalamus Volumes in Patients with Diabetic Polyneuropathy Using Magnetic Resonance Imaging Method. CSJ. 2022 Dec. 1;43(4):569-76. doi:10.17776/csj.1144272

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