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Yıl 2020, Cilt 3, Sayı 2, 97 - 103, 24.12.2020
https://doi.org/10.38093/cupmap.765089

Öz

Kaynakça

  • Adnan M, Ullah I, Tariq A, Murad W, Azizullah A, Khan A, Ali N. 2014. Ethnomedicine use in the war affected region of Northwest Pakistan. J Ethnobiol Ethnomed 10: 16.
  • Ali N, Shah SW, Shah I, Ahmed G, Ghias M, Khan I. Cytotoxic and anthelmintic potential of crude saponins isolated from Achillea wilhelmsii C. Koch and Teucrium stocksianum Boiss. BMC Complement Altern Med 2011;11:106.
  • Bisset NG.1994. Herbal Drugs and Phytopharmaceuticals: A handbook for practice scientific basis (1st ed.). Stuttgart, Germany: Medpharm GmbH Scientifiv Publisher.
  • Bozin B, Mimica Dukic N, Bogavac M, Suvajdzic L, Simin N, Samojlik I, et al. 2008. Chemical composition, antioxidant and antibacterial properties of Achillea collina Becker ex Heimerl s.l. and A. pannonica Scheele essential oils. Molecules 13: 2058 68.
  • de Sousa AC, Alviano DS, Blank AF, Alves PB, Alviano CS, Gattass CR. 2004. Melissa officinalis L. essential oil: antitumoral and antioxidant activities. J Pharm Parmacol 56: 677-681.
  • Demir S, Ayazoglu Demir E, Aliyazicioglu Y, 2020. Selective Cytotoxic Effect of Astaxanthin on Human Lung and Colon Cancer Cells. KSU J. Agric Nat 23 (6): 1489-1494.
  • Elif Burcu Bali, Leyla Açık, Pınar Elçi, Meral Sarper, Ferit Avcu and Mecit Vural. 2015. In vitro anti-oxidant, cytotoxic and pro-apoptotic effects of Achillea teretifolia Willd extracts on human prostate cancer cell lines. Pharmacogn Mag. Oct; 11(Suppl 2): S308–S315.
  • Encalada, M. A., Hoyos, K. M., Rehecho, S., Berasategi, I., de Ciriano, M. G. Í., Ansorena, D., ... & Calvo, M. I. (2011). Anti-proliferative effect of Melissa officinalis on human colon cancer cell line. Plant Foods for Human Nutrition, 66(4), 328-334.
  • Ferlay J, Shim HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 2010; 127(1): 2893-917.
  • Filip Grbović, Milan S. Stanković, Milena Ćurčić, Nataša Đorđević, Dragana Šeklić, Marina Topuzović and Snežana Marković. 2013. In Vitro Cytotoxic Activity of Origanum vulgare L. on HCT-116 and MDA-MB-231 Cell Lines Plants 2:371-378; doi:10.3390/plants2030371
  • Gordaliza M. 2009. Natural products as leads to anticancer drugs. Clin Transl Oncol 9:767-776.
  • Half E, Arber N. 2009. Colon cancer: Preventive agents and the present status of chemoprevention. Exp. Opin. Pharmacother. 10: 211–219.
  • Hamedi A, Afifi M, Etemadfard H (2017) Investigating chemical composition and indications of hydrosol soft drinks (aromatic waters) used in Persian folk medicine for women's hormonal and reproductive health conditions. J Evid Based Complementary Altern Med 22(4): 824–829.
  • Jemal A, Bray F, Center MM, Ward E, Forman D. Global cancer statistics. Cancer J Clin 2011; 61(2): 69-90.
  • Kendir, G., & Güvenç, A. (2010). Etnobotanik ve Türkiye’de yapılmış etnobotanik çalışmalara genel bir bakış. Hacettepe Üniversitesi Eczacılık Fakültesi Dergisi, (1), 49-80.
  • Kucera LS, Cohen RA, Herrmann EC. 1965. Antiviral Activities of Extracts of the Lemon Balm Plant. Ann NY Acad Sci 130: 474-482
  • Li Y, Zhang ML, Cong B, Wang SM, Dong M, Sauriol F, et al. 2011. Achillinin A, a cytotoxic guaianolide from the flower of Yarrow, Achillea millefolium. Biosci Biotechnol Biochem 75: 1554 6.
