Romatoid Artrit Akciğer Tutulumu Olan Hastalarda Hematolojik Parametrelerin Tanıya Katkısı

Abstract

Romatoid artrit (RA) yaygın otoimmün bir hastalık olup akciğer tutulumu en sık görülen eklem dışı bulgudur. Çalışmamız RA'li hastalarda hematolojik parametrelerin akciğer tutulumu tanısına katkısını araştırmayı amaçlamaktadır. RA tanısı alan bireyler Toraks Bilgisayarlı Tomografideki akciğer tutulumuna göre iki gruba ayrıldı. Tüm hastalarda C-reaktif protein (CRP), eritrosit sedimantasyon hızı (ESH), nötrofil, lenfosit, monosit, trombosit, nötrofil/lenfosit oranı (NLO), monosit/lenfosit oranı (MLO), sistemik inflamatuar indeks (Sİİ) değerlendirildi. 75 RA hastasının 29'unda akciğer tutulumu saptanırken, 46 hastada akciğer tutulumu görülmedi. Akciğer tutulumu olan hastalarda CRP, ESR ve nötrofiller yüksekti ve istatistiksel olarak belirgin anlamlı fark izlendi. Akciğer tutulumu olan hastalarda lenfosit sayısı düşüktü ve istatistiksel olarak anlamlıydı. Akciğer tutulumu olan hastalarda NLR, NMO ve SII oranları yüksekti ve istatistiksel olarak anlamlıydı. Bu çalışmada hematolojik parametrelerin RA akciğer tutulumunun tanısına katkı sağladığı görülmektedir.

Keywords

• Romatoid Artrit
• Hematolojik Testler
• Akciğer İnflamasyonu

Diagnostic Contribution of Hematological Parameters in Patients with Lung İnvolvement in Rheumatoid Arthritis

Abstract

Rheumatoid arthritis (RA) is a prevalent autoimmune condition, with lung involvement being its most frequent extra-articular manifestation. Our study aims to investigate the contribution of hematological parameters to diagnosing lung involvement in patients with RA. Individuals with RA were divided into two groups according to lung involvement in thorax computed tomography. C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), neutrophil, lymphocyte, monocyte, platelet, neutrophil/lymphocyte ratio (NLR), monocyte/lymphocyte ratio (MLR) and systemic immune-inflammatory index (SII) were evaluated in all patients. Twenty-nine of the seventy-five RA patients were found to have lung involvement, and lung involvement was not observed in forty-six patients. CRP, ESR, and neutrophils were high in patients with lung involvement and a statistically notable distinction was observed. Lymphocyte count was low in patients with lung involvement and was statistically significant. NLR, NMO, and SII rates were high in patients with lung involvement and were statistically significant. It is observed that hematological parameters contribute to diagnosing RA lung involvement.

Keywords

• Rheumatoid arthritis
• lung inflammation
• hematological tests

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