Fungus-mediated synthesis of silver nanoparticles (agnp) and inhibitory effect on aspergillus spp. in combination with antifungal agent

Nevcihan Gürsoy

doi:10.17776/csj.653627

EN

Fungus-mediated synthesis of silver nanoparticles (agnp) and inhibitory effect on aspergillus spp. in combination with antifungal agent

Abstract

In this study, A. niger synthesized silver nanoparticules (AgNP) were characterised by using UV-Vis Sphecthrofotometry, Atomic Force Microscopy (AFM) and Transmission Electron Microscope (TEM) Analysis. The antifungal effect of synthesised AgNP and antifungal agent Amphothericin B (Amp-B) combination were investigated against Aspergillus spp. Antimicrobial efficiency were evaluated by Kirby Bauer Agar Disk Diffusion Test. In the end of this study, the particule size of AgNP which biosynthesised on A. niger were measured between 13.2-646.8 nm by AFM. The TEM analysis of AgNPs synthesized on A. niger were determined as a spherical in shape with different sizes 25.5-543.3 nm in the examined regions. The development of antifungal inhibition zone on A. niger and A. flavus was respectively carried out to evaluate on application of A. niger-AgNP; between 0-0.67 mm, 0-0.42 mm, Amp-B; 0.70-1.50 mm, 0- 0.65 mm, A. niger-AgNP+Amp-B; 1.14-2.00 mm, 0-1 mm. According to this study data, antifungal effect of were respectively determined %0.4, %1.4, %2.4; %0.1, %0.45, %0.65 on A. niger and A. flavus. The antifungal inhibition zone occurrence indicated depent of both fungi results, the Amp-B were increase %43.91 of A. niger-AgNP; A. niger-AgNP+Amp-B % 40.84 of Amp-B, A. niger-AgNP+Amp-B% 84.75 of A. niger-AgNP. The statistical evaluation of this study showed that multiple comparison of three application on A. niger and A. flavus were significant (p˂0,005).

Keywords

A. niger,A. flavus,AgNPs,Amp-B,Antimicrobial

Supporting Institution

Scientific Research Council of Sivas Cumhuriyet University

Project Number

CÜBAP M-450

Thanks

This study was supported financially by the Scientific Research Council of Sivas Cumhuriyet University (CÜBAP M-450).

References

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Details

Primary Language

English

Subjects

Engineering

Journal Section

Research Article

Authors

Nevcihan Gürsoy ^*
0000-0002-6573-0763
Türkiye

Publication Date

March 22, 2020

Submission Date

December 1, 2019

Acceptance Date

February 3, 2020

Published in Issue

Year 2020 Volume: 41 Number: 1

DOI

https://doi.org/10.17776/csj.653627

IZ

https://izlik.org/JA38DZ78ZL

APA

Gürsoy, N. (2020). Fungus-mediated synthesis of silver nanoparticles (agnp) and inhibitory effect on aspergillus spp. in combination with antifungal agent. Cumhuriyet Science Journal, 41(1), 311-318. https://doi.org/10.17776/csj.653627

AMA

1.Gürsoy N. Fungus-mediated synthesis of silver nanoparticles (agnp) and inhibitory effect on aspergillus spp. in combination with antifungal agent. CSJ. 2020;41(1):311-318. doi:10.17776/csj.653627

Chicago

Gürsoy, Nevcihan. 2020. “Fungus-Mediated Synthesis of Silver Nanoparticles (agnp) and Inhibitory Effect on Aspergillus Spp. In Combination With Antifungal Agent”. Cumhuriyet Science Journal 41 (1): 311-18. https://doi.org/10.17776/csj.653627.

EndNote

Gürsoy N (March 1, 2020) Fungus-mediated synthesis of silver nanoparticles (agnp) and inhibitory effect on aspergillus spp. in combination with antifungal agent. Cumhuriyet Science Journal 41 1 311–318.

IEEE

[1]N. Gürsoy, “Fungus-mediated synthesis of silver nanoparticles (agnp) and inhibitory effect on aspergillus spp. in combination with antifungal agent”, CSJ, vol. 41, no. 1, pp. 311–318, Mar. 2020, doi: 10.17776/csj.653627.

ISNAD

Gürsoy, Nevcihan. “Fungus-Mediated Synthesis of Silver Nanoparticles (agnp) and Inhibitory Effect on Aspergillus Spp. In Combination With Antifungal Agent”. Cumhuriyet Science Journal 41/1 (March 1, 2020): 311-318. https://doi.org/10.17776/csj.653627.

JAMA

1.Gürsoy N. Fungus-mediated synthesis of silver nanoparticles (agnp) and inhibitory effect on aspergillus spp. in combination with antifungal agent. CSJ. 2020;41:311–318.

MLA

Gürsoy, Nevcihan. “Fungus-Mediated Synthesis of Silver Nanoparticles (agnp) and Inhibitory Effect on Aspergillus Spp. In Combination With Antifungal Agent”. Cumhuriyet Science Journal, vol. 41, no. 1, Mar. 2020, pp. 311-8, doi:10.17776/csj.653627.

Vancouver

1.Nevcihan Gürsoy. Fungus-mediated synthesis of silver nanoparticles (agnp) and inhibitory effect on aspergillus spp. in combination with antifungal agent. CSJ. 2020 Mar. 1;41(1):311-8. doi:10.17776/csj.653627

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Fungus-mediated synthesis of silver nanoparticles (agnp) and inhibitory effect on aspergillus spp. in combination with antifungal agent

Abstract

Project Number

Fungus-mediated synthesis of silver nanoparticles (agnp) and inhibitory effect on aspergillus spp. in combination with antifungal agent

Abstract

Keywords

Supporting Institution

Project Number

Thanks

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

DOI

IZ

Cite

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