  • Linskens, H. F., & Jackson, J. F. (Eds.). (1997). Plant volatile analysis. Berlin: Springer.
  • Merika E, Saif MW, Katz A, Syrigos C, Morse M. Colon cancer vaccines: an update. In vivo 2010; 24(5): 607-28.
  • Mukherjee A, Basu S, Sarkar N, Ghosh A. 2001. Advances in cancer therapy with plant based natural products. Curr. Med. Chem. 12: 1467–1468.
  • Nickavar B, Kamalinejad M, Haj Yahya M, Shafaghi B. 2006. Comparison of the free radical scavenging activity of six Iranian Achillea species. Pharm Biol 44: 208 12.
  • Saeidnia S, Moradi Afrapoli F, Gohari AR, Malmir M. 2009. Cytotoxic flavonoid from Achillea talagonica Bioss. J Med Plants Res 8: 52 6.
  • Sathiyamoorthy P, Lugasi Evgi H, Schlesinger P, Kedar I, Gopas J, Pollack Y, et al. 1999. Screening for cytotoxic and anti malarial activities in desert plants of the Negev and Bedouin market plant products. Pharm Biol 37: 188 95.
  • Shinwari ZK. 2010. Medicinal plants research in Pakistan. J Med Plants Res 4: 161–176.
  • Sivas, H., & Tomsuk, Ö. (2011). Antiproliferative and apoptotic effects of the essential oil of Origanum onites and carvacrol on Hep-G2 cells. Anadolu Unıversıty Journal Of Scıence And Technology, 1: (2) 171-180.
  • Souri E, Amin G, Dehmobed Sharifabadi A, Nazifi A, Farsam H. 2004. Anti oxidative activity of sixty plants from Iran. Iran J Pharm Res 3: 55 9.
  • Srithi K, Balslevb H, Wang P, Srisangac P, Trisonthia C. 2009. Medicinal plant knowledge and its erosion among the Mien (Yao) in Northern Thailand. J Ethnopharm 123:335–342.
  • Tarawneh KA, Irshaid F, Jaran AS, Ezealarab M, Khleifat KM. 2010. Evaluation of anti bacterial and anti oxidant activities of methanolic extracts of some medicinal plants in northern part of Jordan. J Biol Sci 10: 325 32.
  • Tornuk F, Cankurt H, Ozturk I, Sagdic O, Bayram O, Yetim H (2011) Efficacy of various plant hydrosols as natural food sanitizers in reducing Escherichia coli O157:H7 and Salmonella typhimurium on fresh cut carrots and apples. Int J Food Microbiol 148: 30–35.
  • Trifunovic S, Vajs V, Juranic Z, Zizak Z, Tesevic V, Macura S, et al. 2006. Cytotoxic constituents of Achillea clavennae from Montenegro. Phytochemistry 67: 887 93.
  • Weidner, C., Rousseau, M., Plauth, A., Wowro, S. J., Fischer, C., Abdel-Aziz, H., & Sauer, S. (2015). Melissa officinalis extract induces apoptosis and inhibits proliferation in colon cancer cells through formation of reactive oxygen species. Phytomedicine, 22(2), 262-270.
  • Winawer SJ, Sherlock P. 2007. Best practice and research clinical gastroenterology. Colorectal cancer screening 21 (6): 1031.
  • Wojdyło A, Oszmianski J, Czemerys R. 2007. Antioxidant activity and phenolic compounds in 32 selected herbs. Food Chem 105:940 9.
  • World Health Organization. World Health Organization. [Online].; 2010. Available from: http://www.who.int/cancer/detection/colorectalcancer/en/
  • Xavier, C. P., Lima, C. F., Fernandes-Ferreira, M., & Pereira-Wilson, C. (2009). Salvia fruticosa, Salvia officinalis, and rosmarinic acid induce apoptosis and inhibit proliferation of human colorectal cell lines: the role in MAPK/ERK pathway. Nutrition and cancer, 61(4), 564-571.

