Evaluation of some antinutritional and goitrogenic components of cannabis consumed in Sokoto, Nigeria

Year 2023, Volume: 2 Issue: 2, 11 - 16, 30.06.2023

Aminu Umar Imam Yusuf Sarkingobir

Abstract

There is rising prevalence of abuse of cannabis in Sokoto. However, a number of studies had revealed the health effects of this drug which are supposed to be due to the contents of the cannabis drug. Therefore, the concern of this evaluation was an assessment of the concentrations of goitrogens (calcium, magnesium, chloride, fluoride, cyanide, and nitrate); antinutritional factors (phytate, flavonoids, saponins, tannins, and relations) and iodine present in cannabis drug being abused in Sokoto, Nigeria. Standard methods and procedures were utilized for the determination of goitrogens, antinutritional factors, and iodine in cannabis. The result shows the concentration of calcium (203.1±0.01 to 250.3±0.01 ppm), magnesium (10.1±1.5 to102±5.1 ppm), and iodine (0.064±0.01 to1.70±0.05 ppm) determined in cannabis. The antinutrients found are: Cyanide (47.0±0.01-60.0±2.10 ppm), chloride (1.2±10.05-1.4±10.05ppm), fluoride (0.9±0.01-1.9±0.01 ppm), and nitrate (1.3±0.1-2.02±0.01 ppm). The observed antinutrients are: Phytate (7.1±0.001-8.0±0.1ppm), flavonoids (200.0±1.2-250.0±1.3ppm), saponins (30.0±0.05-35.1±0.04 ppm), tannins (200.2±1.0-233.1±1.0ppm) and oxalate (14.2±0.05-20.1±0.5ppm). Therefore, this drug has significant levels (at p<0.005 significant level) of chemicals that can elicit toxicity effects in acute or chronic consumption, care need to be taken to shun drug abuse at all cost.

Keywords

Cannabis,, antinutrients, gotre, goitrogens, cyanide, calcium

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