A STUDY ON THE USE OF DIFFERENT MATERIALS COMBINED WITH ALLOGRAFT ON OSSEOINTEGRATION AND BONE REGENERATION OF DENTAL IMPLANTS WITH CORONAL DEFECTS IN A RABBIT MODEL

Yıl 2020, Cilt: 23 Sayı: 3, 232 - 239, 05.10.2020

Oğuzhan Mehmet Elmalı İlknur Eninanç Defne Yeler Ceylan Hepokur Yener Ünal Hasan Yeler

https://doi.org/10.7126/cumudj.712055

Öz

Objectives: To assess differential effects of different materials combined with allograft on bone-to-implant contact and newly formed bone formation in dental implants with coronal defects histomorphometrically.
Materials and Methods: The study was conducted on 24 male New Zealand white rabbits. Dental implants (3.0 × 10 mm) were placed at the center of defects (9 mm diameter, 4 mm depth) created in the tibial bones of the rabbits. Graft (GF, n=8), graft + rifamycin (GR, n=8), and graft + black cumin oil via orogastric route (GB, n=8) were applied on the coronal aspects of the implants for 28 days. Undecalcified histomorphometric analyses were conducted on slides stained with toluidine blue.
Results: Bone-to-implant contact was 46.57% ± 3.59% in the graft, 67.12% ± 3.64% in the graft+rifamycin, and 55.62% ± 4.37% in the graft+black cumin oil groups. The percentage of new bone formation at the defect area was 34.71% ± 4.11% in the graft, 55.37% ± 4.89% in the graft + rifamycin, and 45.75% ± 3.69% in the graft + black cumin oil groups. In terms of new bone formation and bone-to-implant contact, graft + rifamycin and graft + black cumin oil groups were significantly different from the graft group. The differences between the graft + rifamycin and graft + black cumin oil groups were also statistically significant.
Conclusion: Allogreft + rifamycin and orogastric black cumin oil were found to have positive effects on bone healing at sites with coronal defects. Rifamycin showed significantly greater favorable effects on bone-to-implant contact and new bone formation compared to black cumin oil.

Anahtar Kelimeler

Allograft, Rifamycin, Black Cumin Oil, Histomorphometry, Dental Implant

Destekleyen Kurum

Scientific Research Project Fund of Sivas Cumhuriyet University (CÜBAP)

Proje Numarası

DIS-158

Teşekkür

The authors thank Dr. Erdem KILIÇ from the Erciyes University Oral and Maxillofacial Surgery Department for his support in the research laboratory work.

Kaynakça

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