Investigation of Antitumor and Antibacterial Properties of Some New Thiophene-2,5-Dicarboxylic Acid bis-aryl (alkyl) amide Compounds

Pelin Koparır; Akif Evren Parlak

doi:10.17776/csj.412145

TR EN

Investigation of Antitumor and Antibacterial Properties of Some New Thiophene-2,5-Dicarboxylic Acid bis-aryl (alkyl) amide Compounds

Abstract

Thiophene-derived compounds are of interest in chemistry, biology and pharmacology because of their various pharmacological activities This study aims to investigate the antitumor and antibacterial activity of thiophene-2,5-dicarboxylic acid bis-aryl (alkyl) amide compounds. In this study, the properties of antibacterial and antitumor were determined in vitro media, for all compounds.

As a result, cell viability experiments show that some of this compounds have effective in vitro antitumor activity. In addition, it has also been found that some compounds have an effective antibacterial activity

Keywords

Thiophene-derived compounds,antibacterial activity,antimicrobial activities,antitumor activity,cancer

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Details

Primary Language

English

Subjects

-

Journal Section

Research Article

Authors

Pelin Koparır
Türkiye

Akif Evren Parlak ^*
Türkiye

Publication Date

June 29, 2018

Submission Date

April 3, 2018

Acceptance Date

May 22, 2018

Published in Issue

Year 2018 Volume: 39 Number: 2

DOI

https://doi.org/10.17776/csj.412145

IZ

https://izlik.org/JA92SJ33TD

APA

Koparır, P., & Parlak, A. E. (2018). Investigation of Antitumor and Antibacterial Properties of Some New Thiophene-2,5-Dicarboxylic Acid bis-aryl (alkyl) amide Compounds. Cumhuriyet Science Journal, 39(2), 357-365. https://doi.org/10.17776/csj.412145

AMA

1.Koparır P, Parlak AE. Investigation of Antitumor and Antibacterial Properties of Some New Thiophene-2,5-Dicarboxylic Acid bis-aryl (alkyl) amide Compounds. CSJ. 2018;39(2):357-365. doi:10.17776/csj.412145

Chicago

Koparır, Pelin, and Akif Evren Parlak. 2018. “Investigation of Antitumor and Antibacterial Properties of Some New Thiophene-2,5-Dicarboxylic Acid Bis-Aryl (alkyl) Amide Compounds”. Cumhuriyet Science Journal 39 (2): 357-65. https://doi.org/10.17776/csj.412145.

EndNote

Koparır P, Parlak AE (June 1, 2018) Investigation of Antitumor and Antibacterial Properties of Some New Thiophene-2,5-Dicarboxylic Acid bis-aryl (alkyl) amide Compounds. Cumhuriyet Science Journal 39 2 357–365.

IEEE

[1]P. Koparır and A. E. Parlak, “Investigation of Antitumor and Antibacterial Properties of Some New Thiophene-2,5-Dicarboxylic Acid bis-aryl (alkyl) amide Compounds”, CSJ, vol. 39, no. 2, pp. 357–365, June 2018, doi: 10.17776/csj.412145.

ISNAD

Koparır, Pelin - Parlak, Akif Evren. “Investigation of Antitumor and Antibacterial Properties of Some New Thiophene-2,5-Dicarboxylic Acid Bis-Aryl (alkyl) Amide Compounds”. Cumhuriyet Science Journal 39/2 (June 1, 2018): 357-365. https://doi.org/10.17776/csj.412145.

JAMA

1.Koparır P, Parlak AE. Investigation of Antitumor and Antibacterial Properties of Some New Thiophene-2,5-Dicarboxylic Acid bis-aryl (alkyl) amide Compounds. CSJ. 2018;39:357–365.

MLA

Koparır, Pelin, and Akif Evren Parlak. “Investigation of Antitumor and Antibacterial Properties of Some New Thiophene-2,5-Dicarboxylic Acid Bis-Aryl (alkyl) Amide Compounds”. Cumhuriyet Science Journal, vol. 39, no. 2, June 2018, pp. 357-65, doi:10.17776/csj.412145.

Vancouver

1.Pelin Koparır, Akif Evren Parlak. Investigation of Antitumor and Antibacterial Properties of Some New Thiophene-2,5-Dicarboxylic Acid bis-aryl (alkyl) amide Compounds. CSJ. 2018 Jun. 1;39(2):357-65. doi:10.17776/csj.412145

Cited By

Synthesis, X-ray structure, antimicrobial activity, DFT and molecular docking studies of N-(thiophen-2-ylmethyl)thiophene-2-carboxamide

Acta Crystallographica Section C Structural Chemistry

https://doi.org/10.1107/S2053229622006283

As of 2026, Cumhuriyet Science Journal will be published in six issues per year, released in February, April, June, August, October, and December

Bazı Yeni Tiyofen-2,5 Dikarboksilik Asit bis-aril (alkil) amid Bileşiklerinin Antitümör ve Antibakteriyel Özelliklerinin İncelenmesi

Abstract

Keywords

Investigation of Antitumor and Antibacterial Properties of Some New Thiophene-2,5-Dicarboxylic Acid bis-aryl (alkyl) amide Compounds

Abstract

Keywords

References

Details

Primary Language

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Journal Section

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Acceptance Date

Published in Issue

DOI

IZ

Cite

Cited By

Synthesis, X-ray structure, antimicrobial activity, DFT and molecular docking studies of N-(thiophen-2-ylmethyl)thiophene-2-carboxamide