Comparative Cytotoxic Effects of the Hydrosols of Some Ethnobotanic Plants

Yıl 2020, Cilt 3, Sayı 2, 97 - 103, 24.12.2020
https://doi.org/10.38093/cupmap.765089

Öz

Hydrosols are aqueous solutions and by-products of the essential oil distillation procedure. They have many medicinal benefits because contain the water-soluble components, vitamins and minerals of the plant that has been distilled. In this study, the cytotoxic effects of hydrosols obtained from five ethnobotanical plants (Melissa officinalis L., Achillea teretifolia Willd, Achillea aleppica subsp. zederbauri (Hayek) Hub.-Mor., Origanum onites and Salvia fruticosa Mill.) were investigated. MTT assay was used to determine the cytotoxic effect of hydrosols. Based on the results of cytotoxicity assay, the most effective extract was obtained from Origanum onites and the next effective extract from Melissa officinalis. On the other hand, both Achillea extracts showed low cytotoxic activity. Consequently, this study provides some criticism on the potentials of some plants traditionally used as an anticancer agent, and also shows that there is more need to investigate the cause of cell death and active substances.

Kaynakça

  • Adnan M, Ullah I, Tariq A, Murad W, Azizullah A, Khan A, Ali N. 2014. Ethnomedicine use in the war affected region of Northwest Pakistan. J Ethnobiol Ethnomed 10: 16.
  • Ali N, Shah SW, Shah I, Ahmed G, Ghias M, Khan I. Cytotoxic and anthelmintic potential of crude saponins isolated from Achillea wilhelmsii C. Koch and Teucrium stocksianum Boiss. BMC Complement Altern Med 2011;11:106.
  • Bisset NG.1994. Herbal Drugs and Phytopharmaceuticals: A handbook for practice scientific basis (1st ed.). Stuttgart, Germany: Medpharm GmbH Scientifiv Publisher.
  • Bozin B, Mimica Dukic N, Bogavac M, Suvajdzic L, Simin N, Samojlik I, et al. 2008. Chemical composition, antioxidant and antibacterial properties of Achillea collina Becker ex Heimerl s.l. and A. pannonica Scheele essential oils. Molecules 13: 2058 68.
  • de Sousa AC, Alviano DS, Blank AF, Alves PB, Alviano CS, Gattass CR. 2004. Melissa officinalis L. essential oil: antitumoral and antioxidant activities. J Pharm Parmacol 56: 677-681.
  • Demir S, Ayazoglu Demir E, Aliyazicioglu Y, 2020. Selective Cytotoxic Effect of Astaxanthin on Human Lung and Colon Cancer Cells. KSU J. Agric Nat 23 (6): 1489-1494.
  • Elif Burcu Bali, Leyla Açık, Pınar Elçi, Meral Sarper, Ferit Avcu and Mecit Vural. 2015. In vitro anti-oxidant, cytotoxic and pro-apoptotic effects of Achillea teretifolia Willd extracts on human prostate cancer cell lines. Pharmacogn Mag. Oct; 11(Suppl 2): S308–S315.
  • Encalada, M. A., Hoyos, K. M., Rehecho, S., Berasategi, I., de Ciriano, M. G. Í., Ansorena, D., ... & Calvo, M. I. (2011). Anti-proliferative effect of Melissa officinalis on human colon cancer cell line. Plant Foods for Human Nutrition, 66(4), 328-334.
  • Ferlay J, Shim HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 2010; 127(1): 2893-917.
  • Filip Grbović, Milan S. Stanković, Milena Ćurčić, Nataša Đorđević, Dragana Šeklić, Marina Topuzović and Snežana Marković. 2013. In Vitro Cytotoxic Activity of Origanum vulgare L. on HCT-116 and MDA-MB-231 Cell Lines Plants 2:371-378; doi:10.3390/plants2030371
  • Gordaliza M. 2009. Natural products as leads to anticancer drugs. Clin Transl Oncol 9:767-776.
  • Half E, Arber N. 2009. Colon cancer: Preventive agents and the present status of chemoprevention. Exp. Opin. Pharmacother. 10: 211–219.
  • Hamedi A, Afifi M, Etemadfard H (2017) Investigating chemical composition and indications of hydrosol soft drinks (aromatic waters) used in Persian folk medicine for women's hormonal and reproductive health conditions. J Evid Based Complementary Altern Med 22(4): 824–829.
  • Jemal A, Bray F, Center MM, Ward E, Forman D. Global cancer statistics. Cancer J Clin 2011; 61(2): 69-90.
  • Kendir, G., & Güvenç, A. (2010). Etnobotanik ve Türkiye’de yapılmış etnobotanik çalışmalara genel bir bakış. Hacettepe Üniversitesi Eczacılık Fakültesi Dergisi, (1), 49-80.
  • Kucera LS, Cohen RA, Herrmann EC. 1965. Antiviral Activities of Extracts of the Lemon Balm Plant. Ann NY Acad Sci 130: 474-482
