In vıtro Antioxidant Properties of Novel Compound (1R, 2R) -1,2-bis- (5- (4- Hydroxynaphthalen-1-ylazo) - [1,3,4] Thiadiazol-2-YL) -Ethane- 1,2-Diole

Akif Evren Parlak; Pelin Koparır

doi:10.17776/csj.412123

TR EN

In vıtro Antioxidant Properties of Novel Compound (1R, 2R) -1,2-bis- (5- (4- Hydroxynaphthalen-1-ylazo) - [1,3,4] Thiadiazol-2-YL) -Ethane- 1,2-Diole

Abstract

1,3,4-Thiadiazoles have a variety of biological activities depending on their substituents. This study aims to investigate the in vitro antioxidant properties of 1R,2R -1,2-bis- (5- (4-hydroxynaphthalen-1-ylazo) - [1,3,4] thiadiazol-2-yl) -ethane- 1,2-diole novel compound. In this study, antioxidant activities were measured by different methods such as, DPPH^. radical scavenging activity, iron reducing power capacity, metal chelating activity and hydroxyl radical scavenging activity. As a result, it was determined that this new compound has effective antioxidant and free radical scavenging activity when compared to reference antioxidants such as BHT and α-tocopherol.

Keywords

antioxidant activity, radical scavenging activity, 1-3-4 Thiadiazol, biological activities, biological activities

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Details

Primary Language

English

Subjects

-

Journal Section

Research Article

Authors

Akif Evren Parlak ^*
Türkiye

Pelin Koparır
Türkiye

Publication Date

September 30, 2018

Submission Date

April 3, 2018

Acceptance Date

May 22, 2018

Published in Issue

Year 2018 Volume: 39 Number: 3

DOI

https://doi.org/10.17776/csj.412123

IZ

https://izlik.org/JA49PP77ZU

APA

Parlak, A. E., & Koparır, P. (2018). In vıtro Antioxidant Properties of Novel Compound (1R, 2R) -1,2-bis- (5- (4- Hydroxynaphthalen-1-ylazo) - [1,3,4] Thiadiazol-2-YL) -Ethane- 1,2-Diole. Cumhuriyet Science Journal, 39(3), 658-667. https://doi.org/10.17776/csj.412123

AMA

1.Parlak AE, Koparır P. In vıtro Antioxidant Properties of Novel Compound (1R, 2R) -1,2-bis- (5- (4- Hydroxynaphthalen-1-ylazo) - [1,3,4] Thiadiazol-2-YL) -Ethane- 1,2-Diole. CSJ. 2018;39(3):658-667. doi:10.17776/csj.412123

Chicago

Parlak, Akif Evren, and Pelin Koparır. 2018. “In Vıtro Antioxidant Properties of Novel Compound (1R, 2R) -1,2-Bis- (5- (4- Hydroxynaphthalen-1-Ylazo) - [1,3,4] Thiadiazol-2-YL) -Ethane- 1,2-Diole”. Cumhuriyet Science Journal 39 (3): 658-67. https://doi.org/10.17776/csj.412123.

EndNote

Parlak AE, Koparır P (September 1, 2018) In vıtro Antioxidant Properties of Novel Compound (1R, 2R) -1,2-bis- (5- (4- Hydroxynaphthalen-1-ylazo) - [1,3,4] Thiadiazol-2-YL) -Ethane- 1,2-Diole. Cumhuriyet Science Journal 39 3 658–667.

IEEE

[1]A. E. Parlak and P. Koparır, “In vıtro Antioxidant Properties of Novel Compound (1R, 2R) -1,2-bis- (5- (4- Hydroxynaphthalen-1-ylazo) - [1,3,4] Thiadiazol-2-YL) -Ethane- 1,2-Diole”, CSJ, vol. 39, no. 3, pp. 658–667, Sept. 2018, doi: 10.17776/csj.412123.

ISNAD

Parlak, Akif Evren - Koparır, Pelin. “In Vıtro Antioxidant Properties of Novel Compound (1R, 2R) -1,2-Bis- (5- (4- Hydroxynaphthalen-1-Ylazo) - [1,3,4] Thiadiazol-2-YL) -Ethane- 1,2-Diole”. Cumhuriyet Science Journal 39/3 (September 1, 2018): 658-667. https://doi.org/10.17776/csj.412123.

JAMA

1.Parlak AE, Koparır P. In vıtro Antioxidant Properties of Novel Compound (1R, 2R) -1,2-bis- (5- (4- Hydroxynaphthalen-1-ylazo) - [1,3,4] Thiadiazol-2-YL) -Ethane- 1,2-Diole. CSJ. 2018;39:658–667.

MLA

Parlak, Akif Evren, and Pelin Koparır. “In Vıtro Antioxidant Properties of Novel Compound (1R, 2R) -1,2-Bis- (5- (4- Hydroxynaphthalen-1-Ylazo) - [1,3,4] Thiadiazol-2-YL) -Ethane- 1,2-Diole”. Cumhuriyet Science Journal, vol. 39, no. 3, Sept. 2018, pp. 658-67, doi:10.17776/csj.412123.

Vancouver

1.Akif Evren Parlak, Pelin Koparır. In vıtro Antioxidant Properties of Novel Compound (1R, 2R) -1,2-bis- (5- (4- Hydroxynaphthalen-1-ylazo) - [1,3,4] Thiadiazol-2-YL) -Ethane- 1,2-Diole. CSJ. 2018 Sep. 1;39(3):658-67. doi:10.17776/csj.412123

Cited By

Novel Bis-1,3,4-Thiadiazoles Derivatives: Synthesis, Spectroscopic Characterization, DFT Calculations and Evaluation of their Antimicrobial and Antioxidant Activities

Cumhuriyet Science Journal

https://doi.org/10.17776/csj.1221864

As of 2026, Cumhuriyet Science Journal will be published in six issues per year, released in February, April, June, August, October, and December

(1R, 2R) -1,2-BIS- (5- (4-Hidroksinaftalin-1- İlazo) - [1, 3,4] Tiyadiazol-2- Diol Yeni Bileşiğinin İn vitro Antioksidan Özellikleri

Abstract

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In vıtro Antioxidant Properties of Novel Compound (1R, 2R) -1,2-bis- (5- (4- Hydroxynaphthalen-1-ylazo) - [1,3,4] Thiadiazol-2-YL) -Ethane- 1,2-Diole

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Novel Bis-1,3,4-Thiadiazoles Derivatives: Synthesis, Spectroscopic Characterization, DFT Calculations and Evaluation of their Antimicrobial and Antioxidant Activities