Retrospective evaluation of cases with tuberculosis meningitis: Single Center Experience

Yasemin Demir Yiğit; Ebral Yiğit

EN

Retrospective evaluation of cases with tuberculosis meningitis: Single Center Experience

An Erratum to this article was published on October 29, 2023. https://dergipark.org.tr/en/pub/dahudermj/article/1382722

Abstract

A total of 172 patients were retrospectively investigated who were admitted to the Pediatric Department of Dicle University School of Medicine between 1997 and 2005 with the diagnosis of tuberculous meningitis. Demographic data, clinical, laboratory, and radiological findings and responses to treatment were analyzed. Of all patients, 124 (%72,1) were under 5 years of age and 109 were males. The most common symptoms on admission were fever (%71), vomiting (%60), convulsion (%38), and headache (%31). Fouty seven (%23,8 ) patients had a positive family history of tuberculosis. Tuberculin skin test positivity was seen in %19,6 and %20,1 had positive BCG scar. Of all patients 32 (%18,6) were in stage I, 82 (%47,7) were in stage II and 58 (%33,7) were in stage III on admission. Chest X-Ray showed pathological findings in %60,9 of all patients. Hydrocephalus was detected in 149 patients on cranial tomography. A ventriculoperitoneal shunt was performed in 79 patients with hydrocephalus. Totally, 24 deaths were detected from all patient records. Since the diagnosis of tuberculous meningitis is difficult and the disease has a high morbidity and mortality rate, the importance of preventive measures in the control of the disease has been emphasized in this study

Keywords

Chidren, tuberculosis, meningitis

References

1. World Health Organisation, TB: A global emergency. WHO Report on the TB epidemic Geneva, 1994; 177: 1-15
2.Türkiye'de verem hastalığıının seyri üzerine bir araştırma. Sağlık bakanlığı Verem Savas Daire Baskanlığı Yayanı, Ankara 1984
3. Topçu, A. W., Söyletir, G., & Doğanay, M. (Eds.). (1996). İnfeksiyon Hastalıkları. Nobel Tıp Kitabevleri.
4. Bhargava S, Gupta AK, Tandon PN. Tuberculous meningitis--a CT study. Br J Radiol. 1982 Mar;55(651):189-96. doi: 10.1259/0007-1285-55-651-189. PMID: 7066619.
5. Garg RK. Tuberculosis of the central nervous system. Postgrad Med J. 1999 Mar;75(881):133-40. doi: 10.1136/pgmj.75.881.133. PMID: 10448488; PMCID: PMC1741157.
6.Katz SL, Gershon AA, Hotez PJ. Krugman's Infectious Diseases of Children. 10th ed. St Louis: Mosby-Year book, Inc 1998: 571-604
7. Zuger A, Lowy FD. Tuberculosis of the central nervous system. In: Scheld WM, Whitley RS, Durock DJ (eds). Infections of the Central Nervous System. 2nd ed. Philadelphia: Lippincott-Raven, 1997:417-43
8.Ahuja GK, Monhan KK, Prasad K, Behari M. Diagnostic criteria for tuberculous meningitis and their validation. Tubercle Lung Dis 1994; 75: 149-152.
9.Colditz G, Berkey CS, Masteller F, et al. The efficacy of Bacillus Calmette Guerin vaccination of newborns and infants in the published literature. Pediatrics 1995; 96: 29-35
10.Behrman RE, Kliegman RM, Jenson 1-1B. Nelson Textbook of Pediatrics. 16th ed. Philadelphia, W. B. Saunders Comp, 2000