  • Li Y, Zhang ML, Cong B, Wang SM, Dong M, Sauriol F, et al. 2011. Achillinin A, a cytotoxic guaianolide from the flower of Yarrow, Achillea millefolium. Biosci Biotechnol Biochem 75: 1554 6.
  • Linskens, H. F., & Jackson, J. F. (Eds.). (1997). Plant volatile analysis. Berlin: Springer.
  • Merika E, Saif MW, Katz A, Syrigos C, Morse M. Colon cancer vaccines: an update. In vivo 2010; 24(5): 607-28.
  • Mukherjee A, Basu S, Sarkar N, Ghosh A. 2001. Advances in cancer therapy with plant based natural products. Curr. Med. Chem. 12: 1467–1468.
  • Nickavar B, Kamalinejad M, Haj Yahya M, Shafaghi B. 2006. Comparison of the free radical scavenging activity of six Iranian Achillea species. Pharm Biol 44: 208 12.
  • Saeidnia S, Moradi Afrapoli F, Gohari AR, Malmir M. 2009. Cytotoxic flavonoid from Achillea talagonica Bioss. J Med Plants Res 8: 52 6.
  • Sathiyamoorthy P, Lugasi Evgi H, Schlesinger P, Kedar I, Gopas J, Pollack Y, et al. 1999. Screening for cytotoxic and anti malarial activities in desert plants of the Negev and Bedouin market plant products. Pharm Biol 37: 188 95.
  • Shinwari ZK. 2010. Medicinal plants research in Pakistan. J Med Plants Res 4: 161–176.
  • Sivas, H., & Tomsuk, Ö. (2011). Antiproliferative and apoptotic effects of the essential oil of Origanum onites and carvacrol on Hep-G2 cells. Anadolu Unıversıty Journal Of Scıence And Technology, 1: (2) 171-180.
  • Souri E, Amin G, Dehmobed Sharifabadi A, Nazifi A, Farsam H. 2004. Anti oxidative activity of sixty plants from Iran. Iran J Pharm Res 3: 55 9.
  • Srithi K, Balslevb H, Wang P, Srisangac P, Trisonthia C. 2009. Medicinal plant knowledge and its erosion among the Mien (Yao) in Northern Thailand. J Ethnopharm 123:335–342.
  • Tarawneh KA, Irshaid F, Jaran AS, Ezealarab M, Khleifat KM. 2010. Evaluation of anti bacterial and anti oxidant activities of methanolic extracts of some medicinal plants in northern part of Jordan. J Biol Sci 10: 325 32.
  • Tornuk F, Cankurt H, Ozturk I, Sagdic O, Bayram O, Yetim H (2011) Efficacy of various plant hydrosols as natural food sanitizers in reducing Escherichia coli O157:H7 and Salmonella typhimurium on fresh cut carrots and apples. Int J Food Microbiol 148: 30–35.
  • Trifunovic S, Vajs V, Juranic Z, Zizak Z, Tesevic V, Macura S, et al. 2006. Cytotoxic constituents of Achillea clavennae from Montenegro. Phytochemistry 67: 887 93.
  • Weidner, C., Rousseau, M., Plauth, A., Wowro, S. J., Fischer, C., Abdel-Aziz, H., & Sauer, S. (2015). Melissa officinalis extract induces apoptosis and inhibits proliferation in colon cancer cells through formation of reactive oxygen species. Phytomedicine, 22(2), 262-270.
  • Winawer SJ, Sherlock P. 2007. Best practice and research clinical gastroenterology. Colorectal cancer screening 21 (6): 1031.
  • Wojdyło A, Oszmianski J, Czemerys R. 2007. Antioxidant activity and phenolic compounds in 32 selected herbs. Food Chem 105:940 9.
  • World Health Organization. World Health Organization. [Online].; 2010. Available from: http://www.who.int/cancer/detection/colorectalcancer/en/
  • Xavier, C. P., Lima, C. F., Fernandes-Ferreira, M., & Pereira-Wilson, C. (2009). Salvia fruticosa, Salvia officinalis, and rosmarinic acid induce apoptosis and inhibit proliferation of human colorectal cell lines: the role in MAPK/ERK pathway. Nutrition and cancer, 61(4), 564-571.

Ayrıntılar

Birincil Dil İngilizce
Konular Biyoloji
Bölüm Research Articles
Yazarlar

Ela Nur ŞİMŞEK SEZER (Sorumlu Yazar)
FACULTY OF SCIENCE
0000-0003-2805-7204
Türkiye


Meryem BOZKURT
FACULTY OF SCIENCE
0000-0003-0338-0849
Türkiye


Eray TULUKCU
ÇUMRA VOCATIONAL SCHOOL
0000-0002-1893-144X
Türkiye


Tuna UYSAL
FACULTY OF SCIENCE
0000-0001-9968-5633
Türkiye

Yayımlanma Tarihi 24 Aralık 2020
Yayınlandığı Sayı Yıl 2020, Cilt 3, Sayı 2

Kaynak Göster

APA Şimşek Sezer, E. N. , Bozkurt, M. , Tulukcu, E. & Uysal, T. (2020). Comparative Cytotoxic Effects of the Hydrosols of Some Ethnobotanic Plants . Current Perspectives on Medicinal and Aromatic Plants (CUPMAP) , 3 (2) , 97-103 . DOI: 10.38093/cupmap.765089

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