11. Starke JR. Tuberculosis in childhood. Current opininom in pediatr 1995;268-277
12.Burroughs M, Beitel A, Kawamura A, Revai K, Ricafort R, Chiu K, Jacobs R, Riley L. Clinical presentation of tuberculosis in culture-positive children. Pediatric Tuberculosis Consortium. Pediatr Infect Dis J. 1999 May;18(5):440-6. doi: 10.1097/00006454-199905000-00008. PMID: 10353517.
13.ÖzçeIik U, Göçmen A Tüberküloz Menenjit. Katkı Pediatri Dergisi 1992;13(1):30-40
14. Yaramiş A, Gurkan F, Elevli M, Söker M, Haspolat K, Kirbaş G, Taş MA. Central nervous system tuberculosis in children: a review of 214 cases. Pediatrics. 1998 Nov;102(5):E49. doi: 10.1542/peds.102.5.e49. PMID: 9794979.
15. Nguyen LN, Kox LF, Pham LD, Kuijper S, Kolk AH. The potential contribution of the polymerase chain reaction to the diagnosis of tuberculous meningitis. Arch Neurol. 1996 Aug;53(8):771-6. doi: 10.1001/archneur.1996.00550080093017. PMID: 8759984.
16. SMITH HV, VOLLUM RL. The diagnosis of tuberculous meningitis. Br Med Bull. 1954;10(2):140-5. doi: 10.1093/oxfordjournals.bmb.a069392. PMID: 13160425.
17. Donald PR, Schoeman JF, Van Zyl LE, De Villiers JN, Pretorius M, Springer P. Intensive short course chemotherapy in the management of tuberculous meningitis. Int J Tuberc Lung Dis. 1998 Sep;2(9):704-11. PMID: 9755923.
18. Girgis, N. I., Sultan, Y., Farid, Z., Mansour, M. M., Erian, M. W., Hanna, L. S., & Mateczun, A. J. (1998). Tuberculosis meningitis, Abbassia Fever Hospital-Naval Medical Research Unit No. 3-Cairo, Egypt, from 1976 to 1996. The American journal of tropical medicine and hygiene, 58(1), 28-34.
19. Molavi A, LeFrock JL. Tuberculous meningitis. Med Clin North Am. 1985 Mar;69(2):315-31. doi: 10.1016/s0025-7125(16)31045-8. PMID: 3990437.
20- Newton RW. Tuberculous meningitis. Arch Dis Child. 1994 May;70(5):364-6. doi: 10.1136/adc.70.5.364. PMID: 8017954; PMCID: PMC1029815.
21. Ahuja GK, Mohan KK, Prasad K, Behari M. Diagnostic criteria for tuberculous meningitis and their validation. Tuber Lung Dis. 1994 Apr;75(2):149-52. doi: 10.1016/0962-8479(94)90045-0. PMID: 8032049.
22.Doerr CA, Starke JR, Ong LT. Clinical and public health aspects of tuberculous meningitis in children. J Pediatr. 1995 Jul;127(1):27-33. doi: 10.1016/s0022-3476(95)70252-0. PMID: 7608807.
23. Tang PS, Low LC. Radiological and clinical features of basal ganglia infarction in tuberculous meningitis. Aust Paediatr J. 1989 Dec;25(6):361-2. doi: 10.1111/j.1440-1754.1989.tb02357.x. PMID: 2619640.
24. Jinkins JR. Computed tomography of intracranial tuberculosis. Neuroradiology. 1991;33(2):126-35. doi: 10.1007/BF00588250. PMID: 2046896.
25. Işık Y. Tüberküloz. In Pediatri. Neyzi O, Ertu§rul T ed 3. Baski Nobel TIP Kitabevleri. Istanbul 2002; s: 523-534

Details

Primary Language

English

Subjects

Internal Diseases

Journal Section

Research Article

Authors

Yasemin Demir Yiğit
0000-0002-6426-8490
Türkiye

Ebral Yiğit ^*
0000-0001-8766-0754
Türkiye

Publication Date

January 29, 2022

Submission Date

December 23, 2021

Acceptance Date

January 11, 2022

Published in Issue

Year 2022 Volume: 2 Number: 1

IZ

https://izlik.org/JA42XB59SM

APA

Demir Yiğit, Y., & Yiğit, E. (2022). Retrospective evaluation of cases with tuberculosis meningitis: Single Center Experience. DAHUDER Medical Journal, 2(1), 16-23. https://izlik.org/JA42XB59SM

AMA

1.Demir Yiğit Y, Yiğit E. Retrospective evaluation of cases with tuberculosis meningitis: Single Center Experience. DAHUDER MJ. 2022;2(1):16-23. https://izlik.org/JA42XB59SM

Chicago

Demir Yiğit, Yasemin, and Ebral Yiğit. 2022. “Retrospective Evaluation of Cases With Tuberculosis Meningitis: Single Center Experience”. DAHUDER Medical Journal 2 (1): 16-23. https://izlik.org/JA42XB59SM.

EndNote

Demir Yiğit Y, Yiğit E (January 1, 2022) Retrospective evaluation of cases with tuberculosis meningitis: Single Center Experience. DAHUDER Medical Journal 2 1 16–23.

IEEE

[1]Y. Demir Yiğit and E. Yiğit, “Retrospective evaluation of cases with tuberculosis meningitis: Single Center Experience”, DAHUDER MJ, vol. 2, no. 1, pp. 16–23, Jan. 2022, [Online]. Available: https://izlik.org/JA42XB59SM

ISNAD

Demir Yiğit, Yasemin - Yiğit, Ebral. “Retrospective Evaluation of Cases With Tuberculosis Meningitis: Single Center Experience”. DAHUDER Medical Journal 2/1 (January 1, 2022): 16-23. https://izlik.org/JA42XB59SM.

JAMA

1.Demir Yiğit Y, Yiğit E. Retrospective evaluation of cases with tuberculosis meningitis: Single Center Experience. DAHUDER MJ. 2022;2:16–23.

MLA

Demir Yiğit, Yasemin, and Ebral Yiğit. “Retrospective Evaluation of Cases With Tuberculosis Meningitis: Single Center Experience”. DAHUDER Medical Journal, vol. 2, no. 1, Jan. 2022, pp. 16-23, https://izlik.org/JA42XB59SM.

Vancouver

1.Yasemin Demir Yiğit, Ebral Yiğit. Retrospective evaluation of cases with tuberculosis meningitis: Single Center Experience. DAHUDER MJ [Internet]. 2022 Jan. 1;2(1):16-23. Available from: https://izlik.org/JA42XB59SM